Zobrazeno 1 - 10
of 157
pro vyhledávání: '"K Lambe"'
Autor:
Jonas Rybnicek, Yuxiao Chen, Milos Milic, Earvin S. Tio, JoAnne McLaurin, Timothy J. Hohman, Philip L. De Jager, Julie A. Schneider, Yanling Wang, David A. Bennett, Shreejoy Tripathy, Daniel Felsky, Evelyn K. Lambe
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Changes in high-affinity nicotinic acetylcholine receptors are intricately connected to neuropathology in Alzheimer’s Disease (AD). Protective and cognitive-enhancing roles for the nicotinic α5 subunit have been identified, but this gene
Externí odkaz:
https://doaj.org/article/f374cbbc47054ea0a3ea6f1c0e8deae1
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108824- (2024)
Summary: Associating contexts with rewards depends on hippocampal circuits, with local inhibitory interneurons positioned to play an important role in shaping activity. Here, we demonstrate that the encoding of context-reward memory requires a ventra
Externí odkaz:
https://doaj.org/article/8f75e94a077c4b24a22ca007debd6a98
Autor:
K. Lambe, S. Guerra, G. Salazar de Pablo, S. Ayis, I. D. Cameron, N. E. Foster, E. Godfrey, C. L. Gregson, F. C. Martin, C. Sackley, N. Walsh, K. J. Sheehan
Publikováno v:
BMC Geriatrics, Vol 22, Iss 1, Pp 1-18 (2022)
Abstract Background To synthesise the evidence for the effectiveness of inpatient rehabilitation treatment ingredients (versus any comparison) on functioning, quality of life, length of stay, discharge destination, and mortality among older adults wi
Externí odkaz:
https://doaj.org/article/dcc28db5dcfe4ae895d861b98ecbc8c4
Autor:
Sridevi Venkatesan, Tianhui Chen, Yupeng Liu, Eric E. Turner, Shreejoy J. Tripathy, Evelyn K. Lambe
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105992- (2023)
Summary: Attention depends on cholinergic excitation of prefrontal neurons but is sensitive to perturbation of α5-containing nicotinic receptors encoded by Chrna5. However, Chrna5-expressing (Chrna5+) neurons remain enigmatic, despite their potentia
Externí odkaz:
https://doaj.org/article/938146cb44344155b648b41bc1833e9a
Publikováno v:
BMC Geriatrics, Vol 21, Iss 1, Pp 1-15 (2021)
Abstract Background Patients with hip fracture and depression are less likely to recover functional ability. This review sought to identify prognostic factors of depression or depressive symptoms up to 1 year after hip fracture surgery in adults. Thi
Externí odkaz:
https://doaj.org/article/cf0ca8ce049d491da58c9cc001445e56
SUMMARYAssociating contexts with rewards depends on hippocampal circuits, with local inhibitory interneurons positioned to play an important role in shaping activity. Here, we hypothesize that the encoding of context-reward memory requires a ventral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8daa2a9d8f790e7351d1723432292c04
https://doi.org/10.1101/2023.04.27.538595
https://doi.org/10.1101/2023.04.27.538595
Autor:
Ashlea A. Morgan, Nuno D. Alves, Gregory S. Stevens, Tamanna T. Yeasmin, Alexandra Mackay, Saige Power, Derya Sargin, Carla Hanna, Arwa L. Adib, Annette Ziolkowski-Blake, Evelyn K. Lambe, Mark S. Ansorge
Publikováno v:
bioRxiv
The medial prefrontal cortex (mPFC) regulates cognitive flexibility and emotional behavior. Neurons that release serotonin project to the mPFC, and serotonergic drugs influence emotion and cognition. Yet, the specific roles of endogenous serotonin re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a73827ec9515913085af7e13d7e84b
https://europepmc.org/articles/PMC10081203/
https://europepmc.org/articles/PMC10081203/
Autor:
Daniel W. Sparks, Michael K. Tian, Derya Sargin, Sridevi Venkatesan, Katheron Intson, Evelyn K. Lambe
Publikováno v:
Frontiers in Neural Circuits, Vol 11 (2018)
Prefrontal cortex is a hub for attention processing and receives abundant innervation from cholinergic and serotonergic afferents. A growing body of evidence suggests that acetylcholine (ACh) and serotonin (5-HT) have opposing influences on tasks req
Externí odkaz:
https://doaj.org/article/dc7ad6c3c9f640d7be4510dd297bfc8d
Autor:
Jonas Rybnicek, Yuxiao Chen, Milos Milic, JoAnne McLaurin, Phillip De Jager, Julie A Schneider, Yanling Wang, David A Bennett, Shreejoy Tripathy, Daniel Felsky, Evelyn K Lambe
Changes in high-affinity nicotinic acetylcholine receptors are intricately connected to neuropathology in Alzheimer's Disease (AD). Protective and cognitive-enhancing roles for the nicotinic α5 subunit have been identified, but this gene has not bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4662afbb7e13521f8b07b6c3fad07a63
https://doi.org/10.1101/2022.05.03.490491
https://doi.org/10.1101/2022.05.03.490491
Publikováno v:
eLife, Vol 5 (2016)
The activity of serotonin (5-HT) neurons is critical for mood regulation. In a mouse model of chronic social isolation, a known risk factor for depressive illness, we show that 5-HT neurons in the dorsal raphe nucleus are less responsive to stimulati
Externí odkaz:
https://doaj.org/article/d4f625d8ad2f4c76850be009c1bb38cd