Zobrazeno 1 - 10 of 140 pro vyhledávání: '"K J Taylor"'
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Abstract P3-06-03: Downregulation of histone H2A and H2B pathways is associated with anthracycline sensitivity in breast cancer
Autor: Richard Marcellus, Nicola Lyttle, Melanie Spears, K. J. Taylor, Paul M. Krzyzanowski, Paul C. Boutros, Nazleen Lobo, CQ Yao, Irina Kalatskaya, Lincoln Stein, Jms Bartlett, Linda Liao, Chris Twelves, M Braunstein
Publikováno v: Cancer Research. 76:P3-06
Background: Meta-analyses performed by the Early Breast Cancer Trialists Collaborative Group demonstrated a significant increase in disease free and overall survival through the addition of anthracyclines to polychemotherapy. Anthracyclines have, how
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8924e3b016b98aaadd799322d5ceefbf
https://doi.org/10.1158/1538-7445.sabcs15-p3-06-03
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3
Galactorrhoea of the neck following pectoralis major reconstruction of a pharyngeal defect
Autor: K J Taylor, Gac Wheble, M Potter
We describe a case of postoperative galactorrhea following the use of a pedicled pectoralis major myocutaneous flap for reconstruction of a pharyngolaryngeal defect in a woman with squamous cell carcinoma. We believe this to be unique in the literatu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbcbe7c3244ace47ea3262609ad2f7c4
https://europepmc.org/articles/PMC5392810/
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4
Abstract P5-03-11: Sensitivity to cell cycle inhibitors in taxane resistant breast cancer models
Autor: Nicola Lyttle, Melanie Spears, Linda Liao, Charlie Gourley, K. J. Taylor, David Cameron, Jms Bartlett
Publikováno v: Cancer Research. 79:P5-03
Background: The use of anthracycline and taxane chemotherapy has improved overall and disease-free survival in breast cancer. However these agents have significant toxicity. In addition, breast cancers can acquire or possess intrinsic chemoresistance
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3fd92dd784d611ffb4ede79d8556dd20
https://doi.org/10.1158/1538-7445.sabcs18-p5-03-11
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5
Abstract P5-08-14: Deregulated histone and cell cycle pathways are associated with anthracycline resistance in breast cancer
Autor: Melanie Spears, Rima Al-awar, Jms Bartlett, Paul M. Krzyzanowski, Linda Liao, Nicola Lyttle, M Braunstein, Richard Marcellus, K. J. Taylor, Irina Kalatskaya, Lincoln Stein
Publikováno v: Cancer Research. 73:P5-08
Drug resistance in breast cancer is the major obstacle to a successful outcome following chemotherapy treatment. While a well-recognized mechanism of resistance involves upregulation of multidrug resistance (MDR) genes, the complexity and hierarchy o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::479033914472e2bb9735380cc0859963
https://doi.org/10.1158/0008-5472.sabcs13-p5-08-14
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6
Downregulation of histone H2A and H2B pathways is associated with anthracycline sensitivity in breast cancer
Autor: Cindy Q. Yao, Irina Kalatskaya, Nicola Lyttle, Paul M. Krzyzanowski, Melanie Spears, Paul C. Boutros, Marsela Braunstein, Chris Twelves, Lincoln Stein, Richard Marcellus, John M. S. Bartlett, Linda Liao, K. J. Taylor, Nazleen Lobo
Publikováno v: Breast cancer research : BCR, vol 18, iss 1
Braunstein, M, Liao, L, Lyttle, N, Lobo, N, Taylor, K J, Krzyzanowski, P M, Kalatskaya, I, Yao, C Q, Stein, L D, Boutros, P C, Twelves, C J, Marcellus, R, Bartlett, J M S & Spears, M 2016, ' Downregulation of histone H2A and H2B pathways is associated with anthracycline sensitivity in breast cancer ', Breast Cancer Research, vol. 18, no. 1, 16 . https://doi.org/10.1186/s13058-016-0676-6
Breast Cancer Research : BCR
Background Drug resistance in breast cancer is the major obstacle to effective treatment with chemotherapy. While upregulation of multidrug resistance genes is an important component of drug resistance mechanisms in vitro, their clinical relevance re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e76f3478b7d23bb2ffd685bf72f8d0
https://escholarship.org/uc/item/4cf3v6v1
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7
Think of your art-eries: Arts participation, behavioural cardiovascular risk factors and mental well-being in deprived communities in London
Autor: Adrian Renton, Ge Yu, Mark Petticrew, Norma Daykin, K. J. Taylor, Gemma Phillips
Publikováno v: Public Health
Summary Objectives To investigate the association of participation in arts and cultural activities with health behaviours and mental well-being in low-income populations in London. Study design Cross-sectional, community-based observational study. Me
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08072ebd023d9de3241d4473a7d66031
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8
Conformational Preferences of Linear β-Defensins Are Revealed by Ion Mobility-Mass Spectrometry
Autor: Dominic J. Campopiano, Bryan J. McCullough, Martin De Cecco, Julia R. Dorin, K. J. Taylor, Emily S. Seo, Perdita E. Barran, Derek Macmillan, David Clarke
Publikováno v: The Journal of Physical Chemistry B. 114:2312-2318
In recent times there has been an enormous rise in resistance to synthetic antibiotics as well as an increase in the virulence of bacteria, the so-called "superbugs". This problem has catalyzed a search for novel molecules to fight bacteria, which in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cacba3252f1381793df54e9575ba17a9
https://doi.org/10.1021/jp9111662
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9
Defensin-related peptide 1 (Defr1) is allelic to Defb8 and chemoattracts immature DC and CD4+ T cells independently of CCR6
Autor: Dominic J. Campopiano, Sarah E. M. Howie, Kay Samuel, K. J. Taylor, Perdita E. Barran, Joost J. Oppenheim, Uday Pathania, Natalie L. Reynolds, Mark Rolfe, Dave J Clarke, Derek Macmillan, Julia R. Dorin, Fiona Kilanowski, De Yang
Publikováno v: Taylor, K, Rolfe, M, Reynolds, N, Kilanowski, F, Pathania, U, Clarke, D, Yang, D, Oppenheim, J, Samuel, K, Howie, S, Barran, P, Macmillan, D, Campopian, D & Dorin, J 2009, ' Defensin-related peptide 1 (Defr1) is allelic to Defb8 and chemoattracts immature DC and CD4(+) T cells independently of CCR6 ', European Journal of Immunology, vol. 39, no. 5, pp. 1353-1360 . https://doi.org/10.1002/eji.200838566
European Journal of Immunology
beta-Defensins comprise a family of cationic, antimicrobial and chemoattractant peptides. The six cysteine canonical motif is retained throughout evolution and the disulphide connectivities stabilise the conserved monomer structure. A murine beta-def
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e63cefa3ebeafce8f085678790ca1f4a
https://doi.org/10.1002/eji.200838566
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10
Development of an Ion Mobility Quadrupole Time of Flight Mass Spectrometer
Autor: Bryan J. McCullough, K. J. Taylor, Perdita E. Barran, Julia R. Dorin, Paul Kemper, Derek Macmillan, Jason M. D. Kalapothakis, Hayden Eastwood
Publikováno v: Analytical Chemistry. 80:6336-6344
We describe here a new ion mobility capable mass spectrometer which comprises a drift cell for mobility separation and a quadrapole time of flight mass spectrometer for mass analysis--the MoQTOF. A commercial QToF instrument (Micromass UK Ltd., Manch
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb0e304842f8b45f7bd0a52783e779d
https://doi.org/10.1021/ac800651b
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