Zobrazeno 1 - 5
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pro vyhledávání: '"K M, Kleinow"'
Publikováno v:
Xenobiotica. 23:961-972
1. The pharmacokinetics, disposition and bioavailability of nalidixic acid were examined in Rainbow Trout following i.v. and per os administration (5 mg/kg). 2. Nalidixic acid was biexponentially eliminated from plasma following i.v. dosing (t1/2 alp
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 29(5)
The intestinal bioavailability and biotransformation of 3-hydroxybenzo(a)pyrene, a major metabolite of benzo(a)pyrene in many animal species, was investigated in an in situ isolated intestinal preparation from the channel catfish, and in vitro with p
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 25(3)
These studies demonstrated that intestinal mucosa of the channel catfish contained activities comparable with liver for several phase 2 xenobiotic-metabolizing enzymes, and showed that CYP1A-dependent monooxygenase activities were inducible in intest
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 14(1)
The distribution of [2,3-14C]acrylamide was studied in fingerling rainbow trout by whole-body autoradiography. Fish weighing approximately 7 g were injected ip with 3.2 mg/kg [14C]acrylamide (0.1 microCi/g). One group of fish was kept in a fresh flow
Autor:
K M, Kleinow, J J, Lech
Publikováno v:
Veterinary and human toxicology. 30
The pharmacokinetics and metabolism of sulfadimethoxine (SDM) was examined in the rainbow trout. Results from pharmacokinetic studies indicate a lengthening of the SDM half-life when administration was shifted from single to a multiple dose regime. I