Zobrazeno 1 - 10 of 14 pro vyhledávání: '"K J, Sastry"'
1
Increased inherent intestinal granzyme B expression may be associated with SIV pathogenesis in Asian non-human primates
Autor: Alexander Hutchison, Dorothy E. Lewis, Christopher J. Miller, Nina Tatevian, Aftab A. Ansari, Pramod N. Nehete, Jörn E. Schmitz, Angela Major, K. J. Sastry
Publikováno v: Journal of Medical Primatology. 40:414-426
Background Unlike Asian non-human primates, chronically SIV-infectedAfrican non-human primates (NHP) display a non-pathogenic diseasecourse. The different outcomes may be related to the development of anSIV-mediated breach of the intestinal mucosa in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79b202de679e07087b7c4ef0f191afdc
https://doi.org/10.1111/j.1600-0684.2011.00482.x
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2
Evidence for specific immune response against P210 BCR-ABL in long-term remission CML patients treated with interferon
Autor: Ralph B. Arlinghaus, Moshe Talpaz, J. Q. Guo, Pramod N. Nehete, Takashi Oka, K. J. Sastry, Steven J. Schapiro
Publikováno v: Leukemia. 12:155-163
Interferon-alpha treatment induces complete cytogenetic remission in 25% of Philadelphia chromosome (Ph)-positive chronic myelogenous leukemia (CML) patients. These remissions are durable unlike remissions induced with other therapies and yet residua
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ca4021933365c7558729e5685ddbd7
https://doi.org/10.1038/sj.leu.2400919
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3
Increased inherent intestinal granzyme B expression may be associated with SIV pathogenesis in Asian non-human primates
Autor: A T, Hutchison, J E, Schmitz, C J, Miller, K J, Sastry, P N, Nehete, A M, Major, A A, Ansari, N, Tatevian, D E, Lewis
Publikováno v: Journal of medical primatology. 40(6)
Unlike Asian non-human primates, chronically SIV-infected African non-human primates (NHP) display a non-pathogenic disease course. The different outcomes may be related to the development of an SIV-mediated breach of the intestinal mucosa in the Asi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c1ab9f59ec62c9614c09e085a206eade
https://pubmed.ncbi.nlm.nih.gov/21732950
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4
HIV-1 tat gene induces tumor necrosis factor-beta (lymphotoxin) in a human B-lymphoblastoid cell line
Autor: Klara Totpal, H R Reddy, Bharat B. Aggarwal, R Pandita, K J Sastry
Publikováno v: Journal of Biological Chemistry. 265:20091-20093
The tat protein from human immunodeficiency virus type 1 (HIV-1) activates viral gene expression and is essential for HIV replication in vitro. It has also been shown that the tat gene product specifically inhibits antigen-induced proliferation of hu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a798be884239b43eba8db67eed4e8a0
https://doi.org/10.1016/s0021-9258(17)30473-8
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5
Use of helper T cell-inducing peptides from conserved regions in HIV-1 env in a noncovalent mixture with a CTL-inducing V3-loop peptide for in vivo induction of long-lasting systemic CTL response
Autor: Pramod N. Nehete, K. J. Sastry, Ralph B. Arlinghaus
Publikováno v: Viral immunology. 7(4)
Our previous reports established that immunization of mice in the footpad with a 15-amino acid synthetic peptide (R15K) from the V3 loop region in the envelope protein gp120 of human immunodeficiency virus type 1 (HIV-1) resulted in rapid induction o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9914017c6d6228738e3e91acb7d7f05e
https://pubmed.ncbi.nlm.nih.gov/7576033
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6
Inhibition of human immunodeficiency virus type 1 infection and syncytium formation in human cells by V3 loop synthetic peptides from gp120
Autor: Pramod N. Nehete, Ralph B. Arlinghaus, K. J. Sastry
Publikováno v: Journal of virology. 67(11)
Because V3 loop-specific antibodies have been shown to inhibit human immunodeficiency virus type 1 (HIV-1) infection of human cells and because specific mutations in the V3 loop render the virus ineffective for infection and syncytium formation, we t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::267d6d6f06e974a44951e38c3a37eb52
https://pubmed.ncbi.nlm.nih.gov/7692087
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7
Rapid in vivo induction of HIV-specific CD8+ cytotoxic T lymphocytes by a 15-amino acid unmodified free peptide from the immunodominant V3-loop of GP120
Autor: J. Morkowski, S. Venkatnarayanan, K. J. Sastry, Pramod N. Nehete, Chris D. Platsoucas, Ralph B. Arlinghaus
Publikováno v: Virology. 188(2)
Efforts to generate a vaccine to prevent infection by human immunodeficiency virus (HIV) have focused on inducing neutralizing antibodies. However, cytotoxic T-lymphocyte (CTL) responses are a major immune defense mechanism required for recovery from
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d1eb39c351e946db2aaa3fc94f94b2c
https://pubmed.ncbi.nlm.nih.gov/1316670
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8
HIV-1 tat gene induces tumor necrosis factor-beta (lymphotoxin) in a human B-lymphoblastoid cell line
Autor: K J, Sastry, H R, Reddy, R, Pandita, K, Totpal, B B, Aggarwal
Publikováno v: The Journal of biological chemistry. 265(33)
The tat protein from human immunodeficiency virus type 1 (HIV-1) activates viral gene expression and is essential for HIV replication in vitro. It has also been shown that the tat gene product specifically inhibits antigen-induced proliferation of hu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8176610c7388656058313aee636b9681
https://pubmed.ncbi.nlm.nih.gov/2243081
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