Zobrazeno 1 - 10
of 1 474
pro vyhledávání: '"K Fletcher"'
Autor:
J Mant, J Doust, A Roalfe, P Barton, MR Cowie, P Glasziou, D Mant, RJ McManus, R Holder, J Deeks, K Fletcher, M Qume, S Sohanpal, S Sanders, FDR Hobbs
Publikováno v:
Health Technology Assessment, Vol 13, Iss 32 (2009)
Objectives: To assess the accuracy in diagnosing heart failure of clinical features and potential primary care investigations, and to perform a decision analysis to test the impact of plausible diagnostic strategies on costs and diagnostic yield in t
Externí odkaz:
https://doaj.org/article/56c60e980a2b461a982de45fbfc22df7
Autor:
Annelise Pesch, Karlena D. Ochoa, Katelyn K. Fletcher, Vanessa N. Bermudez, Rachael D. Todaro, Julie Salazar, Hailey M. Gibbs, June Ahn, Andres S. Bustamante, Kathy Hirsh-Pasek
Publikováno v:
Frontiers in Psychology, Vol 13 (2022)
What if the environment could be transformed in culturally-responsive and inclusive ways to foster high-quality interactions and spark conversations that drive learning? In this article, we describe a new initiative accomplishing this, called Playful
Externí odkaz:
https://doaj.org/article/a73dc00d9ebe4f6e991d3fc6688da40c
Autor:
Marcia A. Munoz, Oliver P. Skinner, Etienne Masle-Farquhar, Julie Jurczyluk, Ya Xiao, Emma K. Fletcher, Esther Kristianto, Mark P. Hodson, Seán I. O’Donoghue, Sandeep Kaur, Robert Brink, David G. Zahra, Elissa K. Deenick, Kristen A. Perry, Avril A.B. Robertson, Sam Mehr, Pravin Hissaria, Catharina M. Mulders-Manders, Anna Simon, Michael J. Rogers
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 19 (2022)
Mevalonate kinase deficiency (MKD) is characterized by recurrent fevers and flares of systemic inflammation, caused by biallelic loss-of-function mutations in MVK. The underlying disease mechanisms and triggers of inflammatory flares are poorly under
Externí odkaz:
https://doaj.org/article/21b5b88799f3482d9c5c720c2d6c2ea8
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1493-1512 (2021)
Macrophages are typically identified as classically activated (M1) macrophages and alternatively activated (M2) macrophages, which respectively exhibit pro- and anti-inflammatory phenotypes, and the balance between these two subtypes plays a critical
Externí odkaz:
https://doaj.org/article/bb5127c5325546ccbec51fcfba0227ce
Autor:
Li Yang, Te Liang, Lane M. Pierson, Hongye Wang, Jesse K. Fletcher, Shu Wang, Duran Bao, Lili Zhang, Zhen Huang, Wenshu Zheng, Xiaomei Zhang, Heewon Park, Yuwen Li, James E. Robinson, Amy K. Feehan, Christopher J. Lyon, Jing Cao, Lisa A. Morici, Chenzhong Li, Chad J. Roy, Xiaobo Yu, Tony Hu
Publikováno v:
Research, Vol 2022 (2022)
Identification of epitopes targeted following virus infection or vaccination can guide vaccine design and development of therapeutic interventions targeting functional sites, but can be laborious. Herein, we employed peptide microarrays to map linear
Externí odkaz:
https://doaj.org/article/3c5565859db147acb09b4f31677d9342
Autor:
Nicholas K. Fletcher, Pelayo Acevedo, Jeremy S. Herman, Joana Paupério, Paulo C. Alves, Jeremy B. Searle
Publikováno v:
Ecology and Evolution, Vol 9, Iss 24, Pp 14101-14113 (2019)
Abstract Understanding the factors that contribute to the generation of reproductively isolated forms is a fundamental goal of evolutionary biology. Cryptic species are an especially interesting challenge to study in this context since they lack obvi
Externí odkaz:
https://doaj.org/article/b475c793783b41868316180b878818ba
Autor:
Marcia A Munoz, Emma K Fletcher, Oliver P Skinner, Julie Jurczyluk, Esther Kristianto, Mark P Hodson, Shuting Sun, Frank H Ebetino, David R Croucher, Philip M Hansbro, Jacqueline R Center, Michael J Rogers
Publikováno v:
eLife, Vol 10 (2021)
Bisphosphonates drugs target the skeleton and are used globally for the treatment of common bone disorders. Nitrogen-containing bisphosphonates act by inhibiting the mevalonate pathway in bone-resorbing osteoclasts but, surprisingly, also appear to r
Externí odkaz:
https://doaj.org/article/efd2366c282f45e0a4b6b5d87db2968d
Publikováno v:
International Journal of Web Services Research. 20:1-17
With the rapid development of service computing and software technologies, it is necessary to correctly and efficiently classify web services to promote their discovery and application. The existing service classification methods based on heterogeneo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2e18aab893d6f4a1646eb5fc9e3528e
https://doi.org/10.4018/ijwsr.319960
https://doi.org/10.4018/ijwsr.319960
Autor:
Alice Redfern, Ntuli A Kapologwe, Taylor Salisbury, Erin K Fletcher, Jean Arkedis, Felix Bundala, Alison Connor, Julius Massaga, Naibu Mkongwa, Balowa Musa, Cammie Lee
Publikováno v:
BMJ Open, Vol 11, Iss 5 (2021)
Objective This study compares two methods for clinical diagnosis of childhood pneumonia that aim to estimate rates of underdiagnosis and overdiagnosis of childhood pneumonia by examining the sensitivity of Integrated Management of Childhood Diseases
Externí odkaz:
https://doaj.org/article/7276fa75d2614075aa28eba00c71e964
Autor:
Isabel K Fletcher, MSc, Juan Hernández-Villena, BSc, Jorge E Moreno, PhD, Chris Drakeley, ProfPhD, Kate Jones, ProfPhD, Maria Eugenia Grillet, ProfPhD, Rachel Lowe, PhD
Publikováno v:
The Lancet Planetary Health, Vol 5, Iss , Pp S13- (2021)
Background: Malaria transmission is highly dependent on environmental conditions. The association between climatic variables and malaria transmission is well established, but the interaction between variations in climate and land use change, such as
Externí odkaz:
https://doaj.org/article/6db37cf58980456a938260b6215e8f66