Zobrazeno 1 - 10 of 107 pro vyhledávání: '"K F Byth"'
1
Aberrant TCR-mediated signaling in CD45-null thymocytes involves dysfunctional regulation of Lck, Fyn, TCR-zeta, and ZAP-70
Autor: J D Stone, L A Conroy, K F Byth, R A Hederer, S Howlett, Y Takemoto, N Holmes, D R Alexander
Publikováno v: The Journal of Immunology. 158:5773-5782
CD45 is a transmembrane phosphotyrosine phosphatase expressed on all nucleated hemopoietic cells. Targeting of CD45 exon 9 has generated a mouse line completely lacking CD45 expression (CD45-null) in which there are severe abnormalities in T cell dev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1c03a8bd6648317d5915ab66daa561d5
https://doi.org/10.4049/jimmunol.158.12.5773
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2
Defective depletion of CD45-null thymocytes by the Staphylococcus aureus Enterotoxin B superantigen
Autor: Denis R. Alexander, K. F. Byth, Sarah Howlett, Nick Holmes, Louise A. Conroy
Publikováno v: Immunology Letters. 54:119-122
The development of a normal T-cell repertoire is critically dependent on the negative and positive selection events which occur at the CD4+CD8+ (double positive, DP) stage of thymic development. Depending on the avidity of the T-cell antigen receptor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dfcc8cb78e6a9061b1513338d1601b1
https://doi.org/10.1016/s0165-2478(96)02660-0
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5
CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation
Autor: K. F. Byth, L. A. Conroy, Nick Holmes, Denis R. Alexander, A. J. H. Smith, J. May, Sarah Howlett
Publikováno v: The Journal of Experimental Medicine
The CD45 transmembrane glycoprotein has been shown to be a protein phosphotyrosine phosphatase and to be important in signal transduction in T and B lymphocytes. We have employed gene targeting to create a strain of transgenic mice that completely la
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef84d85bf8617a036a9f4846e5ceea1d
https://pubmed.ncbi.nlm.nih.gov/8666928
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7
Akademický článek
Selenium Dioxide as a Source to make Se‐Containing Imidazoheterocycle or Aniline Derivatives.
Autor: Zhong, Zijian1 (AUTHOR), Ma, Jinfeng1 (AUTHOR), Xu, Pan1 (AUTHOR), Zhou, Aihua1 (AUTHOR) ahz@ujs.edu.cn
Publikováno v: ChemistrySelect. 12/13/2022, Vol. 7 Issue 46, p1-5. 5p.
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8
Akademický článek
Imidazo[1,2‐a]pyridine as a promising scaffold for the development of antibacterial agents.
Autor: Mishra, Nilima Priyadarsini1 (AUTHOR), Mohapatra, Seetaram1 (AUTHOR) seetaram.mohapatra@gmail.com, Das, Tapaswini1 (AUTHOR), Nayak, Sabita1 (AUTHOR)
Publikováno v: Journal of Heterocyclic Chemistry. Dec2022, Vol. 59 Issue 12, p2051-2075. 25p.
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9
Akademický článek
Antiproliferative Activity of (−)‐Isopulegol‐based 1,3‐Oxazine, 1,3‐Thiazine and 2,4‐Diaminopyrimidine Derivatives.
Autor: Bamou, Fatima Z.1 (AUTHOR), Le, Tam M.1 (AUTHOR), Tayeb, Bizhar A.2 (AUTHOR), Tahaei, Seyyed A. S.2 (AUTHOR), Minorics, Renáta2 (AUTHOR), Zupkó, István2 (AUTHOR), Szakonyi, Zsolt1 (AUTHOR) szakonyi.zsolt@szte.hu
Publikováno v: ChemistryOpen. Oct2022, Vol. 11 Issue 10, p1-11. 11p.
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10
Akademický článek
Lewis Acid Zn(OTf)2 Catalyzed Synthesis ofImidazo[1,2‐a]pyridines by [3+2] Annulation of 2‐Amino Pyridines and Propargylic Alcohols.
Autor: Medishetti, Nagaraju1,2 (AUTHOR), Ittamalla, Chaitanya1 (AUTHOR), Nanubolu, Jagadeesh Babu2,3 (AUTHOR), Atmakur, Krishnaiah1,2 (AUTHOR) krishnu@iict.res.in
Publikováno v: ChemistrySelect. 3/29/2022, Vol. 7 Issue 12, p1-4. 4p.
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