Zobrazeno 1 - 10
of 51
pro vyhledávání: '"K K, McMahon"'
Autor:
K K McMahon, K J Piron
Publikováno v:
Biochemical Journal. 270:591-597
The subcellular distributions of endogenous ADP-ribosylation products in hearts from 1-day-old neonatal and adult rats were investigated. In adult rat heart a 52 kDa mono-ADP-ribosylation product was identified in the plasma membrane fraction. In con
Publikováno v:
Advances in experimental medicine and biology. 419
Earlier we demonstrated that meta-iodobenzylguanidine (MIBG), a specific inhibitor of arginine mono-ADP-ribosylation blocks proliferation and differentiation of chick skeletal myogenic cells in culture (Exp. Cell Res., 1992, 201:33-42). Membrane frac
Publikováno v:
The American journal of physiology. 269(3 Pt 2)
The objective of this study was to determine if levels and function of Gs alpha and G alpha i-2 in rat hearts change over time following acute myocardial infarction (MI), and if so, whether the changes in G proteins are associated with changes in hea
Publikováno v:
Biochemical Journal. 212:499-506
Incorporation of [32P]Pi into phosphatidic acid and phosphatidylinositol of hamster epididymal adipocytes was partially inhibited by 3-isobutyl-1-methylxanthine. This effect of 3-isobutyl-1-methylxanthine was antagonized by isopropyl-N6-phenyladenosi
Autor:
K K, McMahon, R J, Schimmel
Publikováno v:
Journal of cyclic nucleotide research. 8(1)
The diterpene forskolin has been shown by Seamon et al (Proc. Natl. Acad. Sci., USA, 78: 3363-3367, 1981) to elicit a large increase in adenylate cyclase activity and to permit further activation by GTP, GDP, sodium fluoride and hormones. The present
Autor:
K K, McMahon, R J, Schimmel
Publikováno v:
Molecular pharmacology. 20(2)
Autor:
K K, McMahon, M M, Hosey
Publikováno v:
Molecular pharmacology. 28(5)
Analysis of [3H]quinuclidinyl benzilate/acetylcholine competition curves indicated that the agonist acetylcholine bound with three different affinities to chick heart muscarinic receptors. The estimated KD values for acetylcholine were 2.7, 240, and
Publikováno v:
Journal of cyclic nucleotide and protein phosphorylation research. 9(4-5)
The present communication describes the actions of 9-beta-D-arabino-furanosylguanine-5'-triphosphate (AraGTP) on hamster white and brown adipocyte and chick cardiac adenylate cyclase. AraGTP supports isoproterenol stimulation of adenylate cyclase in
Autor:
T, Scott, K K, McMahon
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 247(1)
The muscarinic receptor in the rat large airway was characterized by radioligand binding experiments. Using I-quinuclidinyl (phenyl-4-[3H])benzilate ([3H]QNB) as the radioligand, the receptor appears to be homogenous. The receptor density was 23 fmol
Autor:
K K, McMahon
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 251(1)
The pertussis toxin-sensitive G proteins (guanine nucleotide binding proteins)-muscarinic receptor interactions in 18-day fetal to adult rat hearts were studied. The collective concentration of these G proteins was measured by pertussis toxin-depende