Zobrazeno 1 - 10
of 199
pro vyhledávání: '"K J, Sweadner"'
Autor:
K J, Sweadner
Publikováno v:
Trends in cardiovascular medicine. 3(1)
The Na,K-ATPase is the only established receptor for cardiac glycosides like digoxin or ouabain. There are now known to be three different isoforms of its principal subunit. These isoforms can differ from one another in their intrinsic affinity for c
Publikováno v:
Investigative ophthalmologyvisual science. 42(11)
Nitric oxide (NO) donors and cholinergic agents decrease intraocular pressure, in part because they induce a decrease in aqueous humor production. Because Na,K-adenosine triphosphatase (ATPase) is involved in aqueous humor formation, this study was c
Autor:
K J, Sweadner, C, Donnet
Publikováno v:
The Biochemical journal. 356(Pt 3)
The crystal structure of SERCA1a (skeletal-muscle sarcoplasmic-reticulum/endoplasmic-reticulum Ca(2+)-ATPase) has recently been determined at 2.6 A (note 1 A = 0.1 nm) resolution [Toyoshima, Nakasako, Nomura and Ogawa (2000) Nature (London) 405, 647-
Autor:
R K, Wetzel, K J, Sweadner
Publikováno v:
Investigative ophthalmologyvisual science. 42(3)
Ion gradients established by NaK-adenosine triphosphatase (ATPase) in the ocular ciliary epithelium (CE) contribute to the production of aqueous humor. Modulation of NaK-ATPase activity in the CE may alter aqueous inflow, aqueous turnover, and intrao
Autor:
P, Martín-Vasallo, R K, Wetzel, L M, García-Segura, E, Molina-Holgado, E, Arystarkhova, K J, Sweadner
Publikováno v:
Glia. 31(3)
The Na,K-ATPase, which catalyzes the active transport of Na(+) and K(+), has two principal subunits (alpha and beta) that have several genetically distinct isoforms. Most of these isoforms are expressed in the nervous system, but certain ones are pre
Autor:
O, Sharabani-Yosef, A, Bak, L, Langzam, Z, Lui, U, Nir, L, Braiman, K J, Sweadner, S R, Sampson
Publikováno v:
Journal of cellular physiology. 180(2)
Studies from this laboratory have shown that the physiological expression of the Na+/K+ pump in primary cultures of rat skeletal muscle increases with development. The molecular mechanisms underlying these changes are not known. Therefore, we have ex
Publikováno v:
Annals of the New York Academy of Sciences. 834
Autor:
E, Arystarkhova, K J, Sweadner
Publikováno v:
The Journal of biological chemistry. 271(38)
Monoclonal antibodies to isoforms of the Na,K-ATPase have become important tools in the study of the enzyme's distribution, physiological roles, and gene regulation, and when their epitopes are defined, they are useful in the study of enzyme structur
Publikováno v:
Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques. 47
Publikováno v:
The Journal of biological chemistry. 270(15)
The topological organization of the Na,K-ATPase alpha subunit is controversial. Detection of extracellular proteolytic cleavage sites would help define the topology, and so attempts were made to find conditions and proteases that would permit digesti