Zobrazeno 1 - 10
of 17
pro vyhledávání: '"K M, Metters"'
Autor:
T. R. Jones, M. Labelle, M. Belley, E. Champion, L. Charette, J. Evans, A. W. Ford-Hutchinson, J. -Y. Gauthier, A. Lord, P. Masson, M. McAuliffe, C. S. McFarlane, K. M. Metters, C. Pickett, H. Piechuta, C. Rochette, I. W. Rodger, N. Sawyer, R. N. Yoyng, R. Zamboni, W. M. Abraham
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 73:191-201
Montelukast sodium (Singulair™), also known as MK-0476 (1-(((1(R)-(3-(2-(7-chloro-2-quinolinyl)-(E)-ethenyl)phenyl)(3-2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane) acetic acid sodium salt, is a potent and selective inhibitor of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6921a19999723f662391309297b826b0
https://doi.org/10.1139/y95-028
https://doi.org/10.1139/y95-028
Autor:
M. LABELLE, M. BELLEY, Y. GAREAU, J. Y. GAUTHIER, D. GUAY, R. GORDON, S. G. GROSSMAN, T. R. JONES, Y. LEBLANC, M. MCAULIFFE, C. MCFARLANE, P. MASSON, K. M. METTERS, N. OUIMET, D. H. PATRICK, H. PIECHUTA, C. ROCHETTE, N. SAWYER, Y. B. XIANG, C. B. PICKETT, A. W. FORD-HUTCHINSON, ET AL. ET AL.
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17e5febd2b8d411d166f9eb768e860c6
https://doi.org/10.1002/chin.199527182
https://doi.org/10.1002/chin.199527182
Autor:
T. R. Jones, R. Zamboni, M. Belley, E. Champion, L. Charette, A. W. Ford-Hutchinson, J.-Y. Gauthier, S. Leger, A. Lord, P. Masson, C. S. McFarlane, K. M. Metters, C. Pickett, H. Piechuta, R. N. Young
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 69:1847-1854
Verlukast (MK-679) (3-(((3-(2-(7-chloro-2-quinolinyl)-(E)-ethenyl)phenyl)((3-(dimethylamino)-3-oxopropyl)thio)methyl)-thio)propionic acid) is a potent and selective inhibitor of [3H]leukotriene D4 binding in guinea-pig (IC50 = 3.1 ± 0.5 nM) and huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16057f5bd2378ba4452bb1d2cafad6c2
https://doi.org/10.1139/y91-273
https://doi.org/10.1139/y91-273
Autor:
William K. Stell, Catherine Rougeot, Jean Rossier, K. M. Metters, Fernand Dray, Michel Chaminade
Publikováno v:
Journal of Neurochemistry. 54:434-443
Synenkephalin (SYN), the nonopioid amino-terminal portion of proenkephalin (PRO), is stable and well conserved in mammals and therefore a promising marker for PRO systems. We immunized rabbits with synthetic [Tyr63]SYN(63-70)-octapeptide, coupled by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d7a40cc0f0f0a4a55fdd5564cd9c95b
https://doi.org/10.1111/j.1471-4159.1990.tb01891.x
https://doi.org/10.1111/j.1471-4159.1990.tb01891.x
Autor:
D, Slipetz, S, Buchanan, C, Mackereth, N, Brewer, V, Pellow, C, Hao, M, Adam, M, Abramovitz, K M, Metters
Publikováno v:
Biochemical pharmacology. 62(8)
The prostaglandin E2 (PGE2) EP4 subtype is one of four prostanoid receptors that use PGE2 as the preferred ligand. We have investigated the agonist-mediated regulation of EP4 using a multifaceted approach. Short-term (30 min) agonist challenge of rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75fdaf425322c23ec9fb4576a7f62577
https://pubmed.ncbi.nlm.nih.gov/11597569
https://pubmed.ncbi.nlm.nih.gov/11597569
Publikováno v:
British journal of pharmacology. 128(4)
1 We characterized the regulation of cyclooxygenase-2 (COX-2) at the mRNA, protein and mediator level in two rat models of acute inflammation, carrageenan-induced paw oedema and mechanical hyperalgesia. 2 Carrageenan was injected in the hind paw of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa85dabcdaa2283bbbc06b06a099d108
https://pubmed.ncbi.nlm.nih.gov/10556918
https://pubmed.ncbi.nlm.nih.gov/10556918
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 269(3)
Agonist-induced changes in intracellular calcium ion concentration ([Ca++]i) were examined in human monocytic leukemia THP-1 cells loaded with fura 2/acetoxymethyl ester (fura 2/AM). Leukotriene (LT)D4 induced a concentration-dependent biphasic respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27d300d8b2ee03d41b697017bc70fe29
https://pubmed.ncbi.nlm.nih.gov/8014876
https://pubmed.ncbi.nlm.nih.gov/8014876
Autor:
K M, Metters, R J, Zamboni
Publikováno v:
The Journal of biological chemistry. 268(9)
The leukotriene (LT)D4 receptor has been defined as a G-protein-coupled receptor. In order to characterize this receptor, an iodinated, photoactivatable azido derivative of LTD4 (125I-azido-LTD4) has been synthesized for use as a photoaffinity probe.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b5a34f3afaabc0353195190e73b7cf9d
https://pubmed.ncbi.nlm.nih.gov/8384212
https://pubmed.ncbi.nlm.nih.gov/8384212
Autor:
T. R. Jones, M. Labelle, M. Belley, E. Champion, L. Charette, J. Evans, A. W. Ford-Hutchinson, J.-Y. Gauthier, A. Lord, P. Masson, M. McAuliffe, C. S. McFarlane, K. M. Metters, C. Pickett, H. Piechuta, C. Rochette, I. W. Rodger, N. Sawyer, R. N. Young, R. Zamboni, W. M. Abraham
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 73:747-747
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16203e824260a2f25be17a95a82ffdbd
https://doi.org/10.1139/y95-098
https://doi.org/10.1139/y95-098
Autor:
Jean Rossier, Odaly Toffoletto, Eduarado Brandt de Oliveira, Antonio C.M. Camargo, K. M. Metters
Publikováno v:
Journal of Neurochemistry. 48:1258-1263
Endo-oligopeptidase A, highly purified from the cytosol fraction of bovine brain by immunoaffinity chroma-tography, has been characterized as a thiol endopeptidase. This enzyme, known to hydrolyze the Phe5-Ser6 bond of bradykinin and the Arg8-Arg9 bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7321cf8f5a52f33a8a8c9ca24f23f670
https://doi.org/10.1111/j.1471-4159.1987.tb05655.x
https://doi.org/10.1111/j.1471-4159.1987.tb05655.x