Zobrazeno 1 - 10
of 12
pro vyhledávání: '"K I, Matthaei"'
Publikováno v:
ResearcherID
Interleukin 5 is expressed in type 2 T lymphocytes and has a key role in driving the differentiation, recruitment and activation of eosinophils. Mice with a null mutation in the interleukin 5 gene (IL-5 -/- mice) have altered type 2 immune responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23236b1312c434bbcf2992afa500f241
https://doi.org/10.1530/reprod/120.2.423
https://doi.org/10.1530/reprod/120.2.423
Publikováno v:
Journal of Medical Microbiology. 46:987-997
Summary Subtractive hybridisation was used to screen for and identify conserved DNA sequences associated with clinical, clonal populations of Staphylococcus aureus. DNA from S. aureus strain ISP8 (a clinical isolate) was digested with TaqI and hybrid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d7869bf9ac7a36bf062db24d6428cf
https://doi.org/10.1099/00222615-46-12-987
https://doi.org/10.1099/00222615-46-12-987
Publikováno v:
Thrombosis and haemostasis. 85(3)
Gz is one of nine G proteins identified in platelets and its role in these cells is unknown. Our laboratory has generated a mouse deficient in the Gz-alpha gene in the hope of determining its in vivo function. Bleeding times from the tail tip of Gzal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9503e6360b66fb5cba4d2d080472253e
https://pubmed.ncbi.nlm.nih.gov/11307826
https://pubmed.ncbi.nlm.nih.gov/11307826
Autor:
P S, Foster, A W, Mould, M, Yang, J, Mackenzie, J, Mattes, S P, Hogan, S, Mahalingam, A N, Mckenzie, M E, Rothenberg, I G, Young, K I, Matthaei, D C, Webb
Publikováno v:
Immunological reviews. 179
In this review we identify the elemental signals that regulate eosinophil accumulation in the allergic lung. We show that there are two interwoven mechanisms for the accumulation of eosinophils in pulmonary tissues and that these mechanisms are linke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3fdf1f3fdd3fea38c0f5e8aeae0e1957
https://pubmed.ncbi.nlm.nih.gov/11292021
https://pubmed.ncbi.nlm.nih.gov/11292021
Publikováno v:
Parasite immunology. 23(1)
To identify the role of signal transducer and activator of transcription factor 6 (Stat6) in the development of intestinal goblet cell hyperplasia during nematode infection, we compared the number of goblet cells in Stat6 deficient (Stat6 -/-) mice w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d7c85ba0e77b29bcc2e310bd7efd4f6
https://pubmed.ncbi.nlm.nih.gov/11136476
https://pubmed.ncbi.nlm.nih.gov/11136476
Publikováno v:
European journal of immunology. 30(6)
IL-5 is generally regarded as a Th2 cytokine involved in eosinophil maturation and function and in B cell growth and antibody production, but without any well-established effects on T cells. Early reports suggested that IL-5 could stimulate the produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66c38f52b6ffe7b05f53d4103f2f41ac
https://pubmed.ncbi.nlm.nih.gov/10898511
https://pubmed.ncbi.nlm.nih.gov/10898511
Autor:
I A, Hendry, K L, Kelleher, S E, Bartlett, K J, Leck, A J, Reynolds, K, Heydon, A, Mellick, D, Megirian, K I, Matthaei
Publikováno v:
Brain research. 870(1-2)
Our laboratory has generated a mouse deficient in the alpha (alpha) subunit of the G protein, G(z), (G(z alpha)) gene and we have examined the involvement of G(z alpha) in spinal and supraspinal analgesia and tolerance mechanisms. Spinal analgesia wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9247a909d0230d031234904ab59a2c27
https://pubmed.ncbi.nlm.nih.gov/10869496
https://pubmed.ncbi.nlm.nih.gov/10869496
Publikováno v:
Laboratory animal science. 48(2)
The enormous cost of eliminating mouse hepatitis virus (MHV) from a mouse colony demands that a confirmed etiologic diagnosis be made to justify the necessary remedial action. We describe an outbreak of MHV in nude mice in which histopathologic findi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5044714c62d468ff1a9045713f8b747
https://pubmed.ncbi.nlm.nih.gov/10090004
https://pubmed.ncbi.nlm.nih.gov/10090004
Publikováno v:
American journal of respiratory and critical care medicine. 157(1)
Although activated CD4+ T cells have been implicated in the pathogenesis of asthma, the direct contribution of this leukocyte to the induction of aeroallergen-induced bronchial hyperreactivity and lung damage is unknown. In the present investigation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::176070e9197094a848a58eda9aaea2a9
https://pubmed.ncbi.nlm.nih.gov/9445302
https://pubmed.ncbi.nlm.nih.gov/9445302
Autor:
C J, Simeonovic, M J, Townsend, J D, Wilson, K U, McKenzie, A J, Ramsay, K I, Matthaei, D A, Mann, I G, Young
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 158(5)
The rejection of neovascularized pig proislet (islet precursor) xenografts in mice is a CD4 T cell-dependent process involving invasion of the graft site mainly by host CD4 T cells and eosinophils. We previously identified CD4 T cell-dependent enhanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28dca35e467267c90276249633b6dea9
https://pubmed.ncbi.nlm.nih.gov/9037001
https://pubmed.ncbi.nlm.nih.gov/9037001