Zobrazeno 1 - 10
of 39
pro vyhledávání: '"K H Lehr"'
Publikováno v:
Drug Metabolism and Drug Interactions. 13
After oral administration of a single dose of 200 mg of levofloxacin and 400 mg racemic mixture of ofloxacin to 6 healthy male volunteers in a double-blind, randomised cross-over study, concentrations of the unchanged isomers were determined at vario
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6a898fd4d78a462b87b5b177119c4c1
https://doi.org/10.1515/dmdi.1996.13.1.57
https://doi.org/10.1515/dmdi.1996.13.1.57
Publikováno v:
The Journal of antimicrobial chemotherapy. 37(1)
The activities of levofloxacin and ofloxacin against 22 clinical legionella isolates was determined by microbroth dilution susceptibility testing. Growth inhibition of two Legionella pneumophila strains grown in guinea pig alveolar macrophages by lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a3fd26330bad536019a3fc21343f93
https://pubmed.ncbi.nlm.nih.gov/8647752
https://pubmed.ncbi.nlm.nih.gov/8647752
Publikováno v:
Drug metabolism and drug interactions. 13(1)
Glimepiride is a new sulphonylurea which is eliminated by the formation of a hydroxy-metabolite (hydroxy-gli) and a carboxymetabolite (carboxy-gli). Animal studies have shown hydroxy-gli to exhibit some hypoglycaemic effects while carboxy-gli does no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::275213f98f06334ee3f356a9496de063
https://pubmed.ncbi.nlm.nih.gov/8902432
https://pubmed.ncbi.nlm.nih.gov/8902432
Publikováno v:
Drug Metabolism and Drug Interactions. 11
Twelve healthy fasting male volunteers received a single 1.0 mg dose of glimepiride either as an intravenous injection over one minute or as a tablet. Blood and urine samples were taken before drug administration and afterwards for up to 24 hours (bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd4e993741944f85602be6bb622507b
https://doi.org/10.1515/dmdi.1994.11.4.331
https://doi.org/10.1515/dmdi.1994.11.4.331
Publikováno v:
Drug metabolism and drug interactions. 11(4)
Twelve healthy fasting male volunteers received glimepiride in 1, 2, 4 or 8 mg single oral doses. On the days when glimepiride was taken, the subjects were given a standardised carbohydrate diet (18 bread exchange units) and drank 125 ml of water hou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d1ac93e897b007d4f272774e0ec60f5
https://pubmed.ncbi.nlm.nih.gov/12369757
https://pubmed.ncbi.nlm.nih.gov/12369757
Publikováno v:
Clinical pharmacology and therapeutics. 54(4)
Cefpirome is eliminated primarily by renal excretion, compelling dosage reduction in kidney failure. We studied the elimination kinetics after intravenous administration of 1 gm cefpirome in patients undergoing hemodialysis (n = 9) and after intraven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871edc9a28b7678497fb4b3304efa7ea
https://pubmed.ncbi.nlm.nih.gov/8222482
https://pubmed.ncbi.nlm.nih.gov/8222482
Publikováno v:
Current problems in dermatology. 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4349fedd2f0a31fefb9f83e4ade8a96b
https://pubmed.ncbi.nlm.nih.gov/8299368
https://pubmed.ncbi.nlm.nih.gov/8299368
Publikováno v:
European journal of clinical pharmacology. 42(6)
The pharmacokinetic and pharmacodynamic interactions between metamizole (dipyrone) and furosemide were investigated in 9 of 12 healthy female subjects able to complete the study. They received oral metamizole 3 x 1 g for 3 days or placebo (cross-over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07643b80eb7d97e680ca3f694d76767d
https://pubmed.ncbi.nlm.nih.gov/1623899
https://pubmed.ncbi.nlm.nih.gov/1623899
Autor:
K. H. Lehr, Th. Höhler, Günther Hochhaus, Hartmut Derendorf, Jürgen Barth, Helmut Möllmann, C. Möllmann
Publikováno v:
European Journal of Pharmacology. 183:2134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4ac00ea37f6dc13785aaeb728e7be69
https://doi.org/10.1016/0014-2999(90)93655-a
https://doi.org/10.1016/0014-2999(90)93655-a