Zobrazeno 1 - 5
of 5
pro vyhledávání: '"K K, Manouilov"'
Autor:
Chung K. Chu, F. D. Boudinot, Z.-S. Xu, K. K. Manouilov, L. S. Manouilova, Raymond F. Schinazi
Publikováno v:
Antiviral Chemistry and Chemotherapy. 8:409-415
The lymphatic system is a primary target for early anti-human immunodeficiency virus drug therapy. Strategies are currently being sought to enhance the delivery of nucleoside analogues such as 3′-deoxy-2′,3′-didehydrothymidine (stavudine; d4T)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de04ccf5c211060b6295f5ca5919ee4a
https://doi.org/10.1177/095632029700800503
https://doi.org/10.1177/095632029700800503
Autor:
Harold M. McClure, Raymond F. Schinazi, K. K. Manouilov, F. D. Boudinot, Huizhong Chen, Chung K. Chu
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 691:425-432
(−)-β- d -2-Aminopurine dioxolane (APD), (−)-β- d -2-amino-6-chloropurine dioxolane (ACPD) and dioxolane guanine (DXG) are nucleoside analogues possessing potent activity against human immunodeficiency virus (HIV) and hepatitis B virus (HBV) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250dfdaee4d7d6e75df221779be9f114
https://doi.org/10.1016/s0378-4347(96)00473-2
https://doi.org/10.1016/s0378-4347(96)00473-2
Autor:
I. I. Fedorov, K. K. Manouilov, Chung Hong, C. A. White, Raymond F. Schinazi, Lakshmi P. Kotra, Chung K. Chu, F. D. Boudinot
Publikováno v:
Antiviral Chemistry and Chemotherapy. 6:230-238
Human immunodeficiency virus appears to be proliferating within the lymphatic system throughout the period of clinical latency. Targeting of anti-HIV compounds to the lymphatic tissue may therefore provide therapeutic benefits. The purpose of this in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b0288ff28a2bc1083d2f96ce088030d
https://doi.org/10.1177/095632029500600405
https://doi.org/10.1177/095632029500600405
Publikováno v:
Antiviral research. 35(3)
9-( β - d -1,3-Dioxolan-4-yl)guanine (DXG) exhibits potent antiviral activity against human immunodeficiency virus type 1 (HIV-1) and hepatitis B virus (HBV) in vitro. However, since DXG possesses limited aqueous solubility, a more water soluble pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c8a350249b7a9d52c7a6db9714579c
https://pubmed.ncbi.nlm.nih.gov/9298758
https://pubmed.ncbi.nlm.nih.gov/9298758
Autor:
T, Koudriakova, K K, Manouilov, K, Shanmuganathan, L P, Kotra, F D, Boudinot, E, Cretton-Scott, J P, Sommadossi, R F, Schinazi, C K, Chu
Publikováno v:
Journal of medicinal chemistry. 39(23)
In an effort to improve the pharmacokinetic properties and tissue distribution of 2'-F-ara-ddI, two lipophilic prodrugs, 6-azido-2'-3'-dideoxy-2'-fluoro-beta-D- arabinofuranosylpurine (FAAddP, 4) and N6-methyl-2'-3'-dideoxy-2'-fluoro-beta-D-arabinofu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b87f16c100f3eaa6639804cc7bda0b5
https://pubmed.ncbi.nlm.nih.gov/8917656
https://pubmed.ncbi.nlm.nih.gov/8917656