Zobrazeno 1 - 10
of 200
pro vyhledávání: '"K Linnemann"'
Publikováno v:
Molecular Metabolism, Vol 78, Iss , Pp 101809- (2023)
Background: T1D is an autoimmune disease in which pancreatic islets of Langerhans are infiltrated by immune cells resulting in the specific destruction of insulin-producing islet beta cells. Our understanding of the factors leading to islet infiltrat
Externí odkaz:
https://doaj.org/article/739a8296cccc4b859cd972ef3d538867
Autor:
Simone Andresen, Selina K. Linnemann, Ahmad Burhani Ahmad Basri, Oleksandr Savysko, Christian Hamm
Publikováno v:
Biomimetics, Vol 9, Iss 2, p 85 (2024)
Diatoms have delicate and complex shells showing different lightweight design principles that have already been applied to technical products improving the mechanical properties. In addition, diatom inspired structures are expected to significantly a
Externí odkaz:
https://doaj.org/article/f49e20079b5e457d96268350f6437502
Publikováno v:
Biomimetics, Vol 9, Iss 1, p 46 (2024)
The intricate and highly complex morphologies of diatom frustules have long captured the attention of biomimetic researchers, initiating innovation in engineering solutions. This study investigates the potential of diatom-inspired surface stiffeners
Externí odkaz:
https://doaj.org/article/4ef1909ea58b4931b980b581ad3f0374
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Human islet transplantations into rodent models are an essential tool to aid in the development and testing of islet and cellular-based therapies for diabetes prevention and treatment. Through the ability to evaluate human islets in an in vivo settin
Externí odkaz:
https://doaj.org/article/37c49744422749848259dae60fd1ed89
Autor:
Julia Ast, Anastasia Arvaniti, Nicholas H. F. Fine, Daniela Nasteska, Fiona B. Ashford, Zania Stamataki, Zsombor Koszegi, Andrea Bacon, Ben J. Jones, Maria A. Lucey, Shugo Sasaki, Daniel I. Brierley, Benoit Hastoy, Alejandra Tomas, Giuseppe D’Agostino, Frank Reimann, Francis C. Lynn, Christopher A. Reissaus, Amelia K. Linnemann, Elisa D’Este, Davide Calebiro, Stefan Trapp, Kai Johnsson, Tom Podewin, Johannes Broichhagen, David J. Hodson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Glucagon-like peptide-1 receptor is an important regulator of appetite and glucose homeostasis. Here the authors describe super-resolution microscopy and in vivo imaging compatible fluorescent probes, which reveal endogenous glucagon-like peptide-1 r
Externí odkaz:
https://doaj.org/article/1bec881e08194ff3b4ad84658e067529
Autor:
Melissa T Adams, JaeAnn M Dwulet, Jennifer K Briggs, Christopher A Reissaus, Erli Jin, Joseph M Szulczewski, Melissa R Lyman, Sophia M Sdao, Vira Kravets, Sutichot D Nimkulrat, Suzanne M Ponik, Matthew J Merrins, Raghavendra G Mirmira, Amelia K Linnemann, Richard KP Benninger, Barak Blum
Publikováno v:
eLife, Vol 10 (2021)
The spatial architecture of the islets of Langerhans is hypothesized to facilitate synchronized insulin secretion among β cells, yet testing this in vivo in the intact pancreas is challenging. Robo βKO mice, in which the genes Robo1 and Robo2 are d
Externí odkaz:
https://doaj.org/article/6ffc13e7f9f7467bb80f8e6003960f0d
Autor:
K. Linnemann
Publikováno v:
Geographica Helvetica, Vol 74, Pp 167-181 (2019)
With their donation appeals aid organisations procure a polarised worldview of the self and other into our everyday lives and feed on discourses of “development” and “neediness”. This study investigates how the discourse of “development
Externí odkaz:
https://doaj.org/article/fd04b0655e344d7fafdf5ff1fd92c672
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/3e5cc5495bc7412f887eadc484a90f6b
Publikováno v:
Advances in Mechanical Engineering, Vol 12 (2020)
Finding the optimal structural design to avoid resonance has been a goal for decades. While recent applied methods often result in using additional active systems or higher mass, structural adaptation enables to shift eigenfrequencies without adding
Externí odkaz:
https://doaj.org/article/93f71a0d4d6e4360a63b956da2962e46
Autor:
Olha Melnyk, Charanya Muralidharan, Bryce E. Duffett, Alissa N. Novak, Glorian Perez-Aviles, Michelle M. Martinez, Justin J. Crowder, Amelia K. Linnemann
The catabolic pathway of autophagy is critical for pancreatic beta-cell function and is defective in established type 1 diabetes (T1D). However, it is unclear when and how this critical cell process becomes defective during diabetes pathogenesis. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1db9b65f7443fbb1bfea9dca85e12eb5
https://doi.org/10.1101/2023.05.23.541935
https://doi.org/10.1101/2023.05.23.541935
