Zobrazeno 1 - 10
of 73
pro vyhledávání: '"K H, Antonin"'
Autor:
K. H. Antonin, P. R. Bieck
Publikováno v:
Early Phase Drug Evaluation in Man ISBN: 9781349107070
Most drugs are administered orally, and the gastrointestinal tract is frequently exposed to high concentrations of substances given with the aim of acting at low concentrations elsewhere in the body. It is known that a number of drugs influence physi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0567f2820ace39194a1dfea24b91d590
https://doi.org/10.1201/9780367812454-44
https://doi.org/10.1201/9780367812454-44
Publikováno v:
Fortschritte der Neurologie · Psychiatrie. 66:S13-S16
Publikováno v:
European Journal of Clinical Pharmacology. 49:387-391
The pharmacokinetics of brofaromine, a selective inhibitor of monoamine oxidase A, was evaluated in 12 frail elderly patients (66-92 y) and 12 healthy volunteers (20-35 y).Quantitative liver function tests were performed to show whether brofaromine e
Autor:
Margherita Strolin Benedetti, Erik B. Nilsson, Peter C. Waldmeier, P. R. Bieck, Eckhart K. Schmidt, Gisbert Farger, K. H. Antonin, Philippe Dostert
Publikováno v:
Neurochemical Research. 18:1163-1167
CGP 28,014 is a specific inhibitor of catechol-O-methyltransferase (COMT) in vivo. In humans, the inhibition was assessed by measuring urinary excretion of isoquinolines and with the levodopa test. Following administration of CGP 28,014, urinary excr
Publikováno v:
Drug Investigation. 4:149-154
The interaction between the sympathomimetic agents phenylephrine and phenylpropanol-amine (as used in cold remedies or anorexiants) and the new selective and reversible MAO-A inhibitor brofaromine (Consonar®) 75mg administered twice daily for 10 day
Publikováno v:
European Journal of Clinical Pharmacology. 42:137-141
The pressor effect of intravenous tyramine (TYR) and noradrenaline (NA) has been evaluated, respectively, in 157 tests in 19 healthy unmedicated subjects, and in 202 tests in 24 similar subjects, all of whom took part in greater than or equal to 3 te
Autor:
K H, Antonin, B, Burkhard
Publikováno v:
Versicherungsmedizin. 55(1)
Tasks concerning environmental medicine are a significant aspect of the expert work done by the medical review board of the social health insurance fund. Thus far there are no commonly accepted theories and/or criteria with regard to the cause of env
Publikováno v:
European Journal of Clinical Pharmacology. 44:93-95
The optically active isomers of the racemic tetracyclic antidepressant oxaprotiline, R (-) oxaprotiline CGP 12,103 A (levoprotiline) and the S (+) oxaprotiline CGP 12,104 A, have been used as tools for a methodological Phase I study. Only the S (+) e
Publikováno v:
Fortschritte der Neurologie-Psychiatrie. 66