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Publikováno v:
Clinical chemistry. 47(11)
Publikováno v:
Clinical chemistry. 43(3)
P-glycoprotein (Pgp) is a 170-kDa membrane transporter that mediates drug efflux and is an effector of multidrug resistance. SDZ PSC 833 (PSC), a nonimmunosuppressive cyclosporine that potently modulates Pgp, is currently under clinical evaluation in