Zobrazeno 1 - 10
of 18
pro vyhledávání: '"K M, Esser"'
Autor:
M D Sofronski, K. M. Esser, John F. Renz, Jerome Vernick, Reuven Rabinovici, Leonard Hillegas, Giora Z. Feuerstein
Publikováno v:
Journal of Clinical Investigation. 89:1669-1673
Interleukin-2 was recently shown to cause acute lung injury characterized by microvascular permeability defect, interstitial edema, and leukosequestration. Similar responses can also be produced by platelet activating factor (PAF). Thus, the present
Autor:
K. M. Esser, Thanh D. Nguyen, Jeffry J. Leary, Robin Saltzman, Ron Boon, Matthew R. Quail, Karen Duffy, Teresa H. Bacon, Leslie A. Locke, Robert T. Sarisky
Publikováno v:
Archives of virology. 148(9)
Asusceptibility testing program was established to determine the prevalence of resistance to penciclovir among herpes simplex virus isolates collected from patients participating in 11 world-wide clinical trials involving penciclovir (topical or intr
Publikováno v:
Circulatory shock. 44(4)
Three inhibitors of calcium-dependent cyclic adenosine 3'5'-monophosphate (cAMP) dependent phosphodiesterase IV (PDE IV) were evaluated for their effects on lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF) production in vitro and in vivo
Autor:
R, Rabinovici, P J, Bugelski, K M, Esser, L M, Hillegass, D E, Griswold, J, Vernick, G, Feuerstein
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 267(3)
We have reported recently that lipopolysaccharide endotoxin and platelet activating factor cooperate in priming relationships to elicit lung microvascular injury. Lung injury was associated with elevated serum levels of tumor necrosis factor-alpha (T
Publikováno v:
Pharmacology. 46(5)
The present study was designed to investigate the effects of fluid administration on survival in endotoxemic or septicemic male Sprague-Dawley rats. Endotoxemia was induced by intravenous injection of Escherichia coli lipopolysaccharide (LPS), and se
Autor:
Jerome Vernick, Reuven Rabinovici, Giora Z. Feuerstein, L. M. Hillegass, P. J. Bugelski, K. M. Esser
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 74(4)
We recently reported that the combined administration of lipopolysaccharide (LPS) and platelet-activating factor (PAF) in rats, at doses that are completely devoid of any effect when given alone, caused lung injury characterized by neutrophil adhesio
Publikováno v:
Circulatory shock. 39(3)
The following study was performed to determine the effects of phosphodiesterase IV (PDE-IV) inhibition and its attenuation of tumor necrosis factor (TNF alpha) production in a rat model of the Adult Respiratory Distress Syndrome (ARDS). Rats were eit
Publikováno v:
Drugs under experimental and clinical research. 19(6)
The stimulation of tumour necrosis factor alpha (TNF alpha) production by lipopolysaccharide (LPS) has been widely used, both in vitro and in vivo, to examine the biochemistry and pharmacology of inflammatory cytokine production. It appears that clas
Publikováno v:
Circulatory shock. 37(4)
SKF 105809 is a structurally novel dual inhibitor of lipoxygenase and cyclooxygenase-mediated arachidonic acid (AA) metabolism, which has demonstrated antiinflammatory activity in rodent models of inflammation. In addition, the active metabolite of t
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 255(1)
BN 50739, a new PAF receptor antagonist, was tested in vitro and in vivo for its capacity to block PAF, endotoxin and recombinant human tumor necrosis factor-alpha (rTNF)-mediated effects. In vitro, BN 50739 blocked PAF-induced platelet aggregation b