Zobrazeno 1 - 10
of 136
pro vyhledávání: '"K Lasseter"'
Akademický článek
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Autor:
S Purohit, K Lasseter, Amit Gandhi, Derry C. Roopenian, Robert George Edward Holgate, Jonathan J. Hubbard, J E Humphries, L E Stolz, Jan Terje Andersen, Michal Pyzik, Atiya Mahmood, D de Graaf, Susan D. Jones, Arron Hearn, Alan J. Bitonti, J S Graydon, Richard S. Blumberg, K Kacena, Laurence J. Blumberg, Gregory J. Christianson, B Del Tito, L B Pearce, J. Cheung
Publikováno v:
Science Advances
Therapeutic blockade of FcRn in humans decreases IgG and IgG immune complex levels with the attendant immunologic implications.
The neonatal crystallizable fragment receptor (FcRn) functions as an intracellular protection receptor for immunoglob
The neonatal crystallizable fragment receptor (FcRn) functions as an intracellular protection receptor for immunoglob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7956be3e71940724cce8ce3634ea7a40
http://hdl.handle.net/10852/76135
http://hdl.handle.net/10852/76135
Autor:
M. Willett, Netanya S. Utay, K. Lasseter, P. F. Smith, W. Chang, M. Gottwald, Anoma Somasunderam, E. Lefebvre
Publikováno v:
Clinical and Translational Science
Cenicriviroc, a dual CCR2/CCR5 antagonist, is being evaluated for treatment of nonalcoholic steatohepatitis and liver fibrosis (CENTAUR; NCT02217475). As it is metabolized by the liver, cenicriviroc was investigated in hepatic-impaired participants f
Autor:
Kung Yee Liang, David Valle, Dimitri Avramopoulos, Ingo Ruczinski, Qing Li, Thomas A. Louis, M. Daniele Fallin, John A. McGrath, Ann E. Pulver, Virginia K. Lasseter, Paula S. Wolyniec
Publikováno v:
Genetic Epidemiology. 34:396-406
Schizophrenia (SZ) is a heritable and complex psychiatric disorder with an estimated worldwide prevalence of about 1%. Research on the risk factors for SZ has thus far yielded few clues to causes, but has pointed to a heterogeneous etiology that like
Publikováno v:
The Journal of Pain. 19:S74
Autor:
John A. McGrath, M. D. Fallin, A. E. Pulver, Virginia K. Lasseter, Jennifer G. Mulle, Paula S. Wolyniec
Publikováno v:
Molecular Psychiatry. 12:367-375
Parent-of-origin effects have been implicated as mediators of genetic susceptibility for a number of complex disease phenotypes, including bipolar disorder. Specifically, evidence for linkage on chromosome 18 is modified when allelic parent-of-origin
Autor:
Ann E. Pulver, David Valle, Paula S. Wolyniec, Virginia K. Lasseter, John A. McGrath, Kung Yee Liang, M. Daniele Fallin, Gerald Nestadt
Publikováno v:
The American Journal of Human Genetics. 75(2):204-219
The relatively short history of linkage studies in bipolar disorders (BPs) has produced inconsistent findings. Implicated regions have been large, with reduced levels of significance and modest effect sizes. Both phenotypic and genetic heterogeneity
Akademický článek
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Autor:
Virginia K. Lasseter, Y F Chiu, Paula S. Wolyniec, Karen Swartz, A. E. Pulver, Mary H. Thornquist, John A. McGrath, Gerald Nestadt, Kung-Yee Liang
Publikováno v:
Molecular Psychiatry. 7:658-664
Information from multiple genome scans and collaborative efforts suggests that schizophrenia is a heterogeneous, complex disorder with polygenic and environmental antecedents. In a previous paper we demonstrated that stratification of families on the
Autor:
Virginia K. Lasseter, Haig H. Kazazian, Stylianos E. Antonarakis, Paula S. Wolyniec, David E. Housman, Mary H. Thornquist, Beth A. Dombroski, Jean-Louis Blouin, Kung-Yee Liang, John A. McGrath, A. E. Pulver, Karen Swartz, Jennifer G. Mulle, Gerald Nestadt
Publikováno v:
Molecular Psychiatry, Vol. 5, No 6 (2000) pp. 650-653
Scopus-Elsevier
Scopus-Elsevier
Despite considerable effort to identify susceptibility loci for schizophrenia, none have been localized. Multiple genome scans and collaborative efforts have shown evidence for linkage to regions on chromosomes 1q, 5q, 6q, 8p, 13q, 10p and 22q.(1-9)