Zobrazeno 1 - 10
of 12
pro vyhledávání: '"K J Else"'
Autor:
M. Glymenaki, A. Barnes, S. O’ Hagan, G. Warhurst, A. J. McBain, I. D. Wilson, D. B. Kell, K. J. Else, S. M. Cruickshank
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Inflammatory bowel disease (IBD) is associated with altered microbiota composition and metabolism, but it is unclear whether these changes precede inflammation or are the result of it since current studies have mainly focused on changes afte
Externí odkaz:
https://doaj.org/article/ba1deb3aefe84912bdbd91350647c562
Autor:
G, Caratti, T, Poolman, R J, Hurst, L, Ince, A, Knight, K, Krakowiak, H J, Durrington, J, Gibbs, K J, Else, L C, Matthews, D W, Ray
Publikováno v:
Scientific Reports
Glucocorticoids (Gcs) are widely prescribed anti-inflammatory compounds, which act through the glucocorticoid receptor (GR). Using an unbiased proteomics screen in lung tissue, we identified the membrane protein caveolin -1 (Cav1) as a direct interac
Autor:
M B, Assas, S E, Levison, M, Little, H, England, L, Battrick, J, Bagnall, J T, McLaughlin, P, Paszek, K J, Else, J L, Pennock
Publikováno v:
Clinical and Experimental Immunology
Summary Infliximab (IFX) has been used repeatedly in mouse preclinical models with associated claims that anti‐inflammatory effects are due to inhibition of mouse tumour necrosis factor (TNF)‐α. However, the mechanism of action in mice remains u
Autor:
R, Bowcutt, L V, Bell, M, Little, J, Wilson, C, Booth, P J, Murray, K J, Else, S M, Cruickshank
Publikováno v:
Parasite Immunology
Alternatively activated macrophages (AAMs) have key roles in the immune response to a variety of gastrointestinal helminths such as Heligmosomoides bakeri and Nippostrongylus brasiliensis. In addition, AAMs have been implicated in the resolution of i
Publikováno v:
The Journal of Immunology. 150:1395-1402
BALB/c mice immunized with radiation attenuated third stage larvae of the filarial nematode Brugia pahangi are strongly immune to challenge infection. Investigation of the profile of cytokines secreted by spleen cells from immune mice stimulated in v
Publikováno v:
Parasite Immunology
Eosinophils have recently been demonstrated capable of localizing to lymph nodes that drain mucosal surfaces, in particular during T helper 2 (Th2) responses. Resistance of mice to infection with the gastrointestinal nematode Trichuris muris depends
Autor:
D, Artis, N E, Humphreys, C S, Potten, N, Wagner, W, Müller, J R, McDermott, R K, Grencis, K J, Else
Publikováno v:
European journal of immunology. 30(6)
The ontogeny and function of gut-associated-lymphoid tissue is known to be critically dependent on the beta7 integrin subfamily. We have investigated the development of intestinal inflammation and pathogen-specific protective immunity to enteric helm
Autor:
K J, Else, F D, Finkelman
Publikováno v:
International journal for parasitology. 28(8)
Laboratory models of intestinal nematode infection have played an important role in developing our understanding of the immune mechanisms that operate against infectious agents. The type of helper T cell response that develops following infection wit
Autor:
K J, Else, R K, Grencis
Publikováno v:
Immunology. 72(4)
A variety of T-cell parameters have been analysed in two H-2 compatible strains of mice, B10.BR and BALB/K, which differ in an absolute fashion in their ability to resist infection with the parasitic nematode Trichuris muris: BALB/K mice expel T. mur
Publikováno v:
Cytokine. 6:581