Zobrazeno 1 - 10
of 29
pro vyhledávání: '"K H, Buetow"'
Autor:
N Siegelmann-Danieli, K H Buetow
Publikováno v:
British Journal of Cancer
The activity of the aromatase enzyme, which converts androgens into oestrogens and has a major role in regulating oestrogen levels in the breast, is thought to be a contributing factor in the development of breast cancer. We undertook this study to a
Autor:
K. H Buetow
Publikováno v:
AACR Education book. 2008:537-539
Autor:
B R, Balsara, J, Pei, A, De Rienzo, D, Simon, A, Tosolini, Y Y, Lu, F M, Shen, X, Fan, W Y, Lin, K H, Buetow, W T, London, J R, Testa
Publikováno v:
Genes, chromosomescancer. 30(3)
Comparative genomic hybridization (CGH) analysis was used to identify chromosomal imbalances in 52 human primary hepatocellular carcinomas (HCCs). The most prominent changes were gains of part or all of chromosome arms 8q (83% of cases) and 1q (73%)
Publikováno v:
International journal of cancer. 77(4)
Metastasis is one of the most important and complex processes in human neoplastic disease. A large number of both positive and negative events must occur to permit a tumor cell to colonize a distant site successfully. To identify mouse strains that h
Publikováno v:
American journal of human genetics. 60(1)
Two kindreds residing in eastern Missouri and exhibiting X-linked recessive idiopathic hypoparathyroidism have been described. Genealogical records extending back five generations revealed no common ancestor. To investigate the possibility of related
Autor:
T R, Rebbeck, A H, Walker, C M, Phelan, A K, Godwin, K H, Buetow, J E, Garber, S A, Narod, B L, Weber
Publikováno v:
Progress in clinical and biological research. 396
Most breast cancer has a complex, multifactorial etiology. One consequence of this multifactorial phenomenon is that etiological heterogeneity may exist. This heterogeneity implies simply that two or more groups of breast cancer cases in the general
Publikováno v:
Molecular carcinogenesis. 17(3)
Genes involved in the metabolic activation or detoxification of environmental carcinogens may contribute to breast cancer susceptibility by influencing rates of somatic mutation. To examine this hypothesis, we studied the association between loss of
Autor:
D C, Schultz, L, Vanderveer, K H, Buetow, M P, Boente, R F, Ozols, T C, Hamilton, A K, Godwin
Publikováno v:
Cancer research. 55(10)
We have examined 41 forms of ovarian cancer for genetic alterations on chromosome 9 using a combination of five RFLP DNA probes and 15 simple tandem repeat polymorphisms. Genetic imbalance (i.e., loss of heterozygosity, microsatellite instability, am
Publikováno v:
Genetic epidemiology. 12(4)
Linkage analysis can be used to test the hypothesis that a marker locus of known location segregates independently from a presumed disease gene. One way to test this hypothesis is to measure the similarity of marker alleles among pairs of relatives a
Autor:
A, Sander, J C, Murray, T, Scherpbier-Heddema, K H, Buetow, J, Weissenbach, M, Zingg, K, Ludwig, R, Schmelzle
Publikováno v:
American journal of human genetics. 56(1)
Van der Woude syndrome (VWS) is an autosomal dominant craniofacial disorder characterized by lip pits, clefting of the primary or secondary palate, and hypodontia. The gene has been localized, by RFLP-based linkage studies, to region 1q32-41 between