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Two-domain MHC class II molecules form stable complexes with myelin basic protein 69-89 peptide that detect and inhibit rat encephalitogenic T cells and treat experimental autoimmune encephalomyelitis

Autor: G G, Burrows, B F, Bebo, K L, Adlard, A A, Vandenbark, H, Offner

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 161(11)

We designed and expressed in bacteria a single-chain two-domain MHC class II molecule capable of binding and forming stable complexes with antigenic peptide. The prototype "beta1alpha1" molecule included the beta1 domain of the rat RT1.B class II mol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b559f04cd4640d309b07d3c8f96a5d6d
https://pubmed.ncbi.nlm.nih.gov/9834080

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