Zobrazeno 1 - 10
of 155
pro vyhledávání: '"K J Kwon-Chung"'
Autor:
M. J. Davis, R. E. Martin, G. M. Pinheiro, E. S. Hoke, S. Moyer, K. Ueno, J. L. Rodriguez-Gil, M. A. Mallett, J. S. Khillan, W. J. Pavan, Y. C. Chang, K. J. Kwon-Chung
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Cryptococcosis remains a significant threat to human health. While the popular C57BL/6J mouse model of cryptococcosis has some advantages, there are some serious shortcomings that limit the ability of researchers to address the disease. Sinc
Externí odkaz:
https://doaj.org/article/1e8e033c4a354621aab6186093ecdc90
Autor:
Tomoki Yoshida, Yun C. Chang, Yutaka Ebizuka, Hiroshi Tomoda, Huei-Fung Tsai, K. J. Kwon-Chung, Natsuki Nambu, Isao Fujii, Nobutada Tanaka
Publikováno v:
Environ Microbiol Rep
Conidial pigment is an important virulence factor in Aspergillus fumigatus, a human fungal pathogen. The biosynthetic gene cluster for 1,8-dihydroxynaphthalene (DHN)-melanin in A. fumigatus consists of six genes, alb1, ayg1, arp1, arp2, abr1, and abr
Autor:
C. A. D’Souza, J. W. Kronstad, G. Taylor, R. Warren, M. Yuen, G. Hu, W. H. Jung, A. Sham, S. E. Kidd, K. Tangen, N. Lee, T. Zeilmaker, J. Sawkins, G. McVicker, S. Shah, S. Gnerre, A. Griggs, Q. Zeng, K. Bartlett, W. Li, X. Wang, J. Heitman, J. E. Stajich, J. A. Fraser, W. Meyer, D. Carter, J. Schein, M. Krzywinski, K. J. Kwon-Chung, A. Varma, J. Wang, R. Brunham, M. Fyfe, B. F. F. Ouellette, A. Siddiqui, M. Marra, S. Jones, R. Holt, B. W. Birren, J. E. Galagan, C. A. Cuomo
Publikováno v:
mBio, Vol 2, Iss 1 (2011)
ABSTRACT Cryptococcus gattii recently emerged as the causative agent of cryptococcosis in healthy individuals in western North America, despite previous characterization of the fungus as a pathogen in tropical or subtropical regions. As a foundation
Externí odkaz:
https://doaj.org/article/bb93a593590e4e4e833b8232b95e9efd
Autor:
J A Sugui, K J Kwon-Chung
Publikováno v:
Korean Journal of Medical Mycology. 16:81-85
= Abstract = Aspergillus fumigatus, the major etiologic agent of invasive aspergillosis, is a bipolar heterothallic species that produces teleomorphs belonging to the genus Neosartorya. Unlike A. fischeri and other sexual species phylogenetically rel
Publikováno v:
Medical Mycology. 36:165-168
Publikováno v:
Fungal Genetics and Biology. 42:904-913
Cryptococcus neoformans and Cryptococcus gattii are the caus-ative agents of cryptococcal meningoencephalitis and are amenable to genetic manipulations, making them important models of pathogenic fungi. To improve the efficiency of Agrobacterium tume
Publikováno v:
Ophthalmic Plastic & Reconstructive Surgery. 21:71-74
A 47-year-old diabetic man with chronic renal failure presented with a 1-month history of complete ptosis of the left upper eyelid, left proptosis, and left-sided headache. During the course of the patient's care, other significant diagnoses were exc
Publikováno v:
Molecular Microbiology. 55:1222-1232
Cryptococcus neoformans exists in two mating types MATa and MATalpha. Although the morphology, growth characteristics and genetic segregation patterns among MATa and MATalpha strains are indistinguishable in the laboratory, the predominance of MATalp
Publikováno v:
Fungal Genetics and Biology. 41:888-896
Aspergillus fumigatus grows optimally from 37 to 42 degrees C but can grow at temperatures up to 55 degrees C. To study the genetic basis of thermotolerance and its role in virulence of A. fumigatus, temperature sensitive mutants were isolated. One o
Regulatory roles for the homeodomain and C2H2 zinc finger regions of Cryptococcus neoformans Ste12αp
Autor:
Lesley C. Wright, Tania C. Sorrell, R L Tscharke, Yun C. Chang, Christabel F. Wilson, K. J. Kwon-Chung
Publikováno v:
Molecular Microbiology. 53:1385-1396
The STE12alpha gene of Cryptococcus neoformans encodes a protein containing both homeodomain and zinc finger regions. As homeodomains and zinc finger regions are important domains for the function of many transcription factors, we used site-specific