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Akademický článek

Biochemical and biomechanical properties of the pacemaking sinoatrial node extracellular matrix are distinct from contractile left ventricular matrix.

Autor: Jessica M Gluck, Anthony W Herren, Sergey Yechikov, Hillary K J Kao, Ambereen Khan, Brett S Phinney, Nipavan Chiamvimonvat, James W Chan, Deborah K Lieu

Publikováno v: PLoS ONE, Vol 12, Iss 9, p e0185125 (2017)

Extracellular matrix plays a role in differentiation and phenotype development of its resident cells. Although cardiac extracellular matrix from the contractile tissues has been studied and utilized in tissue engineering, extracellular matrix propert

Externí odkaz: https://doaj.org/article/8d3c7adc6579406b97795fd7c0f345b8

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Akademický článek

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Akademický článek

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Akademický článek

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Factors affecting posttransfusion platelet increments, platelet refractoriness, and platelet transfusion intervals in thrombocytopenic patients

Autor: Thomas S. Kickler, Helen Enright, Sherrill J. Slichter, Edward J. Lee, Jeffrey McCullough, Terry Gernsheimer, G.E. Rodey, Janice G. McFarland, K. J. Kao, Kathryn B. Davis, Robert D. Woodson, Hayden G. Braine, Charles A. Schiffer

Publikováno v: Blood. 105:4106-4114

A variety of patientand product-related factors influenced the outcome of 6379 transfusions given to 533 patients in the Trial to Reduce Alloimmunization to Platelets (TRAP). Responses measured were platelet increments, interval between platelet tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41cdb8d901f0fca403131aee28af07df
https://doi.org/10.1182/blood-2003-08-2724

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Suppression of Interleukin-12 Production through Endogenously Secreted Interleukin-10 in Activated Dendritic Cells: Involvement of Activation of Extracellular Signal-Regulated Protein Kinase

Autor: C.‐Q. Xia, K. J. Kao

Publikováno v: Scandinavian Journal of Immunology. 58:23-32

Our recent study suggested the reverse relationship between the production of interleukin-10 (IL-10) and IL-12 in dendritic cells (DCs) activated by lipopolysaccharide (LPS) or LPS plus interferon (IFN)-gamma. In the present study, a series of experi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f89cf6ba0f3be67f5dc65ef8a6916ca7
https://doi.org/10.1046/j.1365-3083.2003.01268.x

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Monocyte-Derived CD1a+ Dendritic Cells Generated in Two Different Culture Systems: Immunophenotypic and Functional Comparison

Autor: K. J. Kao, C.‐Q. Xia

Publikováno v: Scandinavian Journal of Immunology. 57:324-332

Previous studies demonstrated that CD1a+ dendritic cells (DCs) could not be prepared ex vivo without using fetal calf serum (FCS). Recently, we developed a method of using heparin to induce differentiation of human monocytes into CD1a+ DCs without us

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d176c563f680a95ba7abe893bb9b8b3
https://doi.org/10.1046/j.1365-3083.2003.01238.x

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Structural Studies of a Neuropeptide Precursor Protein with an RGD Proteolytic Site

Autor: Arthur S. Edison, Iris Lindberg, Angus Cameron, Cherian Zachariah, Margery C. Beinfeld, K. J. Kao

Publikováno v: Biochemistry. 40:8790-8799

The snail Lymnaea stagnalis produces a neuropeptide precursor protein that contains seven Arg-Gly-Asp (RGD) sites. These sites are recognized and cleaved by one or more prohormone convertases in the first processing step to yield mature neuropeptides

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45baaaacf14ba72834981bd7fecb8f71
https://doi.org/10.1021/bi010448s

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Platelet transfusions in the neonatal intensive care unit:factors predicting which patients will require multiple transfusions

Autor: Alan D. Hutson, Dale Wright, K. J. Kao, Douglas W. Theriaque, Antonio Del Vecchio, Maria G Garcia, Martha C. Sola, Robert D. Christensen, Bradley H Pollock

Publikováno v: Transfusion. 41:803-808

BACKGROUND: Previous studies suggest that recombinant thrombopoietin (rTPO) will increase platelet production in thrombocytopenic neonates. However, the target populations of neonates most likely to benefit should be defined. Studies suggest that rTP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fdde3840b20b0c978c69d12105335cc
https://doi.org/10.1046/j.1537-2995.2001.41060803.x

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Measurement of Tissue Factor Activity in Whole Blood

Autor: Richard A. Santucci, Thomas S. Kickler, Mark Wilson, Charles R. Spillert, Jonathan Erlich, Nigel Mackman, Joanne Labriola, K J Kao

Publikováno v: Thrombosis and Haemostasis. 83:445-454

SummaryHigh circulating levels of the procoagulant molecule tissue factor (TF) are associated with thrombosis in a variety of diseases including unstable angina, cancer, and sepsis. Currently, there are no clinical assays to measure the level of TF a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::677a80b16ef170e1992059e0a3bfda1f
https://doi.org/10.1055/s-0037-1613835

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