Zobrazeno 1 - 10
of 24
pro vyhledávání: '"K L, Clay"'
Publikováno v:
Journal of Lipid Research, Vol 28, Iss 1, Pp 42-49 (1986)
Two physicochemical methods have been developed for the quantitative analysis of lyso-platelet activating factor (lyso-PAF) based on gas-liquid chromatography-mass spectrometry (GLC/MS) and fast atom bombardment-mass spectrometry (FAB/MS) using stabl
Externí odkaz:
https://doaj.org/article/0efc962255e84c1fb26af131593cc648
Autor:
Demokritos C. Tsoukatos, T Liapikos, Robert C. Murphy, Ewa Ninio, M. Arborati, MJ Chapman, K L Clay
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 17:3505-3512
Abstract Free radical-mediated oxidation of cholesterol-rich LDL plays a key role in atherogenesis and involves the formation of oxidized phospholipids with proinflammatory biological activity. We evaluated the production of platelet-activating facto
Publikováno v:
The Journal of Immunology. 155:5819-5825
The specific recognition of phosphatidylserine (PS) by macrophages is believed to be one means by which effete and apoptotic cells expressing PS on their outer membrane leaflet are targeted for phagocytosis. The aim of this study was to better unders
Publikováno v:
The Journal of Immunology. 152:566-573
Based on previous data which demonstrated the ability of platelet-activating factor (PAF) antagonists to inhibit constitutive immunoglobulin synthesis in B-lymphoblastoid cell lines, we determined the capacity of these cells to synthesize PAF or 1-pa
Autor:
K. L. Clay, R. C. Murphy
Publikováno v:
ChemInform. 22
Publikováno v:
The Journal of Immunology. 148:514-523
Recent studies suggest that cellular internalization of platelet-activating factor (PAF), a potent ether phospholipid mediator of inflammation, is modulated by, as yet undefined cellular mechanisms. Using an albumin extraction method, the internaliza
Publikováno v:
Lipids. 26:1112-1116
Fast atom bombardment mass spectrometry of choline phospholipids produces negative ions characteristic of the intact molecule and tandem mass spectrometry of collision-induced decomposition of M-15 anions characterizes both the identity and substitue
Publikováno v:
The Journal of Immunology. 145:3062-3070
Exposure of human peripheral blood neutrophils to a variety of phagocytic and soluble stimuli is known to induce the synthesis and secretion of platelet-activating factor (PAF), a unique ether-linked phospholipid. It has recently been observed in thi
Publikováno v:
The Journal of Immunology. 145:2602-2607
Platelet-activating factor (PAF) is a highly potent phospholipid mediator known to be active in many biologic systems. To date, little is known of the effect of PAF on B lymphocytes. Using two Ig-secreting B lymphoblastoid cell lines, we have demonst
Publikováno v:
The Journal of clinical psychiatry. 56
The pooled results of 99 subjects from our Veterans Affairs population show that naltrexone-treated subjects had a greater reduction in alcohol craving, number of drinking days, and alcoholic relapse rates when compared with placebo-treated subjects.