Zobrazeno 1 - 10
of 703
pro vyhledávání: '"K Karjalainen"'
Autor:
Anna K. Hartikainen, Imran Khan, Essi K. Karjalainen, Laura Renkonen-Sinisalo, Perttu Arkkila, Jonna Jalanka, Anna H. Lepistö, Reetta Satokari
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTAltered microbiota and impaired host immune function have been linked to the pathogenesis of pouchitis. We used 16S rRNA gene sequencing and RNA sequencing data from a previous randomized clinical trial (RCT) on fecal microbiota transplantati
Externí odkaz:
https://doaj.org/article/784ec60ba06f4b3d82901b543ba4588a
Autor:
Anu Pasanen, Minna K Karjalainen, FinnGen, Ge Zhang, Heli Tiensuu, Antti M Haapalainen, Marja Ojaniemi, Bjarke Feenstra, Bo Jacobsson, Aarno Palotie, Hannele Laivuori, Louis J Muglia, Mika Rämet, Mikko Hallman
Publikováno v:
PLoS Genetics, Vol 19, Iss 10, p e1010982 (2023)
BackgroundPreterm birth (MethodsWe conducted a genome-wide meta-analysis of gestational duration and spontaneous preterm birth in 68,732 and 98,370 European mothers, respectively.ResultsThe meta-analysis detected 15 loci associated with gestational d
Externí odkaz:
https://doaj.org/article/f14300073a8b497a870ffbbe353c0e10
Autor:
Pia Holma, Paula Pesonen, Minna K. Karjalainen, Marjo-Riitta Järvelin, Sara Väyrynen, Eeva Sliz, Anni Heikkilä, Mikko R.J. Seppänen, Johannes Kettunen, Juha Auvinen, Timo Hautala
Publikováno v:
EBioMedicine, Vol 94, Iss , Pp 104712- (2023)
Summary: Background: We investigated health consequences and genetic properties associated with serum IgG concentration in a young and working age general population. Methods: Northern Finland Birth Cohort 1966 (NFBC1966, n = 12,231) health data have
Externí odkaz:
https://doaj.org/article/723d120d3d994388abdc6dbfa7aee27e
Publikováno v:
Gynecology and Obstetrics Clinical Medicine, Vol 2, Iss 2, Pp 57-62 (2022)
Aims: To evaluate the medium term efficacy and safety of Altis and Solyx single incision slings (SIS) compared with tension-free vaginal tape (TVT) Abbrevo trans-obturator sling. We hypothesize that both SIS show little difference in efficacy and saf
Externí odkaz:
https://doaj.org/article/6ca09baa31e84c87856b49988e76c3fb
Autor:
Lauri I. Lavikainen, Gordon H. Guyatt, Yung Lee, Rachel J. Couban, Anna L. Luomaranta, Ville J. Sallinen, Ilkka E. J. Kalliala, Paul J. Karanicolas, Rufus Cartwright, Riikka L. Aaltonen, Kaisa Ahopelto, Karoliina M. Aro, Ines Beilmann-Lehtonen, Marco H. Blanker, Jovita L. Cárdenas, Samantha Craigie, Päivi J. Galambosi, Herney A. Garcia-Perdomo, Fang Zhou Ge, Huda A. Gomaa, Linglong Huang, Matthew L. Izett-Kay, Kirsi M. Joronen, Päivi K. Karjalainen, Nadina Khamani, Tuomas P. Kilpeläinen, Antti J. Kivelä, Tapio Korhonen, Hanna Lampela, Anne K. Mattila, Borna Tadayon Najafabadi, Taina P. Nykänen, Carolina Nystén, Sanna M. Oksjoki, Sanjay Pandanaboyana, Negar Pourjamal, Chathura B. B. Ratnayake, Aleksi R. Raudasoja, Tino Singh, Riikka M. Tähtinen, Robin W. M. Vernooij, Yuting Wang, Yingqi Xiao, Liang Yao, Jari Haukka, Kari A. O. Tikkinen
Publikováno v:
Systematic Reviews, Vol 10, Iss 1, Pp 1-13 (2021)
