Výsledky vyhledávání

Detection of apoptosis in renal cell carcinoma

Autor: K J, Pienta, J F, Williams

Publikováno v: Methods in molecular medicine. 53

Apoptosis is a selective process of programmed cell death that plays an important role in both physiologic and malignant states. In neoplastic disease, the rate at which a tumor grows depends on cell deletion as well as cell proliferation. It has bee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::418cd3d7406a24cd5ec1f7377ca4e33e
https://pubmed.ncbi.nlm.nih.gov/21318790

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Prostate carcinoma skeletal metastases: cross-talk between tumor and bone

Autor: E T, Keller, J, Zhang, C R, Cooper, P C, Smith, L K, McCauley, K J, Pienta, R S, Taichman

Publikováno v: Cancer metastasis reviews. 20(3-4)

The majority of men with progressive prostate cancer develop metastases with the skeleton being the most prevalent metastatic site. Unlike many other tumors that metastasize to bone and form osteolytic lesions, prostate carcinomas form osteoblastic l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6b1d380e55d3b308cc5e8527d8f60eb7
https://pubmed.ncbi.nlm.nih.gov/12085970

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Chemotherapy in patients with prostate specific antigen-only disease after primary therapy for prostate carcinoma: a phase II trial of oral estramustine and oral etoposide

Autor: H G, Munshi, K J, Pienta, D C, Smith

Publikováno v: Cancer. 91(11)

A Phase II study was initiated to evaluate the effectiveness of an oral regimen of etoposide and estramustine in patients with early recurrent prostate carcinoma.Patients with early recurrent prostate carcinoma as indicated by an increasing prostate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::42d6344f60200ad71a684ba38d98cac5
https://pubmed.ncbi.nlm.nih.gov/11391599

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Evidence for lectin signaling to the nuclear matrix: cellular interpretation of the glycocode

Autor: C H, Chay, K J, Pienta

Publikováno v: Journal of cellular biochemistry. Supplement.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::11d2d34fe3bbb2ec3088d79976ac2487
https://pubmed.ncbi.nlm.nih.gov/11389541

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Establishment and characterization of a new human prostatic cancer cell line: DuCaP

Autor: Y G, Lee, S, Korenchuk, J, Lehr, S, Whitney, R, Vessela, K J, Pienta

Publikováno v: In vivo (Athens, Greece). 15(2)

The lack of appropriate, clinically relevant, cell-based model systems has limited prostate cancer research and the development of new therapeutic modalities. Here we report the isolation and characterization of a new adherent prostate cancer cell li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c9aa825219f9b0c99efebed7b00cb765
https://pubmed.ncbi.nlm.nih.gov/11317521

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A phase II trial of estramustine and etoposide in hormone refractory prostate cancer: A Southwest Oncology Group trial (SWOG 9407)

Autor: K J, Pienta, E I, Fisher, M A, Eisenberger, G M, Mills, J W, Goodwin, J A, Jones, S R, Dakhil, E D, Crawford, M H, Hussain

Publikováno v: The Prostate. 46(4)

The combination of oral estramustine and oral etoposide has generated response rates of 40-50% in patients with hormone refractory prostate cancer in single institution trials. This study tested this regimen in a multi-institutional setting.Fifty-fiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8660e8af4327894cdef2c4bb4b275396
https://pubmed.ncbi.nlm.nih.gov/11241547

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Prostate cancer cell adhesion to quiescent endothelial cells is not mediated by beta-1 integrin subunit

Autor: C R, Cooper, L, McLean, N R, Mucci, P, Poncza, K J, Pienta

Publikováno v: Anticancer research. 20(6B)

Previous studies have reported that tumor cells' adhesion to quiescent endothelial cell is mediated by beta-1 integrins. The aim of this study was to determine the role beta-1 integrins play in prostate cancer cell adhesion to human bone marrow endot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b92cf5d87537199e140662d5214bc409
https://pubmed.ncbi.nlm.nih.gov/11205242

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Preferential adhesion of prostate cancer cells to bone is mediated by binding to bone marrow endothelial cells as compared to extracellular matrix components in vitro

Autor: C R, Cooper, L, McLean, M, Walsh, J, Taylor, S, Hayasaka, J, Bhatia, K J, Pienta

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 6(12)

We have demonstrated previously that the preferential adhesion of prostate cancer cells to human bone marrow endothelial (HBME) cells may contribute to their preferential metastasis to bone. Although a subject of debate, it has been postulated that t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c7c9eabac1f49b81e596be32fee3fbf3
https://pubmed.ncbi.nlm.nih.gov/11156243

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