Zobrazeno 1 - 10
of 91
pro vyhledávání: '"K Lytle"'
Autor:
L. Paige Ferguson, Jovylyn Gatchalian, Matthew L. McDermott, Mari Nakamura, Kendall Chambers, Nirakar Rajbhandari, Nikki K. Lytle, Sara Brin Rosenthal, Michael Hamilton, Sonia Albini, Martin Wartenberg, Inti Zlobec, José A. Galván, Eva Karamitopoulou, Vera Vavinskaya, Alexis Wascher, Andrew M. Lowy, Christian M. Schürch, Pier Lorenzo Puri, Benoit G. Bruneau, Diana C. Hargreaves, Tannishtha Reya
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Clinical management of pancreatic cancer remains challenging. Here, the authors suggest SMARCD3 as a potential epigenetic dependency establishing the metabolic landscape in aggressive pancreatic cancer cells and as a potential therapeutic target in p
Externí odkaz:
https://doaj.org/article/eadb3f5725a947ddb9882b3a7d976ccc
Autor:
Vikas B. Gubbala, Nidhi Jytosana, Vincent Q. Trinh, H. Carlo Maurer, Razia F. Naeem, Nikki K. Lytle, Zhibo Ma, Steven Zhao, Wei Lin, Haiyong Han, Yu Shi, Tony Hunter, Pankaj K. Singh, Kenneth P. Olive, Marcus C.B. Tan, Susan M. Kaech, Geoffrey M. Wahl, Kathleen E. DelGiorno
Publikováno v:
Gastro Hep Advances, Vol 1, Iss 4, Pp 682-697 (2022)
Background and Aims: Eicosanoids, oxidized fatty acids that serve as cell-signaling molecules, have been broadly implicated in tumorigenesis. Here, we aimed to identify eicosanoids associated with pancreatic tumorigenesis and the cell types responsib
Externí odkaz:
https://doaj.org/article/feecc0f1541240d993d5e3ead6ccabdb
Publikováno v:
ACS Central Science, Vol 5, Iss 4, Pp 709-718 (2019)
Externí odkaz:
https://doaj.org/article/7febcbe7346e4d09a3c40e0a372ec32e
Autor:
Li-Wei Chang, Tyler K. Lytle, Mithun Radhakrishna, Jason J. Madinya, Jon Vélez, Charles E. Sing, Sarah L. Perry
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Monomer sequence is an emerging tool to precisely encode information (and thus structure and function) into polymer systems. Here the authors use sequence-control in complex coacervates to understand how monomer sequence translates to physical materi
Externí odkaz:
https://doaj.org/article/e963f99868cb41c18d48cd2798e8158f
Publikováno v:
J Caffeine Adenosine Res
Background: Lethal apnea is a significant cause of acute mortality following a severe traumatic brain injury (TBI). TBI is associated with a surge of adenosine, which also suppresses respiratory function in the brainstem. Methods and Materials: This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c3d6fffc8df9681cf52d6513a80fdd
https://doi.org/10.1089/caff.2019.0012
https://doi.org/10.1089/caff.2019.0012
Publikováno v:
Methods Mol Biol
Methods in Molecular Biology ISBN: 9781071621929
Methods in Molecular Biology ISBN: 9781071621929
Cancers are caricatures of normal development. Yet, for most organs we are only beginning to learn about the molecular events underlying the embryonic antecedents of organogenesis and when differentiation into the cell types found in the adult actual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c686eb239d41bc5923547d7d1876e32
https://europepmc.org/articles/PMC9663269/
https://europepmc.org/articles/PMC9663269/
Autor:
Anna L. Means, Charles J. Cho, Dylan T. Burnette, Olivia Ben-Levy, Geoffrey M. Wahl, Rajshekhar R. Giraddi, Vincent Q. Trinh, Uri Manor, Cynthia Ramos, Abigail C. Neininger, Kathleen E. DelGiorno, Sammy Weiser Novak, Jason C. Mills, Emilee A. Patterson, Ken S. Lau, Nikki K. Lytle, Zhibo Ma, Bob Chen, Leah Caplan, Marcus Tan, James R. Goldenring, Ichiro Matsumoto, Nidhi Jyotsana, Rafael Arrojo e Drigo
Publikováno v:
Gastroenterology
BACKGROUND & AIMSAcinar to ductal metaplasia (ADM) occurs in the pancreas in response to tissue injury and is a potential precursor for adenocarcinoma. The goal of these studies was to define the populations arising from ADM, the associated transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd3672fff60ad4a130ad5fa63b18199
https://europepmc.org/articles/PMC8792222/
https://europepmc.org/articles/PMC8792222/
Autor:
Ruijun Tian, Mathias Leblanc, Tony Pawson, Kathleen E. DelGiorno, Corina E. Antal, Yu Shi, Peiwu Huang, Elena Terenziani, Uri Manor, Michael A. Hollingsworth, Miriam Scadeng, Tony Hunter, Sarah E. Umetsu, Paul M. Grandgenett, Jill Meisenhelder, Galina Erikson, Timothy R. Donahue, Thom P. Santisakultarm, Ronald M. Evans, Xiao Yuan, Huaiyu Sun, Maya Ridinger-Saison, Geoffrey M. Wahl, Gyunghwi Woo, Daniel D. Von Hoff, Nikki K. Lytle, Andrew M. Lowy, Eric A. Collisson, Carlos Becerra, Linjing Fang, Michael Downes, Amanda M. Dann, Annette R. Atkins, Ruilian Xu, Weina Gao, Gaoyang Liang, Erkut Borazanci, Tannishtha Reya
Publikováno v:
Nature
Nature, vol 569, iss 7754
Nature, vol 569, iss 7754
Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis largely owing to inefficient diagnosis and tenacious drug resistance. Activation of pancreatic stellate cells (PSCs) and consequent development of dense stroma are prominent features acco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0a7b5ee93c1409b8565477bafb8c1f3
http://europepmc.org/articles/PMC6565370
http://europepmc.org/articles/PMC6565370
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e68324 (2013)
Axonal transport, a form of long-distance, bi-directional intracellular transport that occurs between the cell body and synaptic terminal, is critical in maintaining the function and viability of neurons. We have identified a requirement for the stat
Externí odkaz:
https://doaj.org/article/87e7eccf17e64e0495db889596ff0898
Autor:
Nikki K. Lytle, Hyog Young Kwon, Michael Hamilton, Jeevisha Bajaj, Ferdous Anower-E-Khuda, Tannishtha Reya, Mark H. Ginsberg, Jeffrey D. Esko, Bryan Zimdahl, Armin Ahmadi, Kyle R. Spinler, Joi Weeks, Jan Karlseder, Claire S. Koechlein, Marcie Kritzik, Hao Sun, Pyong Woo Park, Allen Blevins, Takahiro Ito
Publikováno v:
Nature communications, vol 11, iss 1
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Intratumoral heterogeneity is a common feature of many myeloid leukemias and a significant reason for treatment failure and relapse. Thus, identifying the cells responsible for residual disease and leukemia re-growth is critical to better understandi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d060c5584d0922de3b8568c04b179d6
https://escholarship.org/uc/item/7vk3p3vd
https://escholarship.org/uc/item/7vk3p3vd