Zobrazeno 1 - 10
of 336
pro vyhledávání: '"K Kaarela"'
Autor:
Daniel E. Weeks, V. Goedecke, Jonathan Wilson, A. M. Crane, Matthew A. Brown, E. Jaakkola, Jaakko Tuomilehto, W. Kaluza, Markku J Kauppi, Kari Laiho, B P Wordsworth, K. Kaarela
Genetic polymorphisms of the IL10 promoter region have been implicated in many autoimmune diseases, including seronegative spondyloarthropathies. We studied three SNPs (IL10-1087, -824, and -597) and two microsatellites (IL10R and IL10G) lying within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27be2a2e8854f52d88f9d0332c132ae
https://doi.org/10.1038/sj.gene.6363930
https://doi.org/10.1038/sj.gene.6363930
Autor:
Am-M. Sims, I. Herzberg, Matthew A. Brown, B P Wordsworth, Markku J Kauppi, J. Tuomilehto, E. Jaakkola, K. Kaarela, K. Laiho, Sinead Brophy, Andrei Calin, A. M. Crane, Linda A. Bradbury
Objectives. To determine whether genetic polymorphisms in or near the transforming growth factor beta1 (TGFB1) locus were associated with susceptibility to or severity of ankylosing spondylitis (AS). Methods. Five intragenic single-nucleotide polymor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c2bf30400305e0f5c15ff946feaf4e
https://ora.ox.ac.uk/objects/uuid:335ef2ec-2e20-418c-8d30-d0557b9941d9
https://ora.ox.ac.uk/objects/uuid:335ef2ec-2e20-418c-8d30-d0557b9941d9
Autor:
Harri Hämäläinen, Heikki Kröger, Markku Kauppi, K Kaarela, Markku Hakala, A Kotaniemi, Salme Järvenpää
Publikováno v:
Joint Bone Spine. 74:482-487
Objective: To ascertain changes in axial bone mineral in premenopausal women with severe rheumatoid arthritis (RA) treated with and without prednisolone (PRED), we conducted a two-year follow-up study of axial bone mineral density (BMD) and bone mine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b671ad9754fb43643880ec8fb4a62a9
https://doi.org/10.1016/j.jbspin.2007.01.021
https://doi.org/10.1016/j.jbspin.2007.01.021
Publikováno v:
Journal of Internal Medicine. 262:466-469
Maury CPJ, Aittoniemi J, Tiitinen S, Laiho K, Kaarela K, Hurme M. (University of Helsinki, Helsinki; Centre for Laboratory Medicine, Pirkanmaa Hospital District, Tampere; Rheumatism Foundation Hospital, Heinola and University of Tampere, Tampere; and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3230a7290f0489a211f35a332a5da65e
https://doi.org/10.1111/j.1365-2796.2007.01838.x
https://doi.org/10.1111/j.1365-2796.2007.01838.x
Autor:
I. Herzberg, M. Barnardo, J J Pointon, Matthew A. Brown, Jaakko Tuomilehto, E. Jaakkola, B P Wordsworth, K. Kaarela, Markku J Kauppi, Kari Laiho, E. Tuomilehto-Wolf
Publikováno v:
Annals of the Rheumatic Diseases. 65:775-780
Objective: To determine the influence of HLA-B27 homozygosity and HLA-DRB1 alleles in the susceptibility to, and severity of, ankylosing spondylitis in a Finnish population. Methods: 673 individuals from 261 families with ankylosing spondylitis were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f520f1dcfaf56a76d709cad430955cf
https://doi.org/10.1136/ard.2005.041103
https://doi.org/10.1136/ard.2005.041103
Publikováno v:
Journal of Internal Medicine. 256:145-152
OBJECTIVE In amyloid A (AA) amyloidosis the receptor for advanced glycation end products is a target for the circulating amyloid precursor protein (SAA) resulting in upregulation of the proinflammatory cytokine pathway. Besides inducing hepatic SAA s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93d289427e3be828b9b120d62e957dbf
https://doi.org/10.1111/j.1365-2796.2004.01353.x
https://doi.org/10.1111/j.1365-2796.2004.01353.x
Publikováno v:
Arthritis & Rheumatism. 48:3068-3076
Objective To study tumor necrosis factor alpha (TNFalpha) -308 gene promoter polymorphism and circulating levels of TNFalpha and soluble TNF receptor type I (sTNFRI) in rheumatoid arthritis (RA) patients with and without reactive amyloidosis. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d9f381f616d515f144971a1b6ee565
https://doi.org/10.1002/art.11294
https://doi.org/10.1002/art.11294
Publikováno v:
Amyloid. 9:141-144
Objective. to study the circulating levels of interleukin-18 (IL-18), a proinflammatory cytokine implicated in the T helper 1 response, inpatients with rheumatoid arthrtitis (RA) with or without amyloidosis.Methods. Plasma IL-18 levels were studied b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35b243ac05cdbea5d964e7e07cfe5d3e
https://doi.org/10.3109/13506120208995247
https://doi.org/10.3109/13506120208995247
Publikováno v:
Amyloid. 8:270-273
The role of apolipoprotein (apo) E in the pathogenesis of reactive amyloidosis is unclear. Here we evaluated the apoE phenotype distribution and apolipoprotein e allele frequencies in 55 adult patients with seropositive, erosive RA with amyloid and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8860dec342225e24c58ed9136f5f6a8f
https://doi.org/10.3109/13506120108993824
https://doi.org/10.3109/13506120108993824
Publikováno v:
Rheumatology. 39:288-292
Objective. To evaluate radiographically the glenohumeral (GH ) joint space in patients with long-term rheumatoid arthritis (RA). Methods. A cohort of 74 patients with RA were followed prospectively for 15 yr. At the end point, 148 shoulders were radi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ded7c34bacff00eb435fd4fadb20e9e
https://doi.org/10.1093/rheumatology/39.3.288
https://doi.org/10.1093/rheumatology/39.3.288