Zobrazeno 1 - 5
of 5
pro vyhledávání: '"K G Waddick"'
Autor:
K G Waddick, Mridula Chandan-Langlie, Chang W. Song, Kazimiera J. Gajl-Peczalska, F. M. Uckun, W Jaszcz
Publikováno v:
Journal of Clinical Investigation. 91:1044-1051
The radiation sensitivity of primary clonogenic blasts from 44 children with newly diagnosed B-cell precursor acute lymphoblastic leukemia (ALL) was analyzed using leukemic progenitor cell (LPC) colony assays. The derived values for SF2 (surviving fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::624e320817883cac1077ee8390a7c564
https://doi.org/10.1172/jci116261
https://doi.org/10.1172/jci116261
Autor:
K G, Waddick, F M, Uckun
Publikováno v:
Biochemical pharmacology. 57(1)
Nuclear factor-kappaB (NF-kappaB) activity affects cell survival and determines the sensitivity of cancer cells to cytotoxic agents as well as to ionizing radiation. Preventing the protective function of NF-kappaB may result in chemo- and radio-sensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34269df82317d084ad26a71e1935f5a0
https://pubmed.ncbi.nlm.nih.gov/9920280
https://pubmed.ncbi.nlm.nih.gov/9920280
Autor:
F M, Uckun, L, Tuel-Ahlgren, K G, Waddick, X, Jun, J, Jin, D E, Myers, R B, Rowley, A L, Burkhardt, J B, Bolen
Publikováno v:
The Journal of biological chemistry. 271(11)
Exposure of human B-cell precursors (BCP) to ionizing radiation results in cell cycle arrest at the G2-M checkpoint as a result of inhibitory tyrosine phosphorylation of p34cdc2 . Here, we show that ionizing radiation promotes physical interactions b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::498f4be798152b084340496612c59343
https://pubmed.ncbi.nlm.nih.gov/8626437
https://pubmed.ncbi.nlm.nih.gov/8626437
Publikováno v:
Radiation research. 136(3)
As presently reported, both ionizing radiation and engagement of the CD19 receptor are capable of inducing apoptosis in B-lineage acute lymphoblastic leukemia (ALL) cells. In both instances, activation of tyrosine kinases appears to be a proximal and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9338546cf70234032ff9af8974b8f7d3
https://pubmed.ncbi.nlm.nih.gov/7506428
https://pubmed.ncbi.nlm.nih.gov/7506428
Autor:
K G, Waddick, F M, Uckun
Publikováno v:
Experimental hematology. 21(6)
We examined bone marrow and peripheral blood specimens from pediatric acute lymphoblastic leukemia (ALL) patients after autologous bone marrow transplantation (BMT) as well as fetal lymphohematopoietic tissues for the presence of CD5+ B lymphocytes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9449bade6ec91726332a1f012ab9df90
https://pubmed.ncbi.nlm.nih.gov/7684704
https://pubmed.ncbi.nlm.nih.gov/7684704