Výsledky vyhledávání - "K H, Fritzemeier"

Differential Effects of 17β-Estradiol and of Synthetic Progestins on Aldosterone-Salt–Induced Kidney Disease

Autor: Hartmut Blode, Georg Ertl, Melanie Muehlfelder, Susan A. Elmore, Kai Hu, Robert R. Maronpot, Theo Pelzer, Paula-Anahi Arias-Loza, K. H. Fritzemeier, Christa Hegele-Hartung

Publikováno v: Toxicologic Pathology. 37:969-982

Elevated mineralocorticoid levels and female sex hormones have been shown to confer opposing effects on renal injury, but their combined effects are still unknown. Objective: Identify the function of estrogens and of different synthetic progestins on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e012d7d45bb3407dde83d61156981e6a
https://doi.org/10.1177/0192623309350475

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Ligand-dependent activation of ER lowers blood pressure and attenuates cardiac hypertrophy in ovariectomized spontaneously hypertensive rats

Autor: Johann Bauersachs, K. H. Fritzemeier, Christa Hegele-Hartung, Theo Pelzer, Julian Widder, Ludwig Neyses, Christine von Poser-Klein, Georg Ertl, Virginija Jazbutyte, Kai Hu, Paula Anahi Arias-Loza, Vijayakumar Govindaraj

Publikováno v: Cardiovascular Research. 77:774-781

The biological effects of oestrogens are mediated by two different oestrogen receptor (ER) subtypes, ERalpha and ERbeta, which might play different, redundant, or opposing roles in cardiovascular disease. Previously, we have shown that the selective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a255fd2873baf0a30d55cf970a5134
https://doi.org/10.1093/cvr/cvm081

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Raloxifene blocks estradiol induction of the serotonin transporter and 5-hydroxytryptamine2A receptor in female rat brain

Autor: Roberta Rosie, George Fink, Barbara E.H. Sumner, K.E. Grant, Ch. Hegele-Hartung, K. H. Fritzemeier

Publikováno v: Neuroscience Letters. 417:95-99

Sex steroids have potent effects on mood, mental state and cognition. Our previous findings and those of others suggest that these effects may be due at least in part to estradiol actions on central serotonergic mechanisms. Specifically, estradiol-17

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f245ab2a47a788e671461c121d58237c
https://doi.org/10.1016/j.neulet.2007.02.039

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The estrogen receptor-α agonist 16α-LE2 inhibits cardiac hypertrophy and improves hemodynamic function in estrogen-deficient spontaneously hypertensive rats

Autor: Jenny Muck, Stephan Segerer, Theo Pelzer, K. H. Fritzemeier, Christa Hegele-Hartung, Ludwig Neyses, Virginija Jazbutyte, Andreas Bonz, Peter Nordbeck, Georg Ertl, Matthias Nahrendorf, Kai Hu

Publikováno v: Cardiovascular Research. 67:604-612

Cardiac mass increases with age and with declining estradiol serum levels in postmenopausal women. Although the non-selective estrogen receptor-alpha and -beta agonist 17beta-estradiol attenuates cardiac hypertrophy in animal models and in observatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9af86e27299fc42e990b6f3ff276ef
https://doi.org/10.1016/j.cardiores.2005.04.035

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A prostaglandin E2 receptor antagonist prevents pregnancies during a preclinical contraceptive trial with female macaques

Autor: B. Lindenthal, Mary B. Zelinski, Jessica E. Stanley, U. Fuhrmann, Nico Braeuer, Marina C. Peluffo, A. Rotgeri, Melinda J. Murphy, Tiffany Adevai, Jon D. Hennebold, B. Buchmann, Richard L. Stouffer, K. H. Fritzemeier

STUDY QUESTION Can administration of a prostaglandin (PG) E2 receptor 2 (PTGER2) antagonist prevent pregnancy in adult female monkeys by blocking periovulatory events in the follicle without altering menstrual cyclicity or general health? SUMMARY ANS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca7c900829a634c22c37fa1f013c1876
https://europepmc.org/articles/PMC4059334/

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Impact of estradiol, estrogen receptor subtype specific agonists and genistein on food intake, body weight, and glucose metabolism in leptin resistant ovariectomized Zucker diabetic fatty rats

Autor: C Weigt, P. Diel, F Hülsemann, U Flenker, T. Hertrampf, K. H. Fritzemeier

Publikováno v: Experimental and Clinical Endocrinology & Diabetes. 121

The leptin resistant female Zucker diabetic fatty (ZDF fa/fa) rats are described to be hyperphagic and obese, but compared to its male counterparts they remain euglycaemic. Since estrogens are known to affect glucose metabolism we investigated the lo

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https://doi.org/10.1055/s-0033-1336633

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Sexual dimorphism of steroid hormone receptor messenger ribonucleic acid expression and hormonal regulation in rat vascular tissue

Autor: Rudolf Knauthe, K. H. Fritzemeier, Christa Hegele-Hartung, P. Diel, A Engelhaupt

Publikováno v: Endocrinology. 137:3220-3227

Evidence has accumulated suggesting that steroid hormones have a direct effect on the vascular system. Of special interest is the protective effect of estrogens against cardiovascular diseases. One of the aims of the present study was to investigate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24715270323f4797a41c85ff73509135
https://doi.org/10.1210/endo.137.8.8754743

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Identification of estrogen regulated genes in Fe33 rat hepatoma cells by differential display polymerase chain reaction and their hormonal regulation in rat liver and uterus

Autor: A. Walter, P. Diel, K. H. Fritzemeier, Ch. Hegele-Hartung, Rudolf Knauthe

Publikováno v: The Journal of Steroid Biochemistry and Molecular Biology. 55:363-373

We applied the differential display RT-PCR (ddRT-PCR) technology to identify estrogen-regulated hepatic genes in the estrogen receptor expressing rat hepatoma cell line Fe33. Three genes of known sequences were detected by the ddRT-PCR approach: IGF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9cf06e6e1ed9f7acfa7866076eebe5a
https://doi.org/10.1016/0960-0760(95)00186-7

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Pharmacology and clinical use of sex steroid hormone receptor modulators

Autor: A, Cleve, K-H, Fritzemeier, B, Haendler, N, Heinrich, C, Möller, W, Schwede, T, Wintermantel

Publikováno v: Handbook of experimental pharmacology. (214)

Sex steroid receptors are ligand-triggered transcription factors. Oestrogen, progesterone and androgen receptors form, together with the glucocorticoid and mineralocorticoid receptors, a subgroup of the superfamily of nuclear receptors. They share a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3d5cd42c24c10d77c4c63e7c07ad4200
https://pubmed.ncbi.nlm.nih.gov/23027466

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Pharmacology and Clinical Use of Sex Steroid Hormone Receptor Modulators

Autor: A. Cleve, B. Haendler, Tim Wintermantel, C. Möller, K.-H. Fritzemeier, Wolfgang Schwede, Nikolaus Heinrich

Publikováno v: Sex and Gender Differences in Pharmacology ISBN: 9783642307256

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d5c66b10bd90b1c9ee1dc40f45d42cd5
https://doi.org/10.1007/978-3-642-30726-3_24

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