Zobrazeno 1 - 10
of 857
pro vyhledávání: '"K Groen"'
Autor:
Annika Wahlström, Ömrüm Aydin, Lisa M. Olsson, Wilhelm Sjöland, Marcus Henricsson, Annika Lundqvist, Hanns-Ulrich Marschall, Rutger Franken, Arnold van de Laar, Victor Gerdes, Abraham S. Meijnikman, Dag Hofsø, Albert K. Groen, Jøran Hjelmesæth, Max Nieuwdorp, Fredrik Bäckhed
Publikováno v:
EBioMedicine, Vol 106, Iss , Pp 105265- (2024)
Summary: Background: Bariatric surgery is an effective treatment option for obesity and provides long-term weight loss and positive effects on metabolism, but the underlying mechanisms are poorly understood. Alterations in bile acid metabolism have b
Externí odkaz:
https://doaj.org/article/64840ca30a314f63b2613355386bee20
Autor:
Guido J. Bakker, Abraham S. Meijnikman, Torsten P. Scheithauer, Mark Davids, Ömrüm Aydin, Thomas C. C. Boerlage, L. Maurits deBrauw, Arnold W. van deLaar, Victor E. Gerdes, Albert K. Groen, Daniël H. vanRaalte, Hilde Herrema, Max Nieuwdorp
Publikováno v:
Obesity Science & Practice, Vol 8, Iss 1, Pp 56-65 (2022)
Abstract Aims Visceral adipose tissue inflammation is a fundamental mechanism of insulin resistance in obesity and type 2 diabetes. Translocation of intestinal bacteria has been suggested as a driving factor for the inflammation. However, although ba
Externí odkaz:
https://doaj.org/article/8634882a32a6483e959e0f2d98ad71e1
Autor:
Maaike Blankestijn, Vincent W. Bloks, Dicky Struik, Nicolette Huijkman, Niels Kloosterhuis, Justina C. Wolters, Ronald J. A. Wanders, Frédéric M. Vaz, Markus Islinger, Folkert Kuipers, Bart van de Sluis, Albert K. Groen, Henkjan J. Verkade, Johan W. Jonker
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Peroxisomes play an important role in the metabolism of a variety of biomolecules, including lipids and bile acids. Peroxisomal Membrane Protein 4 (PXMP4) is a ubiquitously expressed peroxisomal membrane protein that is transcriptionally reg
Externí odkaz:
https://doaj.org/article/4641e716dcdd48d6b1399eb16d2429df
Autor:
Abraham S. Meijnikman, Dimitra Lappa, Hilde Herrema, Omrum Aydin, Kimberly A. Krautkramer, Valentina Tremaroli, Louise E. Olofsson, Annika Lundqvist, Sjoerd Bruin, Yair Acherman, Joanne Verheij, Siv Hjorth, Victor E.A. Gerdes, Thue W. Schwartz, Albert K. Groen, Fredrik Bäckhed, Jens Nielsen, Max Nieuwdorp
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104828- (2022)
Summary: Non-alcoholic fatty liver disease (NAFLD) is now the most frequent global chronic liver disease. Individuals with NAFLD exhibited an increased risk of all-cause mortality driven by extrahepatic cancers and liver and cardiovascular disease. O
Externí odkaz:
https://doaj.org/article/ed8d0c4c87de4b7a9a28489d9121d7d3
Autor:
Julia J. Witjes, Loek P. Smits, Ceyda T. Pekmez, Andrei Prodan, Abraham S. Meijnikman, Marian A. Troelstra, Kristien E.C. Bouter, Hilde Herrema, Evgeni Levin, Adriaan G. Holleboom, Maaike Winkelmeijer, Ulrich H. Beuers, Krijn vanLienden, Judith Aron‐Wisnewky, Ville Mannisto, Jacques J. Bergman, Jurgen H. Runge, Aart J. Nederveen, Lars O. Dragsted, Prokopis Konstanti, Erwin G. Zoetendal, Willem deVos, Joanne Verheij, Albert K. Groen, Max Nieuwdorp
Publikováno v:
Hepatology Communications, Vol 4, Iss 11, Pp 1578-1590 (2020)
The intestinal microbiota has been linked to the development and prevalence of steatohepatitis in humans. Interestingly, steatohepatitis is significantly lower in individuals taking a plant‐based, low‐animal‐protein diet, which is thought to be
Externí odkaz:
https://doaj.org/article/3a828877c8044547b262b85e4264f55c
Autor:
Annick V. Hartstra, Pieter F. deGroot, Diogo Mendes Bastos, Evgeni Levin, Mireille J. Serlie, Maarten R. Soeters, Ceyda T. Pekmez, Lars O. Dragsted, Mariette T. Ackermans, Albert K. Groen, Max Nieuwdorp
Publikováno v:
Obesity Science & Practice, Vol 6, Iss 3, Pp 340-349 (2020)
Summary Objective Insulin resistance develops prior to the onset of overt type 2 diabetes, making its early detection vital. Direct accurate evaluation is currently only possible with complex examinations like the stable isotope‐based hyperinsuline
Externí odkaz:
https://doaj.org/article/ca10f7dadf494d05b97a0ed7f1791360
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-9 (2020)
Abstract Background Epidemiological studies substantiated that subjects with elevated lipoprotein(a) [Lp(a)] have a markedly increased cardiovascular risk. Inhibition of proprotein convertase subtilisin/kexin type 9 (PCSK9) lowers both LDL cholestero
Externí odkaz:
https://doaj.org/article/304998e60c55467cab6966bfd00b82d0
Publikováno v:
BMC Biomedical Engineering, Vol 1, Iss 1, Pp 1-12 (2019)
Abstract Background Triple tracer meal experiments used to investigate organ glucose-insulin dynamics, such as endogenous glucose production (EGP) of the liver are labor intensive and expensive. A procedure was developed to obtain individual liver re
Externí odkaz:
https://doaj.org/article/7be627845afa43c6ace07c41a1a3b587
Autor:
K. Groen, M. R. Seefat, B. van der Holt, F. H. Schjesvold, C. A. Stege, M.-D. Levin, M. Hansson, R. B. Leys, J. Regelink, A. Waage, D. Szatkowski, P. Axelsson, T. H. Do, A. Svirskaite, E. van der Spek, E. Haukas, D. Knut-Bojanowska, P. F. Ypma, C. Blimark, U.-H. Mellqvist, N. W. van de Donk, P. Sonneveld, A. Klostergaard, A. J. Vangsted, N. Abdilgaard, S. Zweegman
Publikováno v:
HemaSphere, Vol 6, Pp 796-797 (2022)
Externí odkaz:
https://doaj.org/article/c6b62ee6d55f454d854f379f23c046b0
Autor:
K. Groen, M. Seefat, K. Nasserinejad, C. A. Stege, E. van der Spek, Y. M. Bilgin, A. Kentos, M. Sohne, R. J. van Kampen, I. Ludwig, N. Thielen, N. Durdu-Rayman, N. C. de Graauw, N. W. van de Donk, E. G. de Waal, M.-C. Vekemans, G. J. Timmers, M. van der Klift, S. Soechit, P. A. Geerts, M. H. Silbermann, M. Oosterveld, I. Nijhof, P. Sonneveld, S. K. Klein, M.-D. Levin, S. Zweegman
Publikováno v:
HemaSphere, Vol 6, Pp 797-798 (2022)
Externí odkaz:
https://doaj.org/article/de7b33949bb645c785d0c3c2f76a5ff0