Zobrazeno 1 - 10
of 16
pro vyhledávání: '"K M, Hummel"'
Publikováno v:
The Journal of Immunology. 159:861-869
The anaphylatoxin C5a has been implicated in the pathogenesis of bacterial meningitis as a potent mediator of inflammation in the subarachnoid space. We investigated the expression of the receptor for C5a (C5aR) in brains of mice with experimental Li
Autor:
P K, Petrow, D, Wernicke, C, Schulze Westhoff, K M, Hummel, R, Bräuer, J, Kriegsmann, E, Gromnica-Ihle, R E, Gay, S, Gay
Publikováno v:
Annals of the rheumatic diseases. 61(5)
Objective: To study the pattern and cell type-specificity of collagenase 3, membrane-type 1 matrix metalloproteinase (MT1-MMP), and gelatinase A mRNA expression in the synovial membrane in rheumatoid arthritis (RA). Methods: The mRNA expression of co
Publikováno v:
Arthritis and rheumatism. 44(8)
To relate the expression of proteases in the lining and sublining layers of the synovial membrane to the rate of joint damage during 1 year in patients with early inflammatory arthritis.Samples of synovial membrane were obtained by closed-needle biop
Publikováno v:
Arthritis Research
In the present study, we searched for mutant PTEN transcripts in aggressive rheumatoid arthritis synovial fibroblasts (RA-SF) and studied the expression of PTEN in RA. By automated sequencing, no evidence for the presence of mutant PTEN transcripts w
Autor:
P K, Petrow, K M, Hummel, J, Schedel, J K, Franz, C L, Klein, U, Müller-Ladner, J, Kriegsmann, P L, Chang, C W, Prince, R E, Gay, S, Gay
Publikováno v:
Arthritis and rheumatism. 43(7)
Osteopontin (OPN) is an extracellular matrix protein that has been implicated in the interactions between tumor cells and host matrix, including those involved in invasion and spread of tumor cells. Because joint destruction in rheumatoid arthritis (
Publikováno v:
Rheumatology (Oxford, England). 38(1)
Objective. To examine the expression of the matrix metalloproteinase, MMP-1, and the cysteine proteases, cathepsin B (CB) and cathepsin L (CL), in the synovial membrane (SM ) of patients with early inflammatory arthritis. Methods. Samples of SM were
Autor:
T, Pap, G, Pap, K M, Hummel, J K, Franz, E, Jeisy, I, Sainsbury, R E, Gay, M, Billingham, W, Neumann, S, Gay
Publikováno v:
The Journal of rheumatology. 26(1)
To investigate the distribution pattern of membrane-type-1 matrix metalloproteinase (MT1-MMP) within the synovial-like interface membranes of failed prosthetic joints.Interface tissue around loose arthroplasties containing both fibrous membrane and a
Autor:
J K, Franz, S A, Kolb, K M, Hummel, F, Lahrtz, M, Neidhart, W K, Aicher, T, Pap, R E, Gay, A, Fontana, S, Gay
Publikováno v:
European journal of immunology. 28(9)
The massive infiltration of synovium with CD4+ T cells during the course of rheumatoid arthritis (RA) implies the expression of chemoattractant factors by resident synovial cells. Therefore, we analyzed the expression of IL-16, a potent chemoattracta
Autor:
K. M. Hummel, M. Neidhart, V. Vilim, N. Hauser, W. K. Aicher, R. E. Gay, S. Gay, H. J. Hauselmann
Publikováno v:
Scopus-Elsevier
We investigated the expression of cartilage oligomeric matrix protein (COMP) in normal and rheumatoid arthritis (RA) synovial fibroblasts. In situ hybridization (ISH) was conducted on synovial specimens from five RA patients applying specific probes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf0517a6ec16ac680c287af02880b3cf
https://www.zora.uzh.ch/id/eprint/155118/
https://www.zora.uzh.ch/id/eprint/155118/
Publikováno v:
Archivum immunologiae et therapiae experimentalis. 46(1)
The synovium in rheumatoid arthritis (RA) is characterized by an increase in lining layer thickness and infiltration of inflammatory cells into the sublining area. Fibroblasts in the lining layer develop the appearance of "transformed cells", under t