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Strain differences in adrenal CYP2D16 expression in guinea pigs. Relationship to xenobiotic metabolism

Autor: Y, Huang, Q, Jiang, J M, Voigt, K M, Debolt, H D, Colby

Publikováno v: Biochemical pharmacology. 52(12)

Experiments were done to determine the mechanisms responsible for differences in adrenal microsomal xenobiotic metabolism between Strain 13 and English Short-Hair (ESH) guinea pigs. The rates of adrenal xenobiotic metabolism (bufuralol 1'-hydroxylase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dec6d2b57d7d184c30c3a175171b1e51
https://pubmed.ncbi.nlm.nih.gov/8951353

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Inactivation of adrenal cytochromes P450 by 1-aminobenzotriazole. Divergence of in vivo and in vitro actions

Autor: H D, Colby, B, Abbott, M, Cachovic, K M, Debolt, B A, Mico

Publikováno v: Biochemical pharmacology. 49(8)

Recent investigations demonstrated that administration of 1-aminobenzotriazole (ABT) to rats caused adrenal gland enlargement. Studies were done to pursue the mechanism(s) involved. Preliminary experiments revealed that the adrenal enlargement caused

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::06def74764c6f4566cc6a16cae931afc
https://pubmed.ncbi.nlm.nih.gov/7748185

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