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Human TSLP directly enhances expansion of CD8+ T cells

Autor: Takuji Akamatsu, Junya Tanaka, Tsutomu Chiba, Akiyoshi Nishio, Kazuyuki Saga, K. Kuzushima, Norihiko Watanabe, Masahiro Kido

Publikováno v: Clinical and Experimental Immunology. 154:98-106

SummaryHuman thymic stromal lymphopoietin (TSLP) promotes CD4+ T-cell proliferation both directly and indirectly through dendritic cell (DC) activation. Although human TSLP-activated DCs induce CD8+ T-cell proliferation, it is not clear whether TSLP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5ed48c7d0bb74364fbf41197cff940
https://doi.org/10.1111/j.1365-2249.2008.03731.x

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Identification of a naturally processed HLA-Cw7-binding peptide that cross-reacts with HLA-A24-restricted ovarian cancer-specific CTLs

Autor: E, Yamada, A, Demachi-Okamura, S, Kondo, Y, Akatsuka, S, Suzuki, K, Shibata, F, Kikkawa, K, Kuzushima

Publikováno v: Tissue antigens. 86(3)

Here, we describe an human leukocyte antigen (HLA)-A*24:02-restricted cytotoxic T-lymphocyte (CTL) clone, 1G3, established from naïve CD8(+) T-lymphocytes obtained from a healthy donor stimulated with HLA-modified TOV21G, an ovarian cancer cell line

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::11ff03e72dd57e965ce533dde6eb2b31
https://pubmed.ncbi.nlm.nih.gov/26216489

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The role of self peptides in the allogeneic cross-reactivity of CTLs

Autor: K Kuzushima, R Sun, G M van Bleek, Z Vegh, S G Nathenson

Publikováno v: The Journal of Immunology. 155:594-601

This study presents data relevant to understanding the molecular and structural basis for the cross-reactivity of many CTLs on multiple MHC targets. Five anti-H-2Kb alloreactive CTL clones derived from B6.C-H-2bm1 (bm1), B6.C-H-2bm8 (bm8), and B6.C-H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9e5ed633183749c4ecac57b5e8cf4207
https://doi.org/10.4049/jimmunol.155.2.594

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LAB-IMMUNOLOGY RESEARCH

Autor: M. Fujita, R. Zhang, S. Nakata, K. Kuzushima, D. A. Wainwright, I. V. Balyasnikova, B. Auffinger, A. U. Ahmed, Y. Han, M. S. Lesniak, A. Knight, H. Arnouk, G. Y. Gillespie, W. Britt, Y. Su, M. W. Lowdell, L. S. Lamb, J. Wang, L. Leiss, B. D. Choi, C.-T. Kuan, M. Cai, D. D. Bigner, J. H. Sampson, I. Shibahara, R. Saito, M. Kanamori, Y. Sonoda, T. Kumabe, T. Kikuchi, T. So, N. Ishii, T. Tominaga, L. Zhang, H. Wang, I. Zhang, X. Chen, A. Da Fonseca, H. Fan, B. Badie, E. J. Sayour, P. McLendon, R. Reynolds, R. McLendon, D. A. Mitchell, L. Sanchez-Perez, C. Pham, D. Snyder, W. Xie, X. Cui, M. J. McConnell, K. W. Broadley, K. Farrand, A. Authier, J. H. Brown, M. Hunn, I. Hermans, G. Cantini, F. Pisati, S. Pessina, G. Finocchiaro, S. Pellegatta, J. T. Yeung, R. Hamilton, I. Pollack, R. Jakacki, H. Okada, B. Choi, R. J. Schmittling, C. Flores, L. Johnson, G. A. Archer, B. Raychaudhuri, P. Rayman, P. Huang, J. Ireland, S. Donnola, D. Hamburdzumyan, J. Finke, M. A. Vogelbaum, K. Batich, E. Reap, G. Archer, J. Sampson, D. Mitchell, A. M. Martin, C. Nirschl, M. Polanczyk, K. J. Cohen, D. M. Pardoll, C. G. Drake, M. Lim, W. C. Rutledge, J. Kong, J. Gao, D. A. Gutman, L. A. Cooper, C. Chisolm, L. Scarpace, T. Mikkelsen, J. H. Saltz, C. S. Moreno, D. J. Brat, R. G. Everson, D. N. Lisiero, H. Soto, L. M. Liau, R. M. Prins, G. C. Gonzalez, M. Chae, T. E. Peterson, I. F. Parney, A. J. Johnson

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f8cb2b12b59072c95a98de9da25874
https://europepmc.org/articles/PMC3488777/

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Clinical Manifestations of Primary Herpes Simplex Virus Type 1 Infection in a Closed Community

Autor: K, Kuzushima, H, Kimura, Y, Kino, S, Kido, N, Hanada, M, Shibata, T, Morishima

Publikováno v: Pediatrics. 87:152-158

The clinical features and the molecular epidemiology of primary herpes simplex virus type 1 (HSV-1) infection among children younger than 3 years of age were investigated in day-care nursery. Serial sera were assayed for anti-HSV-1 glycoprotein B ant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560ba1b47c7ce3ba3a6c7e70874fbf98
https://doi.org/10.1542/peds.87.2.152

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Inhibitory effect of herpes simplex virus infection to target cells on recognition of minor histocompatibility antigens by cytotoxic T lymphocytes

Autor: K Kuzushima, K Isobe, T Morishima, A Takatsuki, I Nakashima

Publikováno v: The Journal of Immunology. 144:4536-4540

Target cell lysis by CTL specific for minor histocompatibility Ag (minor HA), which were generated in (C3H/He x BALB/c)F1 mice immunized with A/J mouse spleen cells, was dramatically reduced by infection of HSV to Neuro-2a (A/J mouse origin) cells as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d4f9cc2c13086b6e97dca8d1b13c68a5
https://doi.org/10.4049/jimmunol.144.12.4536

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