Zobrazeno 1 - 10
of 23
pro vyhledávání: '"K K Colburn"'
Publikováno v:
Lupus. 10:410-417
Systemic lupus erythematosus (SLE) is characterized by autoantibodies, including antibodies to the nucleosides of DNA. Guanosine is the most immunogenic nucleoside. In this study serum antiguanosine antibody levels were compared with disease activity
Publikováno v:
JCR: Journal of Clinical Rheumatology. 5:201-205
Disease activity in rheumatoid arthritis (RA) is difficult to measure objectively. Both clinical and laboratory measures were evaluated by the statistical method of consensus analysis. In the literature, laboratory tests as a group have proved more e
Publikováno v:
Annals of the Rheumatic Diseases. 49:910-915
To measure rheumatoid factors specific for patients with rheumatoid arthritis an enzyme linked immunosorbent assay (ELISA) was developed to measure rheumatoid factors in human serum that bind a cross-reactive determinant shared on human and other mam
Publikováno v:
The Journal of Immunology. 144:2653-2658
In order to identify unique structural features of pathogenic autoantibodies to DNA in SLE, a murine anti-anti-DNA (anti-Id) mAb (mAb 1C7) was produced in response to immunization of lupus mice with a syngeneic anti-DNA mAb (mAb 3E10). Immunization o
Publikováno v:
Journal of Investigative Medicine. 55:S121
We report the case of a 39-year-old African-American lady diagnosed with a cutaneous vasculitis manifesting as hyperpigmented areas over the lower extremities. She was ANA and ds-DNA positive and was started on immunosuppressive agents, which were di
Autor:
L. M. Green, L. S. Ortloff, B. M. Bianski, M. B. Taylor, K. K. Colburn, B. T. Andersen, D. V. Cooray
Publikováno v:
Journal of Investigative Medicine. 54:S132.3-S132
Purpose The expression of CD40 ligand (CD40L) in individuals with systemic lupus erythematosus (SLE) is prolonged when compared to expression on normal T cells. A defect in the down-regulation of the Ras, an intracellular G-protein involved in cell p
Publikováno v:
Journal of Investigative Medicine. 53:S361.2-S361
A host of immunologic abnormalities have been thoroughly described in systemic lupus erythematosus. There is an increasing body of evidence that the production of autoantibodies is the result of abnormal regulation of T cells of the early monitored r
Autor:
S. Enloe-Whitaker, K. K. Colburn
Publikováno v:
Journal of Investigative Medicine. 53:S130.4-S130
Background and Objective Kaposi9s sarcoma (KS) is a low-grade vascular tumor associated with infection with human herpesvirus 8 (HHV-8). KS, the most common tumor among HIV positive patients also afflicts organ transplant patients. Prior to the AIDS
Publikováno v:
The Journal of Immunology. 139:2925-2928
A cloned lymphoblast cell line, hRF-1, that secreted human monoclonal IgG4 rheumatoid factor autoantibody was produced by Epstein-Barr virus transformation of lymphocytes from rheumatoid arthritis synovium. The binding of hRF-1 rheumatoid factor to I
Publikováno v:
Infection and Immunity. 30:674-677
Staphylococcal protein A is a bacterial cell wall product that binds human immunoglobulin G and thereby interferes with opsonization and phagocytosis of Staphylococcus aureus by neutrophils. Phagocytic cells are also responsive to various non-immunog