Zobrazeno 1 - 10
of 266
pro vyhledávání: '"K Gustavsson"'
Publikováno v:
New Journal of Physics, Vol 22, Iss 1, p 013033 (2020)
We analyse the spatial inhomogeneities (‘spatial clustering’) in the distribution of particles accelerated by a force that changes randomly in space and time. To quantify spatial clustering, the phase-space dynamics of the particles must be proje
Externí odkaz:
https://doaj.org/article/31c416d3fb9e458cb78bda29d19124be
Publikováno v:
New Journal of Physics, Vol 21, Iss 8, p 083008 (2019)
We study the angular dynamics of small non-spherical particles settling in a turbulent flow, such as ice crystals in clouds, aggregates of organic material in the oceans, or fibres settling in turbulent pipe flow. Most solid particles encountered in
Externí odkaz:
https://doaj.org/article/397714be917e4690b45fb0176dd578a9
Publikováno v:
New Journal of Physics, Vol 14, Iss 11, p 115017 (2012)
We have performed numerical simulations of inertial particles in random model flows in the white-noise limit (at zero Kubo number, Ku = 0) and at finite Kubo numbers. Our results for the moments of relative inertial-particle velocities are in good ag
Externí odkaz:
https://doaj.org/article/530e2de9579241b091e08399c5d846ee
Autor:
Lynne Krohn, Karl Heilbron, Cornelis Blauwendraat, Regina H. Reynolds, Eric Yu, Konstantin Senkevich, Uladzislau Rudakou, Mehrdad A. Estiar, Emil K. Gustavsson, Kajsa Brolin, Jennifer A. Ruskey, Kathryn Freeman, Farnaz Asayesh, Ruth Chia, Isabelle Arnulf, Michele T. M. Hu, Jacques Y. Montplaisir, Jean-François Gagnon, Alex Desautels, Yves Dauvilliers, Gian Luigi Gigli, Mariarosaria Valente, Francesco Janes, Andrea Bernardini, Birgit Högl, Ambra Stefani, Abubaker Ibrahim, Karel Šonka, David Kemlink, Wolfgang Oertel, Annette Janzen, Giuseppe Plazzi, Francesco Biscarini, Elena Antelmi, Michela Figorilli, Monica Puligheddu, Brit Mollenhauer, Claudia Trenkwalder, Friederike Sixel-Döring, Valérie Cochen De Cock, Christelle Charley Monaca, Anna Heidbreder, Luigi Ferini-Strambi, Femke Dijkstra, Mineke Viaene, Beatriz Abril, Bradley F. Boeve, andMe Research Team, Sonja W. Scholz, Mina Ryten, Sara Bandres-Ciga, Alastair Noyce, Paul Cannon, Lasse Pihlstrøm, Mike A. Nalls, Andrew B. Singleton, Guy A. Rouleau, Ronald B. Postuma, Ziv Gan-Or
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
REM-sleep behavior disorder often precedes Parkinson’s disease or dementia. Here, the authors perform a genome-wide association study for REM-sleep behavior disorder, and discover how it potentially affects gene expression in the brain.
Externí odkaz:
https://doaj.org/article/59eca1d6c47b4c98aed465f4c7a60228
Autor:
Zhongbo Chen, David Zhang, Regina H. Reynolds, Emil K. Gustavsson, Sonia García-Ruiz, Karishma D’Sa, Aine Fairbrother-Browne, Jana Vandrovcova, International Parkinson’s Disease Genomics Consortium (IPDGC), John Hardy, Henry Houlden, Sarah A. Gagliano Taliun, Juan Botía, Mina Ryten
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Knowledge of genomic features specific to humans may be important for understanding disease. Here the authors demonstrate a potential role for these human-lineage-specific sequences in brain development and neurological disease.
