Zobrazeno 1 - 10
of 198
pro vyhledávání: '"K L, Lunetta"'
Autor:
J E Siland, B Geelhoed, C Roselli, B Wang, H J Lin, S Weiss, S Trompet, M E van den Berg, E Z Soliman, L Y Chen, I Ford, J W Jukema, P W Macfarlane, J Kornej, H Lin, K L Lunetta, M Kavousi, J A Kors, M A Ikram, X Guo, J Yao, M Dörr, S B Felix, U Völker, N Sotoodehnia, D E Arking, B H Stricker, S R Heckbert, S A Lubitz, E J Benjamin, A Alonso, P T Ellinor, P van der Harst, M Rienstra
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0268768 (2022)
BackgroundBoth elevated and low resting heart rates are associated with atrial fibrillation (AF), suggesting a U-shaped relationship. However, evidence for a U-shaped causal association between genetically-determined resting heart rate and incident A
Externí odkaz:
https://doaj.org/article/ac9d5b0f7c084fa48d7e8ef72647886a
Autor:
Jirong Long, Nora Franceschini, Charles Kooperberg, Eric Boerwinkle, Julie R. Palmer, Laura M. Raffield, Guochong Jia, Lindsay Fernández-Rhodes, Wei Zheng, K. L. Lunetta, Tamar Sofer, Robert B. Wallace, Diana L. Cousminer, Quenna Wong, Joanne M. Murabito, Leslie A. Lange, Babette S. Zemel, Struan F.A. Grant, Ran Tao, Chloé Sarnowski, Jonathan P. Bradfield, Gary Zirpoli, Kari E. North, Hakon Hakonarson, Adolfo Correa
Publikováno v:
Hum Reprod
STUDY QUESTIONDoes the expansion of genome-wide association studies (GWAS) to a broader range of ancestries improve the ability to identify and generalise variants associated with age at menarche (AAM) in European populations to a wider range of worl
Autor:
Schellenberg Gd, Haines Jl, K. L. Lunetta, Lindsay A. Farrer, Gaoyuan Meng, Yang You, Jaeyoon Chung, Tatiana Foroud, Richard Mayeux, Tsuneya Ikezu, David A. Bennett, Li-San Wang, Rhoda Au, Margaret A. Pericak-Vance, Junming Hu, Congcong Zhu, Rebecca Panitch, Weiming Xia, Gyungah Jun, Thor D. Stein
BackgroundRecent reports suggest that the rare apolipoprotein E (APOE) Christchurch mutation and ε2 allele protect against Alzheimer’s disease (AD) pathology by reducing the burden of tau pathology. However, the mechanism(s) underlying the ε2 pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12271ba8174512e10930dd6cef81dc0c
https://doi.org/10.1101/2020.11.20.20235051
https://doi.org/10.1101/2020.11.20.20235051
Autor:
Johan G. Eriksson, Ayse Demirkan, Francesco Cucca, Hanna Ollila, Klaus Berger, A.G. Uitterlinden, Sharon L.R. Kardia, Yongmei Liu, Veikko Salomaa, W. V. Zhuang, Antonio Terracciano, Nese Direk, Osorio Meirelles, K. L. Lunetta, Myriam Fornage, Jennifer A. Smith, Lei Yu, Karin Hek, Aarno Palotie, Elisabeth Widen, Karestan C. Koenen, Thomas H. Mosley, Jürgen Wellmann, Markus Perola, Wei Zhao, Luigi Ferrucci, Kristine Yaffe, C M van Duijn, A. Hofman, Angelina R. Sutin, Aaron Isaacs, Jessica D. Faul, Paul Lichtenstein, Mike A. Nalls, Patrik K. E. Magnusson, Ben A. Oostra, Alexander Viktorin, Anna Murray, Jari Lahti, Mikael Landén, Joanne M. Murabito, David R. Weir, Toshiko Tanaka, Nancy L. Pedersen, Jun Ding, Luke C. Pilling, David A. Bennett, Tiina Paunio, Alan B. Zonderman, Marilyn C. Cornelis, Fernando Rivadeneira, David J. Llewellyn, Henning Tiemeier, Katri Räikkönen, Annemarie I. Luik, Antonella Mulas, Tamara B. Harris
Publikováno v:
Psychological Medicine, 46(8), 1613-1623. Cambridge University Press
