Zobrazeno 1 - 10
of 22
pro vyhledávání: '"K L, Komschlies"'
Publikováno v:
Blood. 88:4139-4148
Administration of recombinant human interleukin-7 (rhIL-7) to mice increases the exportation of myeloid progenitors (colony-forming unit [CFU]-c and CFU-granulocyte erythroid megakaryocyte macrophage [CFU-GEMM]) from the bone marrow (BM) to periphera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ae238aff3fd361a4f9e25e3eee4ae3
https://doi.org/10.1182/blood.v88.11.4139.bloodjournal88114139
https://doi.org/10.1182/blood.v88.11.4139.bloodjournal88114139
Autor:
F. W. Ruscetti, K. L. Komschlies, Sten Eirik W. Jacobsen, Robert H. Wiltrout, Jonathan R. Keller, Krzysztof J. Grzegorzewski
Publikováno v:
The Journal of Experimental Medicine
Administration of recombinant human interleukin 7 (rh)IL-7 to mice has been reported by our group to increase the exportation of myeloid progenitors (colony-forming unit [CFU]-c and CFU-granulocyte erythroid megakarocyte macrophage) from the bone mar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fb56a39f482533523d2c927e114a854
http://europepmc.org/articles/PMC2191845
http://europepmc.org/articles/PMC2191845
Publikováno v:
The Journal of Immunology. 152:5776-5784
These studies investigate the effects of exogenously administered recombinant human IL-7 (rhIL-7) on mouse leukocyte subsets in vivo in normal and tumor-bearing mice. The administration of rhIL-7 to normal mice caused a pronounced leukocytosis (three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec20d21e0d713f799a4f7bf22cfc3bfd
https://doi.org/10.4049/jimmunol.152.12.5776
https://doi.org/10.4049/jimmunol.152.12.5776
Publikováno v:
In vivo (Athens, Greece). 15(4)
A significant splenomegaly and lymphadenopathy develops during the progressive growth of Lewis Lung (3LL) tumors in mice. Enlarged spleen and lymph nodes occur because of a pronounced increase in granulocytes in these organs. This granulocytosis in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2a5394b9ab40ebe133f2df151ce5e0f
https://pubmed.ncbi.nlm.nih.gov/11695215
https://pubmed.ncbi.nlm.nih.gov/11695215
Autor:
J M, Wigginton, E, Gruys, L, Geiselhart, J, Subleski, K L, Komschlies, J W, Park, T A, Wiltrout, K, Nagashima, T C, Back, R H, Wiltrout
Publikováno v:
The Journal of clinical investigation. 108(1)
Systemic administration of IL-12 and intermittent doses of IL-2 induce complete regression of metastatic murine renal carcinoma. Here, we show that overt tumor regression induced by IL-12/pulse IL-2 is preceded by recruitment of CD8(+) T cells, vascu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c64a5e49dc80509a50367b5b959efdb
https://pubmed.ncbi.nlm.nih.gov/11435457
https://pubmed.ncbi.nlm.nih.gov/11435457
Autor:
T J, Sayers, A D, Brooks, J K, Lee, R G, Fenton, K L, Komschlies, J M, Wigginton, R, Winkler-Pickett, R H, Wiltrout
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(8)
Mice bearing the experimental murine renal cancer Renca can be successfully treated with some forms of immunotherapy. In the present study, we have investigated the molecular pathways used by NK and T cells to lyse Renca cells. Renca cells normally e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7c4117ad1fbbf1b691bb59d61510e8b
https://pubmed.ncbi.nlm.nih.gov/9780164
https://pubmed.ncbi.nlm.nih.gov/9780164
Autor:
H A, Young, D M, Klinman, D A, Reynolds, K J, Grzegorzewski, A, Nii, J M, Ward, R T, Winkler-Pickett, J R, Ortaldo, J J, Kenny, K L, Komschlies
Publikováno v:
Blood. 89(2)
Interferon-gamma (IFN-gamma) is an immunoregulatory lymphokine that is primarily produced by T cells and natural killer cells. It has effects on T-cell, B-cell, and macrophage differentiation and maturation. We have developed transgenic mice that exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce310d8644b3c434747a9f4ecd0413a0
https://pubmed.ncbi.nlm.nih.gov/9002962
https://pubmed.ncbi.nlm.nih.gov/9002962
Autor:
J L, Franco, P, Ghosh, R H, Wiltrout, C R, Carter, A H, Zea, N, Momozaki, A C, Ochoa, D L, Longo, T J, Sayers, K L, Komschlies
Publikováno v:
Cancer research. 55(17)
Flavone-8-acetic acid plus recombinant human interleukin 2 is a successful antitumor therapy in mice bearing the Renca murine renal cell carcinoma. This report demonstrates that T cells, particularly CD8+ T cells, are critical for the generation of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c59809d7db4702beb4cfb2442a5ea9d
https://pubmed.ncbi.nlm.nih.gov/7641202
https://pubmed.ncbi.nlm.nih.gov/7641202
Autor:
R H, Wiltrout, T A, Gregorio, R G, Fenton, D L, Longo, P, Ghosh, W J, Murphy, K L, Komschlies
Publikováno v:
Seminars in oncology. 22(1)
Antigen-nonspecific approaches to the use of BRMs for cancer treatment have resulted in only limited success to date. In particular, the use of large numbers of adoptively transferred, broadly cytotoxic LAK cells in combination with IL-2 has been eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6f4bab17999b7e88a4767dddf2f1434d
https://pubmed.ncbi.nlm.nih.gov/7855624
https://pubmed.ncbi.nlm.nih.gov/7855624
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(12)
These studies investigate the effects of exogenously administered recombinant human IL-7 (rhIL-7) on mouse leukocyte subsets in vivo in normal and tumor-bearing mice. The administration of rhIL-7 to normal mice caused a pronounced leukocytosis (three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4efb7f6a275038dfdc9b082a3070e196
https://pubmed.ncbi.nlm.nih.gov/8207207
https://pubmed.ncbi.nlm.nih.gov/8207207