Externí odkaz:
https://doaj.org/article/adb7017084874dddbf672c99a5595752
Autor:
Sonia García-Ruiz, Emil K Gustavsson, David Zhang, Regina H Reynolds, Zhongbo Chen, Aine Fairbrother-Browne, Ana Luisa Gil-Martínez, Juan A Botia, Leonardo Collado-Torres, Mina Ryten
Publikováno v:
Nucleic Acids Research. 51:D167-D178
Dysregulation of RNA splicing contributes to both rare and complex diseases. RNA-sequencing data from human tissues has shown that this process can be inaccurate, resulting in the presence of novel introns detected at low frequency across samples and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad4747113a67057bfb534cedffd06408
https://doi.org/10.1093/nar/gkac1056
https://doi.org/10.1093/nar/gkac1056
Autor:
Yasuo Nakahara, Jun Mitsui, Hidetoshi Date, Kristine Joyce Porto, Yasuhiro Hayashi, Atsushi Yamashita, Yoshio Kusakabe, Takashi Matsukawa, Hiroyuki Ishiura, Tsutomu Yasuda, Atsushi Iwata, Jun Goto, Yaeko Ichikawa, Yoshio Momose, Yuji Takahashi, Tatsushi Toda, Rikifumi Ohta, Jun Yoshimura, Shinichi Morishita, Emil K Gustavsson, Darren Christy, Melissa Maczis, Matthew J. Farrer, Han-Joon Kim, Sung-Sup Park, Beomseok Jeon, Jin Zhang, Weihong Gu, Sonja W. Scholz, Andrew B. Singleton, Henry Houlden, Ichiro Yabe, Hidenao Sasaki, Masaaki Matsushima, Hiroshi Takashima, Akio Kikuchi, Masashi Aoki, Kenju Hara, Akiyoshi Kakita, Mitsunori Yamada, Hitoshi Takahashi, Osamu Onodera, Masatoyo Nishizawa, Hirohisa Watanabe, Mizuki Ito, Gen Sobue, Kinya Ishikawa, Hidehiro Mizusawa, Kazuaki Kanai, Satoshi Kuwabara, Kimihito Arai, Shigeru Koyano, Yoshiyuki Kuroiwa, Kazuko Hasegawa, Tatsuhiko Yuasa, Kenichi Yasui, Kenji Nakashima, Hijiri Ito, Yuishin Izumi, Ryuji Kaji, Takeo Kato, Susumu Kusunoki, Yasushi Osaki, Masahiro Horiuchi, Ken Yamamoto, Mihoko Shimada, Taku Miyagawa, Yosuke Kawai, Nao Nishida, Katsushi Tokunaga, Alexandra Dürr, Alexis Brice, Alessandro Filla, Thomas Klockgether, Ullrich Wüllner, Caroline M. Tanner, Walter A. Kukull, Virginia M.-Y. Lee, Eliezer Masliah, Phillip A. Low, Paola Sandroni, Laurie Ozelius, Tatiana Foroud, Shoji Tsuji
To elucidate the molecular basis of multiple system atrophy (MSA), a neurodegenerative disease, we conducted a genome-wide association study (GWAS) in a Japanese MSA case/control series followed by replication studies in Japanese, Korean, Chinese, Eu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0ca23eb995d2b34d1429411448aeb26
https://doi.org/10.1101/2023.05.02.23289328
https://doi.org/10.1101/2023.05.02.23289328
Autor:
S García-Ruiz, D Zhang, E K Gustavsson, G Rocamora-Perez, M Grant-Peters, A Fairbrother-Browne, R H Reynolds, J W Brenton, A L Gil-Martínez, Z Chen, D C Rio, J A Botia, S Guelfi, L Collado-Torres, M Ryten
Publikováno v:
bioRxiv
Alternative splicing impacts most multi-exonic human genes. Inaccuracies during this process may have an important role in ageing and disease. Here, we investigated mis-splicing using RNA-sequencing data from ~14K control samples and 42 human body si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::712fe5ec02d2d58ff6c1365f88fe13b4
https://europepmc.org/articles/PMC10081249/
https://europepmc.org/articles/PMC10081249/
Autor:
Malan Johansen, Sofus Joensen, Marjun Restorff, Tórmóður Stórá, Darren Christy, Emil K. Gustavsson, Jiang Bian, Yi Guo, Matthew J. Farrer, Maria Skaalum Petersen
Publikováno v:
European Journal of Neurology. 29:2192-2200
The Faroe Islands are a geographically isolated population in the North Atlantic with a similar prevalence of Alzheimer's disease (AD) and all-cause dementia as other European populations. However, the genetic risk underlying AD and other dementia su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee38aae3e01438ec197b3ec53aa1a90
https://doi.org/10.1111/ene.15351
https://doi.org/10.1111/ene.15351
Publikováno v:
Bioinformatics. 38:3844-3846
MotivationThe advent of long-read sequencing technologies has increased demand for the visualisation and interpretation of transcripts. However, tools that perform such visualizations remain inflexible and lack the ability to easily identify differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458c14803ff679185f7d5dd2aa50eca7
https://doi.org/10.1093/bioinformatics/btac409
https://doi.org/10.1093/bioinformatics/btac409