Zobrazeno 1 - 10
of 42
pro vyhledávání: '"K F, Swingle"'
Autor:
M. J. Reiter, A. M. Hupperts, M. A. Rustad, V. L. Stelzer, R. L. Bell, D. M. Hammerbeck, R. A. Scherrer, K. Heghinian, K. F. Swingle
Publikováno v:
Annals of the New York Academy of Sciences. 524:398-401
Publikováno v:
Journal of Medicinal Chemistry. 18:386-391
A series of isosteres of 3-benzoyltrifluoromethanesulfonanilide involving alternatives to the carbonyl linking group was synthesized and screened for antiinflammatory activity in the carrageenan rat paw edema test. The systems examined were of the ty
Autor:
M. J. Reiter, K. F. Swingle
Publikováno v:
Agents and actions. 18(3-4)
Three classes of drugs were found, after their i.p. administration, to inhibit Paf-acether-induced edema of the rat's paw. These were beta-adrenergic agonists (isoproterenol, salbutamol), alpha-adrenergic antagonists (prazosin, ergotamine, yohimbine,
Publikováno v:
Radiation research. 59(3)
Autor:
M. Van Winkle, K. F. Swingle, C. F. Hainline, T. K. Rice, Edward H. Erickson, Charles J. Matson, L. S. Lenon
Publikováno v:
Chemischer Informationsdienst. 10
Publikováno v:
Journal of medicinal chemistry. 21(9)
Substitution of 1,4-dihydro-4-oxoquinoline-2-carboxylic acid by acetyl, benzoyl, and phenylsulfonyl substituents was found to enhance activity in the rat passive cutaneous anaphylaxis assay. A further increase in activity, to equipotency with DSCG, w
Publikováno v:
Chemischer Informationsdienst. 10
Substitution of 1,4-dihydro-4-oxoquinoline-2-carboxylic acid by acetyl, benzoyl, and phenylsulfonyl substituents was found to enhance activity in the rat passive cutaneous anaphylaxis assay. A further increase in activity, to equipotency with DSCG, w
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 254(1)
The inflammatory response to topical application of cantharidin or croton oil to the mouse ear was studied. Croton oil dermatitis developed more rapidly and reached its apparent peak earlier than cantharidin dermatitis. Either dermatitis detected top
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 214(2)
The antiinflammatory activity of R-803 (alpha-methyl-3-phenyl-7-benzofuranacetic acid), a new nonsteroidal drug, has been demonstrated. The oral administration of R-803 inhibits carrageenan-induced edema of the rat's paw, ultraviolet-induced erythema
Autor:
K F, Swingle, D M, Hammerbeck, J R, Schmid, V L, Stelzer, M J, Reiter, A M, Peterson, J J, Wade
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 286(2)
The bronchodilator activity of R-386 (2,5-diethyl-7-(4-thiomorpholino)-1,2,4-triazolo[1,5-c]pyrimidine) was demonstrated in isolated guinea-pig tracheal preparations and in vivo in dogs, guinea-pigs and rats. Guinea-pig tracheal preparations contract