Zobrazeno 1 - 7
of 7
pro vyhledávání: '"K F, Byth"'
Publikováno v:
The Journal of Immunology. 158:5773-5782
CD45 is a transmembrane phosphotyrosine phosphatase expressed on all nucleated hemopoietic cells. Targeting of CD45 exon 9 has generated a mouse line completely lacking CD45 expression (CD45-null) in which there are severe abnormalities in T cell dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c03a8bd6648317d5915ab66daa561d5
https://doi.org/10.4049/jimmunol.158.12.5773
https://doi.org/10.4049/jimmunol.158.12.5773
Publikováno v:
Immunology Letters. 54:119-122
The development of a normal T-cell repertoire is critically dependent on the negative and positive selection events which occur at the CD4+CD8+ (double positive, DP) stage of thymic development. Depending on the avidity of the T-cell antigen receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dfcc8cb78e6a9061b1513338d1601b1
https://doi.org/10.1016/s0165-2478(96)02660-0
https://doi.org/10.1016/s0165-2478(96)02660-0
Autor:
J D, Stone, L A, Conroy, K F, Byth, R A, Hederer, S, Howlett, Y, Takemoto, N, Holmes, D R, Alexander
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 158(12)
CD45 is a transmembrane phosphotyrosine phosphatase expressed on all nucleated hemopoietic cells. Targeting of CD45 exon 9 has generated a mouse line completely lacking CD45 expression (CD45-null) in which there are severe abnormalities in T cell dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b5bdee15ffc6a10b6f762b02efa432f1
https://pubmed.ncbi.nlm.nih.gov/9190928
https://pubmed.ncbi.nlm.nih.gov/9190928
Publikováno v:
Biochemical Society transactions. 25(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15245806093317aa27b0946a312aa34f
https://pubmed.ncbi.nlm.nih.gov/9191346
https://pubmed.ncbi.nlm.nih.gov/9191346
Autor:
L. A. Conroy, J. D. Stone, Nick Holmes, J. A. Frearson, K. F. Byth, Sarah Howlett, Denis R. Alexander
Publikováno v:
Biochemical Society transactions. 25(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91558582d3c276945f6c968efdcb6024
https://pubmed.ncbi.nlm.nih.gov/9191133
https://pubmed.ncbi.nlm.nih.gov/9191133
Autor:
K. F. Byth, L. A. Conroy, Nick Holmes, Denis R. Alexander, A. J. H. Smith, J. May, Sarah Howlett
Publikováno v:
The Journal of Experimental Medicine
The CD45 transmembrane glycoprotein has been shown to be a protein phosphotyrosine phosphatase and to be important in signal transduction in T and B lymphocytes. We have employed gene targeting to create a strain of transgenic mice that completely la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef84d85bf8617a036a9f4846e5ceea1d
https://pubmed.ncbi.nlm.nih.gov/8666928
https://pubmed.ncbi.nlm.nih.gov/8666928
Publikováno v:
Biochemical Society Transactions. 24:609S-609S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cf2207476b56c0a6a35ba9567b27c9c
https://doi.org/10.1042/bst024609s
https://doi.org/10.1042/bst024609s