Zobrazeno 1 - 10
of 30
pro vyhledávání: '"K Ilker, Sen"'
Autor:
Trina Mouchahoir, John E. Schiel, Rich Rogers, Alan Heckert, Benjamin J. Place, Aaron Ammerman, Xiaoxiao Li, Tom Robinson, Brian Schmidt, Chris M. Chumsae, Xinbi Li, Anton V. Manuilov, Bo Yan, Gregory O. Staples, Da Ren, Alexander J. Veach, Dongdong Wang, Wael Yared, Zoran Sosic, Yan Wang, Li Zang, Anthony M. Leone, Peiran Liu, Richard Ludwig, Li Tao, Wei Wu, Ahmet Cansizoglu, Andrew Hanneman, Greg W. Adams, Irina Perdivara, Hunter Walker, Margo Wilson, Arnd Brandenburg, Nick DeGraan-Weber, Stefano Gotta, Joe Shambaugh, Melissa Alvarez, X. Christopher Yu, Li Cao, Chun Shao, Andrew Mahan, Hirsh Nanda, Kristen Nields, Nancy Nightlinger, Ben Niu, Jihong Wang, Wei Xu, Gabriella Leo, Nunzio Sepe, Yan-Hui Liu, Bhumit A. Patel, Douglas Richardson, Yi Wang, Daniela Tizabi, Oleg V. Borisov, Yali Lu, Ernest L. Maynard, Albrecht Gruhler, Kim F. Haselmann, Thomas N. Krogh, Carsten P. Sönksen, Simon Letarte, Sean Shen, Kristin Boggio, Keith Johnson, Wenqin Ni, Himakshi Patel, David Ripley, Jason C. Rouse, Ying Zhang, Carly Daniels, Andrew Dawdy, Olga Friese, Thomas W. Powers, Justin B. Sperry, Josh Woods, Eric Carlson, K. Ilker Sen, St John Skilton, Michelle Busch, Anders Lund, Martha Stapels, Xu Guo, Sibylle Heidelberger, Harini Kaluarachchi, Sean McCarthy, John Kim, Jing Zhen, Ying Zhou, Sarah Rogstad, Xiaoshi Wang, Jing Fang, Weibin Chen, Ying Qing Yu, John G. Hoogerheide, Rebecca Scott, Hua Yuan
Publikováno v:
Journal of the American Society for Mass Spectrometry. 33:1659-1677
The multi-attribute method (MAM) was conceived as a single assay to potentially replace multiple single-attribute assays that have long been used in process development and quality control (QC) for protein therapeutics. MAM is rooted in traditional p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fbb68de4c53ee4678b9e74066d51588
https://doi.org/10.1021/jasms.2c00129
https://doi.org/10.1021/jasms.2c00129
Autor:
Irina Perdivara, Ben Niu, Kim F. Haselmann, St John Skilton, Anthony Leone, Gregory O. Staples, Carsten P. Sønksen, Helena Maria Barysz, Andrew Hanneman, Chun Shao, Rebecca Scott, Anders Lund, Carly Daniels, Michael Jahn, Da Ren, Nunzio Sepe, K. Ilker Sen, Zoran Sosic, David Ripley, Jing Zhen, Margo Wilson, Melissa Alvarez, John G Hoogerheide, Xinbi Li, Harini Kaluarachchi, Josh Woods, Wenqin Ni, Albrecht Gruhler, Keith A. Johnson, Arnd Brandenburg, Kristen Nields, Michelle Busch, Douglas D. Richardson, Yan Wang, Ahmet Cansizoglu, Xiaoxiao Li, Greg W Adams, Simon Letarte, Joe Shambaugh, Hua Yuan, Trina Mouchahoir, Tom Robinson, Xiaoshi Wang, Nancy S. Nightlinger, Alexander Julian Veach, Chris Chumsae, Eric Carlson, Dongdong Wang, Sean Shen, Jing Fang, Wei Wu, Stefano Gotta, Justin B. Sperry, Hirsh Nanda, X. Christopher Yu, Sibylle Heidelberger, Bhumit A. Patel, Jihong Wang, Sean McCarthy, Himakshi Patel, Thomas N. Krogh, Hunter Walker, Olga V. Friese, Daniela Tizabi, Yali Lu, Kristin Boggio, Ernest L. Maynard, Rich Rogers, Ying Zhou, Nick DeGraan-Weber, John E. Schiel, Weibin Chen, Jason C. Rouse, Li Tao, Thomas W. Powers, John Kim, Xu Guo, Bo Yan, Gabriella Leo, Ying Zhang, Oleg V. Borisov, Ying Qing Yu, Martha Stapels, Wael Yared, Yan-Hui Liu, Alan Heckert, Sarah Rogstad, Li Zang, Aaron Ammerman, Li Cao, Benjamin J. Place, Richard Ludwig, Anton V. Manuilov, Andrew Mahan, Andrew Dawdy, Yi Wang, Brian Schmidt, Peiran Liu
Publikováno v:
Journal of the American Society for Mass Spectrometry. 32:913-928
The Multi-Attribute Method (MAM) Consortium was initially formed as a venue to harmonize best practices, share experiences, and generate innovative methodologies to facilitate widespread integration of the MAM platform, which is an emerging ultra-hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4baf4a0ab2df01bdb011465e0f168239
https://doi.org/10.1021/jasms.0c00415
https://doi.org/10.1021/jasms.0c00415
Autor:
Alain Beck, Elsa Wagner, K. Ilker Sen, Olivier Colas, Stuart Pengelley, Anja Resemann, D. Suckau, Waltraud Evers, Eckhard Belau, Wilfred H. Tang
Publikováno v:
Therapeutic Antibodies ISBN: 9781071614495
Biopharmaceutical sequences can be well confirmed by multiple protease digests-e.g., trypsin, elastase, and chymotrypsin-followed by LC-MS/MS data analysis. High quality data can be used for de novo sequencing as well. PASEF (Parallel Accumulation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59f8848af2db32af50386b0325f0bf80
https://doi.org/10.1007/978-1-0716-1450-1_12
https://doi.org/10.1007/978-1-0716-1450-1_12
