Zobrazeno 1 - 7
of 7
pro vyhledávání: '"K L, Mohlke"'
Publikováno v:
Pediatric obesity. 8(5)
Age of menarche, or the timing of first menses in girls, is a physiological trait that shows substantial genetic heritability. Earlier age of menarche is associated with increased childhood adiposity and with adult risk of obesity and cardiovascular
Autor:
M, Graff, K E, North, A S, Richardson, K M, Young, K L, Mohlke, L A, Lange, E M, Lange, K M, Harris, P, Gordon-Larsen
Publikováno v:
Pediatric obesity. 8(6)
There has been little investigation of gene-by-environment interactions related to sedentary behaviour, a risk factor for obesity defined as leisure screen time (ST; i.e. television, video and computer games).To test the hypothesis that limiting ST u
Autor:
William C. Nichols, RT Swank, JD Ballew, KA Cooney, K. L. Mohlke, M Reddington, EK Novak, ME Bruck, A Yang, David Ginsburg
Publikováno v:
Blood. 83:3225-3231
An animal model for human type I von Willebrand disease (vWD) has been previously described in the inbred mouse strain RIIIS/J. Murine vWD is characterized by a prolonged bleeding time, normal von Willebrand factor (vWF) multimer distribution, autoso
Autor:
Juan M. Bilbao, Lorne Zinman, Janice Robertson, Karen E. Morrison, Danielle Moreno, H. N. Liu, K. L. Mohlke, Christine Sato, A. F. Marvelle, Yosuke Wakutani, Ekaterina Rogaeva
Background: About 20% of familial amyotrophic lateral sclerosis (ALS) is caused by mutations in SOD1 and is typically transmitted as an autosomal dominant trait. However, due to reduced mutation penetrance, the disease may present in a recessive or s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ef74063bd4ccfb3e096ca9fc5c9a53
https://europepmc.org/articles/PMC2680064/
https://europepmc.org/articles/PMC2680064/
Autor:
J A, Douglas, M R, Erdos, R M, Watanabe, A, Braun, C L, Johnston, P, Oeth, K L, Mohlke, T T, Valle, C, Ehnholm, T A, Buchanan, R N, Bergman, F S, Collins, M, Boehnke, J, Tuomilehto
Publikováno v:
Diabetes. 50(4)
Recent studies have identified a common proline-to-alanine substitution (Pro12Ala) in the peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2), a nuclear receptor that regulates adipocyte differentiation and possibly insulin sensitivity. T
Autor:
S, Ghosh, R M, Watanabe, T T, Valle, E R, Hauser, V L, Magnuson, C D, Langefeld, D S, Ally, K L, Mohlke, K, Silander, K, Kohtamäki, P, Chines, J, Balow, G, Birznieks, J, Chang, W, Eldridge, M R, Erdos, Z E, Karanjawala, J I, Knapp, K, Kudelko, C, Martin, A, Morales-Mena, A, Musick, T, Musick, C, Pfahl, R, Porter, J B, Rayman
Publikováno v:
American journal of human genetics. 67(5)
We performed a genome scan at an average resolution of 8 cM in 719 Finnish sib pairs with type 2 diabetes. Our strongest results are for chromosome 20, where we observe a weighted maximum LOD score (MLS) of 2.15 at map position 69.5 cM from pter and
Autor:
W C, Nichols, K A, Cooney, K L, Mohlke, J D, Ballew, A, Yang, M E, Bruck, M, Reddington, E K, Novak, R T, Swank, D, Ginsburg
Publikováno v:
Blood. 83(11)
An animal model for human type I von Willebrand disease (vWD) has been previously described in the inbred mouse strain RIIIS/J. Murine vWD is characterized by a prolonged bleeding time, normal von Willebrand factor (vWF) multimer distribution, autoso