Zobrazeno 1 - 10
of 22
pro vyhledávání: '"K G, Tolman"'
Publikováno v:
Clinical pharmacy. 11(6)
The effect of a single dose or oral lactase on symptoms, breath hydrogen concentration, and glucose absorption in lactose-intolerant subjects challenged with lactose was studied. Volunteers underwent a lactose challenge test; those whose breath hydro
Autor:
Daniel O. Clegg, P A Leonard, J R Ward, G J Roth, Robert F. Willkens, Christopher G. Jackson, K G Tolman, C R Marks, Grant W. Cannon, M L Greene
Publikováno v:
Annals of the rheumatic diseases. 49(8)
The liver histology of 52 patients treated with intermittent low dose pulse methotrexate for rheumatoid arthritis was evaluated using a modification of the Roenigk grading system. Patients studied had had an average of 3.2 years of treatment or had r
Autor:
J L, Ferrero, B A, Bopp, K C, Marsh, S C, Quigley, M J, Johnson, D J, Anderson, J E, Lamm, K G, Tolman, S W, Sanders, J H, Cavanaugh
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 18(4)
The metabolic fate and pharmacokinetics of clarithromycin following a single 250- or 1200-mg oral dose of 14C-clarithromycin were studied in six healthy adult males. Peak plasma levels of clarithromycin averaged 0.6 microgram/ml after the low dose an
Autor:
K G, Tolman
Publikováno v:
The Journal of rheumatology. Supplement. 22
The central role of the liver in drug metabolism makes it vulnerable to toxic injury. Drug induced liver injury may mimic any of the naturally occurring liver diseases. The rheumatic diseases themselves may have liver disease associated with them, ma
Autor:
R R, Luther, G L, Ringham, F J, Steinberg, K J, Patterson, D C, Jordan, D E, Rollins, K G, Tolman
Publikováno v:
The Journal of Clinical Pharmacology. 27:794-801
The pharmacologic effects of A-49816, a high-ceiling, loop diuretic, were evaluated in a single-blind, placebo-controlled, randomized trial. Eighteen (18) normal volunteers aged 19 to 40 years were divided into three groups. The subjects in each grou
Publikováno v:
Scandinavian Journal of Gastroenterology. 24:81-91
The antigastrolesive activity of rioprostil, an orally effective synthetic 16-methyl analogue of prostaglandin-E1, with potent antisecretory and antigastrolesive properties in animals, is evaluated in a series of studies involving 166 healthy male vo
Publikováno v:
Clinical therapeutics. 10(5)
Terazosin, a new long-acting selective alpha 1-receptor antagonist, was studied in a crossover trial to assess the effect of age on oral and intravenous pharmacokinetics. Thirty healthy male and female volunteers between the ages of 23 and 75 years r
Publikováno v:
Investigative radiology. 15
Radiologists are familiar with certain toxic manifestations of biliary and urinary contrast media (ie, acute tubular necrosis in dehydrated patients with diabetes or multiple myeloma), and with the specific effects of contrast media on other diagnost
Publikováno v:
Gastroenterology. 74(2 Pt 1)
The influence of graded doses of sodium salicylate on rat liver cells cultured in monolayers was assessed by measuring lactic dehydrogenase activity in a culture media after incubation. Morphological alterations were studied by electron microscopy. T
Publikováno v:
Scandinavian journal of gastroenterology. Supplement. 164
The antigastrolesive activity of rioprostil, an orally effective synthetic 16-methyl analogue of prostaglandin-E1, with potent antisecretory and antigastrolesive properties in animals, is evaluated in a series of studies involving 166 healthy male vo