Abstract Background Venous thromboembolism (VTE) and bleeding are serious and potentially fatal complications of surgical procedures. Pharmacological thromboprophylaxis decreases the risk of VTE but increases the risk of major post-operative bleeding
Externí odkaz:
https://doaj.org/article/976c1cced05c4ff886a2e31a73428251
Autor:
Johanna M. Huusko, Heli Tiensuu, Antti M. Haapalainen, Anu Pasanen, Pinja Tissarinen, Minna K. Karjalainen, Ge Zhang, Kaare Christensen, Kelli K. Ryckman, Bo Jacobsson, Jeffrey C. Murray, Stephen F. Kingsmore, Mikko Hallman, Louis J. Muglia, Mika Rämet
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Heat shock proteins are involved in the response to stress including activation of the immune response. Elevated circulating heat shock proteins are associated with spontaneous preterm birth (SPTB). Intracellular heat shock proteins act as m
Externí odkaz:
https://doaj.org/article/f305df8cd6b34e51b15c496289d931fa
Autor:
Pauliina Salmi, Kalle Ryymin, Anna K. Karjalainen, Anna Mikola, Emilia Uurasjärvi, Julia Talvitie
Publikováno v:
Water Science and Technology, Vol 84, Iss 1, Pp 89-100 (2021)
Microplastics (MPs) from households, stormwater, and various industries are transported to wastewater treatment plants (WWTPs), where a high proportion of them are captured before discharging their residuals to watersheds. Although recent studies hav
Externí odkaz:
https://doaj.org/article/9afc0930602c438fab574a7bcee9a257
Sulfate toxicity to early life stages of European whitefish (Coregonus lavaretus) in soft freshwater
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 208, Iss , Pp 111763- (2021)
Sulfate occurs naturally in the aquatic environment but its elevated levels can be toxic to aquatic life in freshwater environments. We investigated the toxicity of sulfate in humic, soft freshwater to whitefish (Coregonus lavaretus) from fertilizati
Externí odkaz:
https://doaj.org/article/52519bcfd83d49f6851789c1b949b386
Autor:
Stephanie K. Bopp, Robert Barouki, Werner Brack, Silvia Dalla Costa, Jean-Lou C.M. Dorne, Paula E. Drakvik, Michael Faust, Tuomo K. Karjalainen, Stylianos Kephalopoulos, Jacob van Klaveren, Marike Kolossa-Gehring, Andreas Kortenkamp, Erik Lebret, Teresa Lettieri, Sofie Nørager, Joëlle Rüegg, Jose V. Tarazona, Xenia Trier, Bob van de Water, Jos van Gils, Åke Bergman
Publikováno v:
Environment International, Vol 120, Iss , Pp 544-562 (2018)
Humans and wildlife are exposed to an intractably large number of different combinations of chemicals via food, water, air, consumer products, and other media and sources. This raises concerns about their impact on public and environmental health. Th
Externí odkaz:
https://doaj.org/article/ff1d544fb7bc4bf59231031eba3825ef
Autor:
Heli Tiensuu, Antti M Haapalainen, Minna K Karjalainen, Anu Pasanen, Johanna M Huusko, Riitta Marttila, Marja Ojaniemi, Louis J Muglia, Mikko Hallman, Mika Rämet
Publikováno v:
PLoS Genetics, Vol 15, Iss 6, p e1008107 (2019)
Spontaneous preterm birth (SPTB) is the leading cause of neonatal death and morbidity worldwide. Both maternal and fetal genetic factors likely contribute to SPTB. We performed a genome-wide association study (GWAS) on a population of Finnish origin
Externí odkaz:
https://doaj.org/article/40722b32dea848e9ab80e286121da752