Výsledky vyhledávání

High-level production of alpha-particle-emitting (211)At and preparation of (211)At-labeled antibodies for clinical use

Autor: M R, Zalutsky, X G, Zhao, K L, Alston, D, Bigner

Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 42(10)

In vitro and in vivo studies in human glioma models suggest that the antitenascin monoclonal antibody 81C6 labeled with the 7.2-h-half-life alpha-particle emitter (211)At might be a valuable endoradiotherapeutic agent for the treatment of brain tumor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8965ad452ae6d1925150c42227b77413
https://pubmed.ncbi.nlm.nih.gov/11585866

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Enhanced binding and inertness to dehalogenation of alpha-melanotropic peptides labeled using N-succinimidyl 3-iodobenzoate

Autor: P K, Garg, K L, Alston, P C, Welsh, M R, Zalutsky

Publikováno v: Bioconjugate chemistry. 7(2)

Two peptides of potential utility for targeting melanoma cells, alpha-melanocyte-stimulating hormone (alpha-MSH) and its more potent analogue [Nle4,D-Phe7]-alpha-MSH, were radioiodinated in 45-65% yield using N-succinimidyl 3-[125I]iodobenzoate (SIB)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cbbc98b34d506f78f72679bbc22dcd61
https://pubmed.ncbi.nlm.nih.gov/8983345

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