Zobrazeno 1 - 10 of 46 pro vyhledávání: '"K K Eklund"'
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Akademický článek
The biological activity of serum bacterial lipopolysaccharides associates with disease activity and likelihood of achieving remission in patients with rheumatoid arthritis
Autor: J. Parantainen, G. Barreto, R. Koivuniemi, H. Kautiainen, D. Nordström, E. Moilanen, M. Hämäläinen, M. Leirisalo-Repo, K. Nurmi, K. K. Eklund
Publikováno v: Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-10 (2022)
Abstract Background Dysbiotic intestinal and oral microbiota have been implicated in the pathogenesis of rheumatoid arthritis (RA), but the mechanisms how microbiota could impact disease activity have remained elusive. The aim of this study was to as
Externí odkaz: https://doaj.org/article/816e8f97ea8b4e0084d5f79d763f2d51
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2
Glucocorticoids inhibit the cytokine-induced proliferation of mast cells, the high affinity IgE receptor-mediated expression of TNF-alpha, and the IL-10-induced expression of chymases
Autor: K K Eklund, D E Humphries, Z Xia, N Ghildyal, D S Friend, V Gross, R L Stevens
Publikováno v: The Journal of Immunology. 158:4373-4380
Mast cells are a heterogeneous family of immune cells that, when activated through their high affinity IgE receptors (Fc epsilonRI), release various granule mediators (e.g., neutral proteases and serglycin proteoglycans) and proinflammatory cytokines
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f5d0389f29cd0895fd0a24a08be4027
https://doi.org/10.4049/jimmunol.158.9.4373
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3
Imatinib mesylate alleviates diarrhea in a mouse model of intestinal allergy
Autor: K, Vaali, J, Lappalainen, A H, Lin, M I, Mäyränpää, P T, Kovanen, A, Berstad, K K, Eklund
Publikováno v: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 24(7)
When sensitized epicutaneously and challenged orally with ovalbumin, Balb/c mice develop allergen-induced diarrhea. As mast cells play important roles in diarrhea, we studied whether allergic diarrhea could be alleviated with imatinib mesylate.Balb/c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::140a4fbc14b41fb23df2b8f2a70a9c16
https://pubmed.ncbi.nlm.nih.gov/22709239
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4
Induction by IL-9 and suppression by IL-3 and IL-4 of the levels of chromosome 14-derived transcripts that encode late-expressed mouse mast cell proteases
Autor: K K Eklund, N Ghildyal, K F Austen, R L Stevens
Publikováno v: The Journal of Immunology. 151:4266-4273
Immature, rIL-3-dependent mouse bone marrow-derived mast cells (BMMC) contain high steady-state levels of the mouse mast cell protease (mMCP) 5 transcript but undetectable levels of the mMCP-1, mMCP-2, or mMCP-4 transcripts even though all four of th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a438f27ffb702a8dc46762db8fc868cd
https://doi.org/10.4049/jimmunol.151.8.4266
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6
Interleukin-1 and collagenases around loosening total hip prostheses
Autor: Y T, Konttinen, H, Kurvinen, M, Takagi, J E, Michelsson, K K, Eklund, L, Nordsletten, L, Buø, A O, Aasen, S, Santavirta
Publikováno v: Clinical and experimental rheumatology. 14(3)
The present study was carried out to assess the expression of IL-1 in periprosthetic tissue and to relate it to local collagenase levels.Interface tissue between the implant and bone was obtained from hip revision operations and was compared to healt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aec2bde15ac704b3ad5008b3fe4c6b86
https://pubmed.ncbi.nlm.nih.gov/8809439
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7
Mast cells in loosening of totally replaced hips
Autor: S A, Solovieva, A, Ceponis, Y T, Konttinen, M, Takagi, A, Suda, K K, Eklund, T, Sorsa, S, Santavirta
Publikováno v: Clinical orthopaedics and related research. (322)
This study evaluated mast cells in tissue around loose total hip implants. Interface and pseudocapsular tissues were obtained from 6 patients with a loose hip prosthesis. Mast cells were labeled with monoclonal mouse antihuman antibodies against tryp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4b32a0a64f87bbe0034f0012a3322aa9
https://pubmed.ncbi.nlm.nih.gov/8542692
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8
Eosinophilic fasciitis, myositis and arthritis as early manifestations of peripheral T‐cell lymphoma
Autor: K K Eklund, P Anttila, Marjatta Leirisalo-Repo
Publikováno v: Scandinavian Journal of Rheumatology. 32:376-377
(2003). Eosinophilic fasciitis, myositis and arthritis as early manifestations of peripheral T‐cell lymphoma. Scandinavian Journal of Rheumatology: Vol. 32, No. 6, pp. 376-377.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4bda6bb70dfe6b1fb4656ef630d1c3fe
https://doi.org/10.1080/03009740410005061
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9
Mouse bone marrow-derived mast cells (mBMMC) obtained in vitro from mice that are mast cell-deficient in vivo express the same panel of granule proteases as mBMMC and serosal mast cells from their normal littermates
Autor: N Ghildyal, K F Austen, Richard L. Stevens, Daniel S. Friend, K K Eklund, V. Schiller
Publikováno v: The Journal of Experimental Medicine
The ear, skin, and purified serosal mast cells of WBB6F1/J-(+/+) (WB-(+/+)) and WCB6F1/J-(+/+) (WC-(+/+)) mice contain high steady-state levels of the transcripts that encode mouse mast cell protease (mMCP) 2, mMCP-4, mMCP-5, mMCP-6, and mouse mast c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7868eef30b313d40fbe71f2d8a7d28c0
https://pubmed.ncbi.nlm.nih.gov/8006601
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