Zobrazeno 1 - 10 of 14 pro vyhledávání: '"K L Servis"'
1
Proton magnetic resonance studies of the decomposition of 4-hydroxycyclophosphamide, a microsomal metabolite of cyclophosphamide
Autor: E J, Valente, K K, Chan, K L, Servis
Publikováno v: Pharmaceutical research. 1(2)
The proposed tautomeric equilibrium between the microsomal metabolite of cyclophosphamide, 4-hydroxycyclophosphamide, and the open chain aldophosphamide, and the subsequent facile β-elimination to generate acrolein and phosphoramide mustard have bee
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bb40128a7b4df5d3175f8088ad777820
https://pubmed.ncbi.nlm.nih.gov/24277218
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2
Human tumor fluorouracil trapping: clinical correlations of in vivo 19F nuclear magnetic resonance spectroscopy pharmacokinetics
Autor: Walter Wolf, R L Ong, Dennis J. Atkinson, K L Servis, M J Albright, Charles L. Wiseman, Cary A. Presant, Douglas W. Blayney, R Ring, M King
Publikováno v: Journal of Clinical Oncology. 8:1868-1873
We previously reported that fluorouracil (5FU) accumulation and metabolism in human livers and tumors can be studied by in vivo nuclear magnetic resonance spectroscopy (NMRS). We have extended these observations by evaluating the pharmacokinetics of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f5e7ebde0fc7b25998b8a44aa1a659
https://doi.org/10.1200/jco.1990.8.11.1868
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3
Effect of intravenous epinephrine on serum magnesium and free intracellular red blood cell magnesium concentrations measured by nuclear magnetic resonance
Autor: K L Servis, E Ryzen, Robert K. Rude
Publikováno v: Journal of the American College of Nutrition. 9:114-119
Hypomagnesemia is a common clinical finding in hospitalized patients and can cause hypocalcemia, cardiac arrhythmias, muscular weakness, and hypokalemia. Hypomagnesemia usually implies cellular magnesium (Mg) depletion, but stress and some clinical c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6294deb4c3f2992edf8b36849aad2ef
https://doi.org/10.1080/07315724.1990.10720359
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4
Tumor trapping of 5-fluorouracil: in vivo 19F NMR spectroscopic pharmacokinetics in tumor-bearing humans and rabbits
Autor: Dennis J. Atkinson, A el-Tahtawy, R L Ong, M King, K L Servis, Walter Wolf, M J Albright, C A Presant, rd R Ring, P B Barker
Publikováno v: Proceedings of the National Academy of Sciences. 87:492-496
The pharmacokinetics of 5-fluorouracil (5FU) were studied in vivo in patients with discrete tumors and in rabbits bearing VX2 tumors by using 19F NMR spectroscopy. The human studies were conducted in a 1.5-T Magnetom magnetic resonance imager (Siemen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d09a2c6aeea6594ad750d970bfdebd6
https://doi.org/10.1073/pnas.87.1.492
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8
Determination of intracellular free magnesium by nuclear magnetic resonance in human magnesium deficiency
Autor: P DeRusso, A Kershaw, Robert K. Rude, T Stephen, K L Servis, E Ryzen
Publikováno v: Journal of the American College of Nutrition. 8(6)
Magnesium (Mg) deficiency is a common clinical problem. As Mg is predominantly an intracellular cation and Mg deficiency may exist despite normal serum Mg (sMg) concentrations, we have utilized nuclear magnetic resonance (NMR) techniques in an attemp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb5e587ca9e6894dfdd6e20ef7ec498
https://pubmed.ncbi.nlm.nih.gov/2621295
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