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Application of a Convenient Extraction Procedure to Analyze Gamma-Hydroxybutyric Acid in Fatalities Involving Gamma-Hydroxybutyric Acid, Gamma-Butyrolactone, and 1,4-Butanediol

Autor: W C Duer, J V Martin, K L Byers

Publikováno v: Journal of Analytical Toxicology. 25:576-582

The most common chemicals that can be ingested and lead to greater than endogenous levels of gamma-hydroxybutyric acid (GHB) in decedents are salts of GHB, gamma-butyrolactone (GBL), and 1,4-butanediol (BD). Results for three deaths involving the ing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c73dbec2bfc44d08754f52ba6698e5
https://doi.org/10.1093/jat/25.7.576

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Induction of apoptosis in MCF-7:WS8 breast cancer cells by beta-lapachone

Autor: S M, Wuerzberger, J J, Pink, S M, Planchon, K L, Byers, W G, Bornmann, D A, Boothman

Publikováno v: Cancer research. 58(9)

Beta-lapachone (beta-lap) affects a number of enzymes in vitro, including type I topoisomerase (Topo I); however, its exact intracellular target(s) and mechanism of cell killing remain unknown. We compared the cytotoxic responses of MCF-7:WS8 (MCF-7)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7ce8ccbdfda88af50ff874bce0e9f85f
https://pubmed.ncbi.nlm.nih.gov/9581828

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