BackgroundMajor depressive disorder (MDD) is moderately heritable, however genome-wide association studies (GWAS) for MDD, as well as for related continuous outcomes, have not shown consistent results. Attempts to elucidate the genetic basis of MDD m
Autor:
K. L. Lunetta, Shalender Bhasin, David Karasik, Douglas P. Kiel, Wei V. Zhuang, Thomas G. Travison, Joanne M. Murabito, Andrea D. Coviello
Publikováno v:
Clinical Endocrinology. 80:277-282
SummaryObjective Circulating testosterone, oestradiol and oestrone concentrations vary considerably between men. Although a substantial proportion of this variation may be attributed to morbidity and behavioural factors, these cannot account for its
Autor:
K. L. Lunetta, C.M. van Duijn, A.G. Uitterlinden, Stefania Bandinelli, Linda Broer, A. M. Arnold, Yongmei Liu, Marcus Dörr, Joanne M. Murabito, W. Hoffmann, Toshiko Tanaka, Thomas Kocher, Albert Hofman, Ellen W. Demerath, Albert V. Smith, Jerome I. Rotter, David Karasik, Bruce M. Psaty, Vilmundur Gudnason, Robert C. Kaplan, Ben A. Oostra, Kurt Lohman, Lenore J. Launer, G. J. Tranah, Luigi Ferrucci, S. Walter, H. Wallaschofski, M. E. Garcia, Nora Franceschini, Henning Tiemeier, Tamara B. Harris, Douglas P. Kiel, Gil Atzmon, G. Homuth, A.B. Newman
Publikováno v:
Age, 35(4), 1367-1376. Springer International Publishing AG
Age
Age
Experimental mild heat shock is widely known as an intervention that results in extended longevity in various models along the evolutionary lineage. Heat shock proteins (HSPs) are highly upregulated immediately after a heat shock. The elevation in HS
Autor:
Richard C. Green, Mark W. Logue, Charles DeCarli, Holly Posner, Heng Zou, Stephen W. Hurt, L. Adrienne Cupples, Lindsay A. Farrer, Margaret Moline, K. L. Lunetta
Publikováno v:
Alzheimer's & Dementia. 7:493-500
Background Recent pathological studies report vascular pathology in clinically diagnosed Alzheimer's disease (AD) and AD pathology in clinically diagnosed vascular dementia (VaD). We compared magnetic resonance imaging (MRI) measures of vascular brai
Autor:
L. A. Cupples, K. L. Lunetta, Robert C. Green, Stefan Wagenpfeil, Charles DeCarli, Robert Perneczky, Lindsay A. Farrer, Alexander Kurz
Publikováno v:
Neurology. 75:137-142
Background: Clinical and epidemiologic studies suggest that patients with Alzheimer disease (AD) with larger head circumference have better cognitive performance at the same level of brain pathology than subjects with smaller head circumference.Metho
Autor:
Wang, Yajie1 (AUTHOR), Yang, Yuting1 (AUTHOR), Cai, Ying1 (AUTHOR), Aobulikasimu, Ayikaimaier1 (AUTHOR), Wang, Yuexin1 (AUTHOR), Hu, Chuanwei1 (AUTHOR), Miao, Zhikang1 (AUTHOR), Shao, Yue1 (AUTHOR), Zhao, Mengna1 (AUTHOR), Hu, Yue1 (AUTHOR), Xu, Chang1 (AUTHOR), Chen, Xinjun2 (AUTHOR), Li, Zhiqiang2 (AUTHOR), Chen, Jincao2 (AUTHOR), Wang, Lianrong1,3 (AUTHOR) lianrong2008@gmail.com, Chen, Shi1,4 (AUTHOR) shichen@whu.edu.cn
Publikováno v:
Advanced Science. 11/6/2024, Vol. 11 Issue 41, p1-18. 18p.
Autor:
Molavi Vasei, Farnoosh1 (AUTHOR), Zamanian, Mohammad Yasin2,3 (AUTHOR), Golmohammadi, Maryam4 (AUTHOR), Mahmoodi, Mehdi5 (AUTHOR), Khademalhosseini, Morteza6 (AUTHOR), Tavakoli, Tayyebeh7 (AUTHOR), Esmaeili, Ozra Sadat1 (AUTHOR), Zarei, Sadegh1 (AUTHOR), Reza Mirzaei, Mohammad1 (AUTHOR), Hajizadeh, Mohammad Reza1 (AUTHOR) hajizadehus@yahoo.com
Publikováno v:
Food Science & Nutrition. Nov2024, Vol. 12 Issue 11, p9834-9845. 12p.