Autor:
Detlev, Suckau, Waltraud, Evers, Eckhard, Belau, Stuart, Pengelley, Anja, Resemann, Wilfred, Tang, K Ilker, Sen, Elsa, Wagner, Olivier, Colas, Alain, Beck
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2313
Biopharmaceutical sequences can be well confirmed by multiple protease digests-e.g., trypsin, elastase, and chymotrypsin-followed by LC-MS/MS data analysis. High quality data can be used for de novo sequencing as well. PASEF (Parallel Accumulation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e6d3e4246f18e4c5a9a96810abdd1594
https://pubmed.ncbi.nlm.nih.gov/34478140
https://pubmed.ncbi.nlm.nih.gov/34478140
Autor:
Doron Kletter, Marshall Bern, Yong J. Kil, Gary M. Wilson, Eric Carlson, Wilfred H. Tang, Abhishek Roushan, K. Ilker Sen
Publikováno v:
Molecular & Cellular Proteomics : MCP
Glycopeptides in peptide or digested protein samples pose a number of analytical and bioinformatics challenges beyond those posed by unmodified peptides or peptides with smaller posttranslational modifications. Exact structural elucidation of glycans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9eaff547a924cf4753760279f93987
http://europepmc.org/articles/PMC8724605
http://europepmc.org/articles/PMC8724605
Autor:
Steven P. Schwendeman, Jukyung Kang, Solomon Z. Okbazghi, Yuwei Tian, Anna Schwendeman, Michael J. Ford, Eric Carlson, K. Ilker Sen, Thomas J. Tolbert, Karthik Pisupati, Alexander Benet, Brandon T. Ruotolo, Sergei Saveliev
Publikováno v:
mAbs. 9:1197-1209
Remsima™ (infliximab) is the first biosimilar monoclonal antibody (mAb) approved by the European Medical Agency and the US Food and Drug Administration. Remsima™ is highly similar to its reference product, Remicade®, with identical formulation c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3168c25bc5d17c44f3ed1e497bae1299
https://doi.org/10.1080/19420862.2017.1347741
https://doi.org/10.1080/19420862.2017.1347741
Autor:
Darryl Davis, Christopher H. Becker, Yong J. Kil, Berk Ozoglu, Wilfred H. Tang, K. Ilker Sen, Beatrix Ueberheide, Marshall Bern, Shruti Nayak
Publikováno v:
Journal of the American Society for Mass Spectrometry. 28:803-810
Applications of antibody de novo sequencing in the biopharmaceutical industry range from the discovery of new antibody drug candidates to identifying reagents for research and determining the primary structure of innovator products for biosimilar dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec135c14795963ae189ac7090d3a7f12
https://doi.org/10.1007/s13361-016-1580-0
https://doi.org/10.1007/s13361-016-1580-0
Autor:
Anna Schwendeman, Jukyung Kang, Zeynab Izadi Najafabadi, Troy Halseth, K. Ilker Sen, Michael J. Ford, Daniel D. Vallejo, Brandon T. Ruotolo
Publikováno v:
Analytical and bioanalytical chemistry. 412(3)
Biosimilars are highly similar to, but not identical with, their originator products. As a result, structural differences between originators and biosimilars can be difficult to detect and characterize without the appropriate analytical tools. Theref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea0ed3ba1b8f6373335d4c96673acb88
https://pubmed.ncbi.nlm.nih.gov/31853605
https://pubmed.ncbi.nlm.nih.gov/31853605
Autor:
Tyler S. Hageman, Jill Coghlan, Derek R. White, K. Ilker Sen, Anna Schwendeman, Jukyung Kang, Steven P. Schwendeman, Sergei Saveliev, Alexander Benet, Michael J. Ford, Thomas J. Tolbert, Brandon T. Ruotolo, Sang Yeop Kim, David D. Weis, Daniel D. Vallejo
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 146
Biosimilars are poised to reduce prices and increase patient access to expensive, but highly effective biologic products. However, questions still remain about the degree of similarity and scarcity of information on biosimilar products from outside o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5789c0cb739018af019c6aa816cf0f7b
https://pubmed.ncbi.nlm.nih.gov/31841688
https://pubmed.ncbi.nlm.nih.gov/31841688
Autor:
Jie Zhang, David M. Lubman, Qing Yu, St John Skilton, Jianhui Zhu, Lingjun Li, Marshall Bern, Mingrui An, K. Ilker Sen, Zhengwei Chen, Jing Wu
Publikováno v:
Journal of Proteome Research.
Intact N-glycopeptide analysis remains challenging due to the complexity of glycopeptide structures, low abundance of glycopeptides in protein digests, and difficulties in data interpretation/quantitation. Herein, we developed a workflow that involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ca1c7144768b179fb57bfb35add6c8
https://doi.org/10.1021/acs.jproteome.8b00654
https://doi.org/10.1021/acs.jproteome.8b00654