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pro vyhledávání: '"K Husgafvel-Pursiainen"'
Akademický článek
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Autor:
K. Linnainmaa, Karin Mattson, K Husgafvel-Pursiainen, H Vainio, Sirkku T. Saarikoski, K Koskinen, Ari Hirvonen
Publikováno v:
JNCI Journal of the National Cancer Institute. 88:1853-1856
Background Humans vary in their ability to metabolize endogenous and exogenous compounds. Glutathione S-transferases (GSTs) and N-acetyltransferases (NATs) are enzymes involved in the detoxification of hazardous agents. The GSTM1 and GSTT1 genes exhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec635cf8550fa1741236496d58c856d
https://doi.org/10.1093/jnci/88.24.1853
https://doi.org/10.1093/jnci/88.24.1853
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
L, Laforest, H, Wikman, S, Benhamou, S T, Saarikoski, C, Bouchardy, A, Hirvonen, P, Dayer, K, Husgafvel-Pursiainen
Publikováno v:
European journal of cancer (Oxford, England : 1990). 36(14)
Individual susceptibility to smoking-related cancers is proposed to partly depend on a genetically determined ability to metabolise tobacco carcinogens. We previously reported on the association between the activity of the xenobiotic-metabolising enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b8f326776468e403ada4bb4b13a3ea7
https://pubmed.ncbi.nlm.nih.gov/10974631
https://pubmed.ncbi.nlm.nih.gov/10974631
Autor:
S T, Saarikoski, F, Sata, K, Husgafvel-Pursiainen, M, Rautalahti, J, Haukka, O, Impivaara, J, Järvisalo, H, Vainio, A, Hirvonen
Publikováno v:
Pharmacogenetics. 10(1)
Some 3-10% of Caucasians are deficient in CYP2D6 metabolism (poor metabolizers), due to inheritance of two defective alleles, whereas amplification of the CYP2D6 gene results in ultrarapid metabolism in 1-2% of Caucasian populations. To examine the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::caf89e70b5c1bb9dc9593f986b459a3d
https://pubmed.ncbi.nlm.nih.gov/10739167
https://pubmed.ncbi.nlm.nih.gov/10739167
Autor:
S T, Saarikoski, A, Voho, M, Reinikainen, S, Anttila, A, Karjalainen, C, Malaveille, H, Vainio, K, Husgafvel-Pursiainen, A, Hirvonen
Publikováno v:
International journal of cancer. 77(4)
Glutathione S-transferases (GSTs) are known to take part in detoxification of many potentially carcinogenic compounds. Therefore, polymorphisms of the GST genes have been considered as potentially important modifiers of individual risk of environment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ed4ff7be580bbd9e822f19f5b3d65c70
https://pubmed.ncbi.nlm.nih.gov/9679751
https://pubmed.ncbi.nlm.nih.gov/9679751
Publikováno v:
International journal of cancer. 77(1)
Cytochrome P4501A1 (CYP1A1) is involved in the bioactivation of polycyclic aromatic hydrocarbons into their reactive epoxide metabolites. CYP1A1 is considered to be important with regard to individual susceptibility to lung cancer since phenotypic an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a56de4f377f386dade9ee42b1da7a41
https://pubmed.ncbi.nlm.nih.gov/9639391
https://pubmed.ncbi.nlm.nih.gov/9639391
Autor:
A M, Björkqvist, K, Husgafvel-Pursiainen, S, Anttila, A, Karjalainen, L, Tammilehto, K, Mattson, H, Vainio, S, Knuutila
Publikováno v:
Genes, chromosomescancer. 22(1)
We performed a comparative genomic hybridization study on 25 samples of adenocarcinoma and 19 samples of squamous cell carcinoma of the lung to detect recurrent changes in the genetic material. DNA copy number changes were found in 16 squamous cell c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e32e8f4baaf3cf89cc1ae7167fbd6d28
https://pubmed.ncbi.nlm.nih.gov/9591638
https://pubmed.ncbi.nlm.nih.gov/9591638
Autor:
S, Roth, T, Partanen, T, Suitiala, S, Anttila, A, Ojajärvi, K, Hemminki, H, Vainio, K, Husgafvel-Pursiainen
Publikováno v:
International journal of cancer. 73(4)
Occupational exposure to gasoline has been identified in several studies as a risk factor for renal-cell cancer. Cases of renal-cell cancer with and without work-related exposure to gasoline or gasoline and diesel fuel were studied for the presence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c909101e4bfbcc19ca16f0e69cd5945
https://pubmed.ncbi.nlm.nih.gov/9389561
https://pubmed.ncbi.nlm.nih.gov/9389561
Autor:
H, Vainio, K, Husgafvel-Pursiainen
Publikováno v:
British journal of hospital medicine. 56(4)
Molecular epidemiology supplies information on various stages of the multistep process of carcinogenesis and allows identification of biological markers that may indicate an increased risk of cancer. These markers have an established position in occu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e3c32a3ce965a1705d766a4813b832c
https://pubmed.ncbi.nlm.nih.gov/8872345
https://pubmed.ncbi.nlm.nih.gov/8872345