Výsledky vyhledávání

Confirmation rate of cell free DNA screening for sex chromosomal abnormalities according to the method of confirmatory testing

Autor: K. Lüthgens, Francesca Romana Grati, Karina Häbig, Karl Oliver Kagan, Monika Sinzel

Publikováno v: Prenatal diagnosisREFERENCES. 41(10)

Objective To examine the positive predictive value (PPV) of cfDNA screening for sex chromosome aneuploidies (SCA) in a large series of over 90 000 patients. Methods Retrospective study based on samples that were sent to Cenata, a private laboratory w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c91ca0c6f91421b671c70c0d95bd3ba
https://pubmed.ncbi.nlm.nih.gov/32804406

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First-trimester risk assessment based on ultrasound and cell-free DNAvscombined screening: a randomized controlled trial

Autor: Jiri Sonek, Harald Abele, Fabrina Sroka, Sara Y. Brucker, Markus Hoopmann, Diethelm Wallwiener, Philipp Wagner, Karl Oliver Kagan, K. Lüthgens, Maximilian Schmid

Publikováno v: Ultrasound in Obstetrics & Gynecology. 51:437-444

Objective Prospective randomized trial to compare the performance of first trimester combined screening (FTCS) with an approach that uses the combination of a detailed ultrasound examination and cfDNA analysis. Methods Pregnant women with a normal fi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b149085adf872374be3128d6493d3d9
https://doi.org/10.1002/uog.18905

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Akademický článek

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False-Positive Rate in First-Trimester Screening Based on Ultrasound and Cell-Free DNA versus First-Trimester Combined Screening with Additional Ultrasound Markers

Autor: Maximilian Schmid, Karl Oliver Kagan, Jiri Sonek, K. Lüthgens, Markus Hoopmann, Philipp Wagner, Vanessa Maier, Harald Abele

Publikováno v: Fetal diagnosis and therapy. 45(5)

Objective: To determine whether screening for trisomy 21 based on first-trimester combined screening (FTCS) with assessment of nasal bone (NB), tricuspid flow (TCF), and ductus venosus flow (DVF) results in similar false-positive rates compared to ul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35055b8db8808acc2226b55f6cc506ce
https://pubmed.ncbi.nlm.nih.gov/29940565

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Comment on 'The importance of determining the limit of detection of non-invasive prenatal testing methods'

Autor: K. Lüthgens, Andreas Binder, Dirk Biskup

Publikováno v: Prenatal diagnosis. 36(9)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9371eb85d6593840e526e464e84276c
https://pubmed.ncbi.nlm.nih.gov/27612151

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[Diverging detection limits of immunochemical tests for occult blood underline the necessity of standardization and quality assurance]

Autor: K, Lüthgens, S, Albert, H, Brenner

Publikováno v: Zeitschrift fur Gastroenterologie. 54(4)

Immunological fecal occult blood tests (FIT) are superior in detecting colorectal cancer and its precursors compared to conventional Guajac-based tests. Besides quantitative, laboratory-based FITs qualitative, office-based FITs are increasingly emplo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a5f99a1c84454aa630b9b4e9fda0567d
https://pubmed.ncbi.nlm.nih.gov/27056457

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First-trimester combined screening for trisomy 21 with different combinations of placental growth factor, free β-human chorionic gonadotropin and pregnancy-associated plasma protein-A

Autor: R. Alkier, K. Lüthgens, Harald Abele, Karl O. Kagan, Markus Hoopmann

Publikováno v: Ultrasound in Obstetrics & Gynecology. 40:530-535

Objective To examine placental growth factor (PlGF) in euploid and trisomy 21 pregnancies at 11–13 weeks' gestation and to model the impact on first-trimester combined screening. Methods PlGF was measured in 509 (409 euploid and 100 trisomic) fetal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1055824a6bd4dfcc4f3aa1b753645df1
https://doi.org/10.1002/uog.11173

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Comparison of Three First Trimester Screening Algorithms for Trisomy 21 with and without Adjustment for Maternal Characteristics

Autor: B. J. Hackelöer, C. Thode, K. Lüthgens, B. Eiben, Karl Oliver Kagan, E. Merz

Publikováno v: Ultraschall in der Medizin - European Journal of Ultrasound. 34:151-156

Purpose: Comparison of three algorithms (DoE 2007 and DoE 2011 algorithm of the FMF Germany and MoM algorithm of the FMF UK) in first trimester biochemical screening for trisomy 21 based on maternal and gestational age, free s-hCG, and PAPP-A and ass

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337baf25eeeb7062a39225afaabe4d8e
https://doi.org/10.1055/s-0032-1312954

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Screening auf Trisomie 18 und Trisomie 13 durch das kombinierte Anwenden der Risiko-Algorithmen für Trisomie 21, 18 und 13

Autor: Harald Abele, K. Lüthgens, B. Yazdi, Karl O. Kagan, Markus Hoopmann, R. Alkier

Publikováno v: Ultraschall in der Medizin - European Journal of Ultrasound. 33:E57-E61

Ziel: Beurteilung der Testgute des kombinierten Ersttrimester-Screenings auf Trisomien 18 und 13 bei gemeinsamer Verwendung der Risikoalgorithmen fur Trisomie 21, 18 und 13 in einem deutschen Patientenkollektiv. Material und Methoden: Bei 39 004 Schw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d55a10a6e59b3524300d49500afe5383
https://doi.org/10.1055/s-0031-1299083

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