Zobrazeno 1 - 10
of 10
pro vyhledávání: '"K I, Stosman"'
Autor:
K. V. Sivak, K. I. Stosman, E. Yu. Kalinina, M. M. Lyubishin, Ya. R. Orshanskaya, T. N. Savateeva-Lyubimova, S. B. Kazakova, D. M. Fedoseeva, A. S. Nazarov, E. I. Radion, S. M. Yudin, A. A. Keskinov, V. V. Makarov, V. S. Yudin, A. O. Zheltukhin, P. O. Vorobyev, D. V. Kochetkov, G. V. Ilyinskaya, A. V. Lipatova, P. M. Chumakov
Publikováno v:
Безопасность и риск фармакотерапии, Vol 0, Iss 0 (2022)
INTRODUCTION. Developing novel medicines based on non-pathogenic enterovirus strains exhibiting oncotropic and oncolytic properties represents an up-to-date and safe approach to complex cancer treatment and postoperative metastasis prevention. Safety
Externí odkaz:
https://doaj.org/article/c3aafa14645e435fa0f9881cad8c8c77
Autor:
L. I. Dyakova, G. I. Sidorin, G. V. Shestova, E. P. Zatsepin, L. V. Lukovnikova, B. S. Litvintsev, K. I. Stosman
Publikováno v:
Toxicological Review. :34-38
The paper presents the results of a study on the possibility of toxic effects developing in contact with the antitumor drug – lysomustine - to assess the health risk in the manufacture of the finished dosage form and its use. The work was performed
Autor:
N. B. Viktorov, A. A. Muzhikyan, Daria D Vaulina, N. A. Gomzina, K. V. Sivak, K. I. Stosman, A. G. Alexandrov
Publikováno v:
Russian Journal of Bioorganic Chemistry. 45:425-429
The synthesis of two derivatives of lignan 4'-O-methylhonokiol (MH), i.e., 4'-methoxy-5-propyl-1,1'-biphenyl-2-ol (III) and 4'-(2-fluoroethoxy)-2-hydroxy-5-propyl-1,1'-biphenyl (VI) has been described. Derivative (VI) demonstrates the highest anti-in
Autor:
K. V. Sivak, T A Rassokha, Ya R Orshanskaya, K I Stosman, E E Lesiovskaya, N. N. Kuzmich, T. N. Savateeva-Lubimova, A. G. Aleksandrov
Publikováno v:
Bulletin of experimental biology and medicine. 169(6)
The effects of TLR4 blocker on blood cell morphology, concentrations proinflammatory cytokines, and functional state of the liver and kidneys were studied in outbred male rats (n=60) after intravenous injection of 20 mg/kg LPS isolated from opportuni
Publikováno v:
Medicо-Biological and Socio-Psychological Problems of Safety in Emergency Situations. :73-79
Relevance. Depleted uranium (DU) is actively used in many industries. The problems of the safety of personnel employed at industrial facilities of this kind continue to remain relevant. Experimental studies have shown the toxicity of uranium compound
Publikováno v:
Medicо-Biological and Socio-Psychological Problems of Safety in Emergency Situations. :95-100
Relevance.Intoxication by depleted uranium is possible at uranium mining and processing enterprises, as well as during military conflicts.Intention.To identify possible immunological disorders that develop after acute exposure to depleted uranium in
Publikováno v:
Russian Journal of Occupational Health and Industrial Ecology. :685-686
Working in contact with nitroglycerine, TNT, RDX, oxygenatom, organic solvents, recorded elevated levels of cortisol in the blood. In contact with metals, their blood levels and cortisol levels did not differ from the average values of the profession
Publikováno v:
Russian Journal of Occupational Health and Industrial Ecology. :764-764
Acute exposure of depleted uranium leads to dysfunction of lymphocytes, their quantitative characteristics, an increase the proportion of apoptotic and necrotic cells. The immunological changes were transitory.
Autor:
T N, Savateeva-Liubimova, E E, Lesiovskaia, K V, Sivak, K I, Stosman, G S, Stroĭkova, T A, Rassokha, L I, Rudenko
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 74(2)
Optimal combination of chlorhexidine bigluconate with ascorbic acid, succinic acid, and zinc oxide was found as a result of comparative trials. The composition shows antioxidative effects and is capable of initiating antibody producing and phagocytos
Autor:
T N, Savateeva-Liubimova, E E, Lesiovskaia, K V, Sivak, K I, Stosman, M K, Shevchuk, S G, Dagaev, A V, Savateev, A L, Kovalenko, A Iu, Petrov, D S, Sukhanov
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 73(11)
Preclinical safety of reamberin, a preparation of succinic acid intended for the treatment of patients with shock conditions of different etiology, and remaxol a drug intended for the treatment of patients with liver dysfunction caused by acute intox