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Effects of carbamazepine on 5-hydroxytryptamine function in rodents

Autor: D. G. Grahame-Smith, S. M. P. Anderson, K. F. Hallis, Martin Elphick

Publikováno v: Psychopharmacology. 100(1)

The effects of carbamazepine (CBZ) on brain 5-hydroxytryptamine (5-HT) function were investigated in rodents pretreated with CBZ acutely or for 14 days. In behavioural experiments, mice pretreated with 14 days CBZ showed increased 5-HT2-mediated head

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::702d340d5961bfc7a5459f3a33c095a1
https://pubmed.ncbi.nlm.nih.gov/2136952

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In vivo cation transport during short-term and long-term digoxin therapy

Autor: Jeffrey K Aronson, K F Hallis, S E Pugh, D. G. Grahame-Smith, N A Boon

Publikováno v: British Journal of Clinical Pharmacology. 22:27-30

We have studied the effects of digoxin on cation transport in vivo by measuring the changes in plasma and red cell rubidium concentrations following an oral load of rubidium chloride. In eight patients who had been taking digoxin for 7 to 10 days (me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb9637ead1039ea193236482733edff
https://doi.org/10.1111/j.1365-2125.1986.tb02875.x

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A Method for the Study of Cation Transport in vivo: Effects of Digoxin Administration and of Chronic Renal Failure on the Disposition of An Oral Load of Rubidium Chloride

Autor: Nicholas J. White, Nicholas A. Boon, A. E. G. Raine, K F Hallis, Jeffrey K Aronson, David G. Grahame-Smith

Publikováno v: Clinical Science. 66:569-574

1. In order to study cation transport in vivo we have measured the changes in plasma and intra-erythrocytic rubidium concentrations following an oral load of rubidium chloride. The changes in plasma rubidium concentration are related to the distribut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2016e8fa1db97b560059c5229cf6e66e
https://doi.org/10.1042/cs0660569

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A sensitive high-temperature electrothermal atomic absorption analysis for Rb+ in erythrocytes and plasma of normal and hypertensive persons

Autor: K F, Hallis, N A, Boon, C M, Perkins, J K, Aronson, D G, Grahame-Smith

Publikováno v: Clinical chemistry. 31(2)

This method for determination of Rb+ in human plasma and erythrocytes by graphite-furnace atomic absorption spectrophotometry has a sensitivity of 29 nmol/L for plasma, 12 nmol/L for erythrocytes. The detection limit is 24 nmol/L for plasma, 4.8 nmol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c29407b4654614f827ca3ed54e9d4775
https://pubmed.ncbi.nlm.nih.gov/3967362

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Lack of effect of phenytoin on functions related to Na+,K+-ATPase activity of the intact erythrocytes of epileptic patients

Autor: K F Hallis, DP Geaney, Jeffrey K Aronson, JC Carver, D. G. Grahame-Smith

Publikováno v: British journal of clinical pharmacology. 12(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196488afec8e4f366ccec5be110b875f
http://ora.ox.ac.uk/objects/uuid:424770c1-d8ee-47e0-bd20-981f52779abd

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An in vivo study of cation transport in essential hypertension

Autor: N A, Boon, J K, Aronson, K F, Hallis, A E, Raine, D D, Grahame-Smith

Publikováno v: Journal of hypertension. Supplement : official journal of the International Society of Hypertension. 2(3)

In order to study cation transport in vivo the changes in plasma and red cell rubidium concentrations were measured following an oral load of rubidium chloride. Eight patients receiving short-term digoxin therapy, 10 patients with chronic renal failu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eedb504f5c7523fda97ded6ce4fe54e2
https://pubmed.ncbi.nlm.nih.gov/6100748

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